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Erythroblast membrane-associated protein

ERMAP, hERMAP
The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CD166, Ter, POLYMERASE, CD36, CD45
Papers on ERMAP
Differential expression of natural antisense transcripts during liver development in embryonic mice.
Chiba, Hirosaki, Japan. In Biomed Rep, 2014
Among these NATs, strand-specific reverse transcription-quantitative polymerase chain reaction analyses validated that the NAT expression of Fga, Fgb, Fgg, F2, Apoa1, Fabp1, C3 and Proc, which have metabolic and synthesizing functions in the adult liver, increased, whereas the NAT expression of Ermap and Tfrc, which function in the hematopoiesis, decreased during the developmental stages.
SC*994C>T causes the Sc(null) phenotype in Pacific Islanders and successful transfusion of Sc3+ blood to a patient with anti-Sc3.
Lomas-Francis et al., Hūn, Libya. In Immunohematology, 2012
Antigens in the SC blood group system are expressed by the human erythrocyte membrane-associated protein (ERMAP).Two molecular bases have been reported for the Sc,un phenotype:SC*307del2 and SC*994C>T.
Easy identification of antibodies to high-prevalence Scianna antigens and detection of admixed alloantibodies using soluble recombinant Scianna protein.
Flegel et al., Springe, Germany. In Transfusion, 2009
BACKGROUND: Identification of antibodies against high-prevalence Scianna (Sc; ERMAP) antigens, like Sc1 and Sc5, is difficult and may incur delays in blood procurement and costs.
[Effects of human ERMAP-siRNA on erythroid differentiation of K562 cells induced by Ara-C].
Gao et al., Guangzhou, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2009
It is concluded that the ERMAP-shRNA inhibits the Ara-C-induced erythroid differentiation of K562 cells, which further suggests that there is relationship between hERMAP and erythroid differentiation and development.
[Expression of human ermap gene in umbilical cord blood mononuclear cells during differentiation and development towards erythroid lineage].
GeneRIF
Liang et al., Guangzhou, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2008
The human ermap gene plays an important role in differentiation and development of erythroid cells.
[Expression of human ERMAP gene in fetal tissues].
Ye et al., Guangzhou, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2006
Human ERMAP (hERMAP) is a novel gene coding for erythroid membrane-associated protein, which may play a role in erythropoiesis.
SCER and SCAN: two novel high-prevalence antigens in the Scianna blood group system.
Wagner et al., Ulm, Germany. In Transfusion, 2005
All 11 SC (ERMAP) exons and their flanking regions were sequenced.
[Expression of human ERMAP gene in different cell lines].
Wu et al., Guangzhou, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2005
To investigate the pattern of human ERMAP gene expression in different cell lines, 15 cell lines derived from hematopoietic tumor, somatic tumor and normal tissue were chosen and were cultured; cells were harvested after culture for 12, 24, 36, 48, 60 and 72 hours; the expression of the human ERMAP was detected by using fluorescent quantitative PCR.
[Study on the expression of human ERMAP gene in erythropoietic and macrophage differentiation of K562 cells].
Wu et al., Guangzhou, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2005
In order to investigate the potential of human ERMAP gene in erythroid cell differentiation, K562 cells were induced to erythroid lineage by Ara-C and to macrophage lineage by TPA, human ERMAP mRNA was detected by fluorescent quantitative PCR.
STAR: a novel high-prevalence antigen in the Scianna blood group system.
Reid et al., New York City, United States. In Transfusion, 2005
DNA was extracted, and amplified products from all 11 SC (ERMAP) exons and their flanking regions of the proband were sequenced.
Scianna antigens including Rd are expressed by ERMAP.
GeneRIF
Flegel et al., Ulm, Germany. In Blood, 2003
DNA sequencing demonstrates Scianna antigens including Rd are expressed by ERMAP.
Human ERMAP: an erythroid adhesion/receptor transmembrane protein.
GeneRIF
Chui et al., Hamilton, Canada. In Blood Cells Mol Dis, 2001
A human cDNA and gene encoding for human ERMAP is cloned and characterized. The protein is sequenced and its expression analyzed.
Cloning and characterization of human erythroid membrane-associated protein, human ERMAP.
GeneRIF
Schueler et al., Berkeley, United States. In Genomics, 2001
ERMAP, a unique member of the B30.2 domain protein family, is expressed in erythroid cells in fetal liver, adult bone marrow, reticulocytes and in circulating erythroblasts in 8-12-week fetal cord blood.
Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.
Chui et al., Hamilton, Canada. In Gene, 2000
Ermap (erythroid membrane-associated protein), a gene coding for a novel transmembrane protein produced exclusively in erythroid cells, is described.
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