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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ets variant 5

ERM, ETV5
involved in regulating functional associations between the cell surface and the cytoskeleton [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: Ezrin, Actin, CAN, V1a, Rhodopsin
Papers using ERM antibodies
Increased efficacy for in-house validation of real-time PCR GMO detection methods
Supplier
Kok Esther J. et al., In Analytical and Bioanalytical Chemistry, 2009
... DAS59122, 9.87%), ERM-BF423d (SYN-IR6Ø4-5 or MIR604, 9.85%), ERM-BF422d (DAS-21Ø23-5 × DAS-24236-5 or 281-24-236 × 3006-210-23, 10%) (European Reference Materials, ERM, Geel, Belgium) and AOCS 0906-E (MON-89Ø34-3 or MON89034, >99.42%),
Misexpression of chick Vg1 in the marginal zone induces primitive streak formation
Supplier
Dodd Jane et al., In Neural Development, 1996
... ]), mouse α-ERM (13 H9; [36]), rabbit α-HA, mouse α-HA (Abcam, Cambridge, MA, USA), mouse ...
Inhibition and Redistribution of NHE3, the Apical Na+/H+ Exchanger, by Clostridium difficile Toxin B
Supplier
Grinstein Sergio et al., In The Journal of General Physiology, 1994
... The antiphospho-ezrin/radixin/moesin (antiphospho-ezrin [Thr567]/radixin [Thr 564]/moesin [Thr 558], referred to hereafter as phospho-ERM) antibody was from Cell Signaling (1:1,000 dilution for immunoblotting ...
Anatomy of the human retinal pigment epithelium
Supplier
Rodriguez-Boulan Enrique et al., In The Journal of Cell Biology, 1978
... polyclonal antibody (pAb) C-19 directed to the peptide 566–584 of human ezrin (conserved in all ERM proteins) was purchased from Santa Cruz Biotechnology, Inc ...
Papers on ERM
In human T cells mifepristone antagonizes glucocorticoid non-genomic rapid responses in terms of Na(+)/H(+)-exchange 1 activity, but not ezrin/radixin/moesin phosphorylation.
New
Lin et al., Taipei, Taiwan. In Steroids, Feb 2016
NHE1 is tethered to the cortical actin cytoskeleton through ezrin/radixin/moesin (ERM) proteins within lipid rafts; these regulate cell shape, migration and resistance to apoptosis.
Yersinia ruckeri lipopolysaccharide is necessary and sufficient for eliciting a protective immune response in rainbow trout (Oncorhynchus mykiss, Walbaum).
New
LaPatra et al., United States. In Fish Shellfish Immunol, Feb 2016
UNASSIGNED: Enteric redmouth disease (ERM), caused by Yersinia ruckeri, has been controlled successfully using immersion-applied bacterin vaccines for several decades.
Regulation of c-Maf and αA-crystallin in Ocular Lens by FGF Signaling.
New
Cvekl et al., United States. In J Biol Chem, Jan 2016
Chromatin immunoprecipitation (ChIP) assays established binding of c-Jun (an AP-1 factor) and Etv5/ERM (an Ets factor) to these regions in lens chromatin.
β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.
New
Impact
Dixit et al., San Francisco, United States. In Cell, Jan 2016
Here, we show that post-translational regulation of the transcription factors ETV1, ETV4, and ETV5 by the ubiquitin ligase COP1 (also called RFWD2) in β cells is critical for insulin secretion.
Resistin, a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation.
New
Kim et al., Seoul, South Korea. In Sci Rep, Dec 2015
Resistin also increased phosphorylation of ezrin, radixin, and moesin (ERM).
Ezrin: a regulator of actin microfilaments in cell junctions of the rat testis.
Review
New
Cheng et al., New York City, United States. In Asian J Androl, Jul 2015
Ezrin, radixin, moesin and merlin (ERM) proteins are highly homologous actin-binding proteins that share extensive sequence similarity with each other.
Phosphoinositides in the regulation of actin cortex and cell migration.
Review
New
Itoh et al., Kōbe, Japan. In Biochim Biophys Acta, Jun 2015
It maintains cell shape by linking the actin cortex to the membrane via interactions with Ezrin/Radixin/Moesin (ERM) proteins and class I myosins.
Regulation of spermatogonial stem cell self-renewal and spermatocyte meiosis by Sertoli cell signaling.
Review
New
Liu et al., Beijing, China. In Reproduction, Apr 2015
Sertoli cell growth factors, such as glial cell line-derived neurotrophic factor (GDNF) and fibroblast growth factor 2 (FGF2), as well as Sertoli cell transcription factors, such as ETS variant 5 (ERM; also known as ETV5), nociceptin, neuregulin 1 (NRG1), and androgen receptor (AR), have been identified as the most important upstream factors that regulate SSC self-renewal and spermatocyte meiosis.
Characterizing gene-gene interactions in a statistical epistasis network of twelve candidate genes for obesity.
Gilbert-Diamond et al., United States. In Biodata Min, 2014
In this study, we aimed to analyze pairwise interactions that are associated with Body Mass Index (BMI) between SNPs from twelve genes robustly associated with obesity (BDNF, ETV5, FAIM2, FTO, GNPDA2, KCTD15, MC4R, MTCH2, NEGR1, SEC16B, SH2B1, and TMEM18).
The ezrin-radixin-moesin family of proteins in the regulation of B-cell immune response.
Review
Gupta et al., Cleveland, United States. In Crit Rev Immunol, 2014
The ezrin-radixin-moesin (ERM) family of proteins plays structural and regulatory roles in the rearrangement of plasma membrane flexibility and protrusions through its members' reversible interaction with cortical actin filaments and the plasma membrane.
ICAM-5: a neuronal dendritic adhesion molecule involved in immune and neuronal functions.
Review
Paetau et al., In Adv Neurobiol, 2013
The external part binds to beta1- and beta2-integrins and the matrix protein vitronectin, whereas its transmembrane domain binds to presenilins and the cytoplasmic domain to alpha-actinin and the ERM family of cytoplasmic proteins.
Identification of transcriptional regulators in the mouse immune system.
Impact
Turley et al., Stanford, United States. In Nat Immunol, 2013
Among the previously unknown regulators, we emphasize the role of ETV5 in the differentiation of γδ T cells.
Intracellular lumen extension requires ERM-1-dependent apical membrane expansion and AQP-8-mediated flux.
Impact
Gobel et al., Boston, United States. In Nat Cell Biol, 2013
Here we show that the cortical membrane organizer ERM-1 is required to expand the intracellular apical/lumenal membrane and its actin undercoat during single-cell Caenorhabditis elegans excretory canal morphogenesis.
Differential expression of moesin in breast cancers and its implication in epithelial-mesenchymal transition.
GeneRIF
Lien et al., Taipei, Taiwan. In Histopathology, 2012
These results offer biological evidence of moesin as an EMT marker, support the association between moesin, Snail and EMT and suggest a role for moesin in breast cancer prognostication.
Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.
GeneRIF
Faundez et al., San Luis Potosí, Mexico. In Proc Natl Acad Sci U S A, 2012
Ano1, ezrin, and moesin/radixin colocalize apically in salivary gland epithelial cells, and overexpression of moesin and Ano1 in HEK cells alters the subcellular localization of both proteins
Activation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an autoinhibitory linker.
GeneRIF
Shaw et al., Bethesda, United States. In J Biol Chem, 2012
Activation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an autoinhibitory linker.
FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation.
GeneRIF
Shinohara et al., Kyoto, Japan. In Development, 2012
Mouse germline stem (GS) cell transfected with an activated form of Map2k1 have upregulated Etv5 and Bcl6b gene expression.
Moesin is a biomarker for the assessment of genotoxic carcinogens in mouse lymphoma.
GeneRIF
Kwon et al., Seoul, South Korea. In Mol Cells, 2012
biomarker for the assessment of genotoxic carcinogens in lymphoma
COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Impact
Dixit et al., San Francisco, United States. In Nature, 2011
The proto-oncogenes ETV1, ETV4 and ETV5 encode transcription factors in the E26 transformation-specific (ETS) family, which includes the most frequently rearranged and overexpressed genes in prostate cancer.
Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation.
Impact
Fuchs et al., New York City, United States. In Nat Cell Biol, 2011
Altered concomitantly are phosphorylated ERM and cortical myosin-IIA, shown in vitro to establish a rigid cortical actomyosin network and elicit critical shape changes.
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