The innate immune signaling system as a regulator of disease resistance and ISR activity against Verticillium dahliae.
Athens, Greece. In Mol Plant Microbe Interact, Feb 2016
Tests with Arabidopsis mutants impaired in several regulators of the early steps of the innate immune responses, including fls2, efr-1, bak1-4, mpk3, mpk6, wrky22 and wrky29 showed that FLS2 and WRKY22 have a central role in the K165-triggered ISR, while EFR1, MPK3 and MPK6 are possible susceptibility factors for V. dahliae and bak1 shows a tolerance phenomenon.
New insights into the activation, interaction partners and possible functions of MK5/PRAK.
Tromsø, Norway. In Front Biosci, Dec 2015
However, since the discovery that MK5 is a bona fide interaction partner of the atypical MAP kinases ERK3 and ERK4 and that this interaction leads to both the activation and subcellular relocalisation of MK5, there has been considerable debate as to the relative roles of these MAPK pathways in mediating the activation and biological functions of MK5.
Cellular reprogramming through mitogen-activated protein kinases.
Halle, Germany. In Front Plant Sci, 2014
In our work, we mimicked in vivo activation of two stress-activated MAPKs, MPK3 and MPK6, through transgenic manipulation of Arabidopsis thaliana and used phosphoproteomics analysis to identify potential novel MAPK substrates.
OXI1 kinase is necessary for oxidative burst-mediated signalling in Arabidopsis.
Oxford, United Kingdom. In Nature, 2004
OXI1 is required for full activation of the mitogen-activated protein kinases (MAPKs) MPK3 and MPK6 after treatment with AOS or elicitor and is necessary for at least two very different AOS-mediated processes: basal resistance to Peronospora parasitica infection, and root hair growth.
MAP kinase signalling cascade in Arabidopsis innate immunity.
Boston, United States. In Nature, 2002
Here we identify a complete plant MAP kinase cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) and WRKY22/WRKY29 transcription factors that function downstream of the flagellin receptor FLS2, a leucine-rich-repeat (LRR) receptor kinase.