zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation.more suppliers
In PLoS ONE, 2010
... chain 3 (LC3), Atg5, Atg7, Beclin-1, caspase 3, caspase 9, PARP, GAPDH, non-phospho- or phospho-MEK1/2 and ERK1/2 were from Cell Signaling Technology, Inc. ...
Targeted Therapy for NSCLC-A Double-edged Sword?
München, Germany. In Anticancer Res, 31 May 2015
Several new drugs targeting not only the EGFR pathways, but also signal transduction cascades involved in angiogenesis and the mitogene-activated extracellular signal-regulated kinase kinase pathways are currently evaluated in phase III clinical trials.
Ginger and its constituents: role in prevention and treatment of gastrointestinal cancer.
Houston, United States. In Gastroenterol Res Pract, Dec 2014
The anticancer activity of ginger is attributed to its ability to modulate several signaling molecules like NF-κB, STAT3, MAPK, PI3K, ERK1/2, Akt, TNF-α, COX-2, cyclin D1, cdk, MMP-9, survivin, cIAP-1, XIAP, Bcl-2, caspases, and other cell growth regulatory proteins.
Soy and Breast Cancer: Focus on Angiogenesis.
More papers using
Košice, Slovakia. In Int J Mol Sci, Dec 2014
Genistein was found to inhibit angiogenesis through regulation of multiple pathways, such as regulation of VEGF, MMPs, EGFR expressions and NF-κB, PI3-K/Akt, ERK1/2 signaling pathways, thereby causing strong antiangiogenic effects.
Nuclear actin dynamics–from form to function.
In PLoS ONE, 2007
... Phospho-specific and nonphospho-specific antibodies against ERK1/2, nonmuscle myosin II, and fluorescein isothiocyanate (FITC)-conjugated goat anti-mouse secondary and anti-FITC–HRP antibodies were obtained from Abcam. DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells
In Molecular Cancer, 2007
... (C19), anti-Fra1(H50), anti-Nrf2 (C10), anti-Bax antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA), anti-p38, anti-p44/42, anti-cfos, anti-cjun, anti-junB, anti-junD from Active Motif, anti-Sirt1 from Biomol, anti-Stat3 ... TOR signaling in growth and metabolism
In Oncogene, 2005
... Anti-phospho Src (Ser-416 and Ser-527), anti-phospho-Akt (Ser-473), anti-phospho-S6 kinase (Thr 389), anti-phospho-RSK (Thr-573), and anti-phospho-Erk1/2 (Thr-202/Tyr-204) antibodies were purchased from Cell Signaling (Beverly, MA) ... Method of preparation of Curcurbitacin IIa as anti-cancer drugs
In British Journal of Cancer, 2005
... PARP, cleaved PARP, Histone H3, STAT3, phospho-STAT3 (tyrosine 705), JAK2, phospho-JAK2 (tyrosine 1007/1008), ERK1/2, and phospho-ERK1/2, were from Cell Signaling (Danvers, MA, USA) ... Functional analysis of PIK3CA gene mutations in human colorectal cancer.
In PLoS ONE, 2004
... anti-phospho-HER2 antibodies were purchased from Upstate Biotechnology, Anti-phospho-EGFR, anti-EGFR, anti-phospho-HER3, anti-phospho-c-Met, anti-phospho-Akt, anti-Akt, anti-PTEN, anti-phospho-ERK1/2, anti-ERK1/2, and mutation-specific (L858R in exon 21 and deletion E746-A750 in exon 19) antibodies were from Cell Signaling Technology, anti-HER3 and anti-c-Met ... Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis
In International Journal of Cell Biology, 2003
... following companies: caveolin-1 (Sigma, Mo, USA; C4490), Akt (Abcam (Cambridge, UK); ab28422), phospho-Akt (Abcam, ab27773), ERK1 (Abcam, ab9363), phospho-ERK (Santa Cruz, ... Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling
In The Journal of Experimental Medicine, 2002
... ERK1/2, phospho-ERK1/2, phospho-MEK1/2, phospho-Raf, phospho-Elk-1, phospho-p90, p38, phospho-p38, JNK, phospho-JNK, phospho-Raf and acetyl-K, phospho-MKK3/6, and MKK3 were purchased from Cell Signaling Technology ... Rhamm−/− fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair
In The Journal of Cell Biology, 1997
... muscle actin (immunohistochemistry), nonimmune IgG (Santa Cruz Biotechnology, Inc.), Ki67 (immunohistochemistry; DakoCytomation), tenascin (immunohistochemistry; Chemicon), phospho-ERK1,2 (immunohistochemistry/Western blot/immunofluorescence; Cell Signaling), CD44 (Western blot/immunofluorescence/blocking; IM7; ... Glycosaminoglycans: Molecular properties, protein interactions, and role in physiological processes
In Stem Cells (Dayton, Ohio), 1990
... (3101), phospho-extracellular signal-regulated kinase (ERK)1/2 (9101), phospho-c-Jun N-terminal kinase (JNK)1/2 (9251), phospho-p38 (9211), SMAD 2 (3102), ERK1/2 (9102), and goat anti-rabbit IgG horseradish peroxidase (HRP)–linked (7074) antibodies were purchased from Cell Signaling Inc ...