zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation.more suppliers
In PLoS ONE, 2010
... chain 3 (LC3), Atg5, Atg7, Beclin-1, caspase 3, caspase 9, PARP, GAPDH, non-phospho- or phospho-MEK1/2 and ERK1/2 were from Cell Signaling Technology, Inc. ...
Computational analysis of signaling patterns in single cells.
Chapel Hill, United States. In Semin Cell Dev Biol, 25 Oct 2014
Thus, computational analysis of single-cell signaling has not only provided new ways to quantify the responses of individual cells, but has helped resolve longstanding questions surrounding many well-studied human signaling proteins including NF-κB, p53, ERK1/2, and CDK2.
The biology of A20-binding inhibitors of NF-kappaB activation (ABINs).
In Adv Exp Med Biol, Dec 2013
Additional ABIN functions have been reported such as inhibition of TNF-induced hepatocyte apoptosis, regulation of HIV-1 replication for ABIN-1, and Tumor Progression Locus 2 (TPL-2)-mediated Extracellular signal-Regulated Kinase (ERK) activation for ABIN-2.
ALK pERKs Up MYCN in Neuroblastoma.
More papers using
Essen, Germany. In Sci Signal, Dec 2013
In this issue of Science Signaling, Umapathy et al. identify the kinase extracellular signal-regulated kinase 5 (ERK5) as a central mediator that enables ALK to boost MYCN expression, and they show that inhibiting ERK5 in concert with ALK reduced neuroblastoma cell viability in vitro and in xenograft tumor models.
Nuclear actin dynamics–from form to function.
In PLoS ONE, 2007
... Phospho-specific and nonphospho-specific antibodies against ERK1/2, nonmuscle myosin II, and fluorescein isothiocyanate (FITC)-conjugated goat anti-mouse secondary and anti-FITC–HRP antibodies were obtained from Abcam. DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells
In Molecular Cancer, 2007
... (C19), anti-Fra1(H50), anti-Nrf2 (C10), anti-Bax antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA), anti-p38, anti-p44/42, anti-cfos, anti-cjun, anti-junB, anti-junD from Active Motif, anti-Sirt1 from Biomol, anti-Stat3 ... TOR signaling in growth and metabolism
In Oncogene, 2005
... Anti-phospho Src (Ser-416 and Ser-527), anti-phospho-Akt (Ser-473), anti-phospho-S6 kinase (Thr 389), anti-phospho-RSK (Thr-573), and anti-phospho-Erk1/2 (Thr-202/Tyr-204) antibodies were purchased from Cell Signaling (Beverly, MA) ... Method of preparation of Curcurbitacin IIa as anti-cancer drugs
In British Journal of Cancer, 2005
... PARP, cleaved PARP, Histone H3, STAT3, phospho-STAT3 (tyrosine 705), JAK2, phospho-JAK2 (tyrosine 1007/1008), ERK1/2, and phospho-ERK1/2, were from Cell Signaling (Danvers, MA, USA) ... Functional analysis of PIK3CA gene mutations in human colorectal cancer.
In PLoS ONE, 2004
... anti-phospho-HER2 antibodies were purchased from Upstate Biotechnology, Anti-phospho-EGFR, anti-EGFR, anti-phospho-HER3, anti-phospho-c-Met, anti-phospho-Akt, anti-Akt, anti-PTEN, anti-phospho-ERK1/2, anti-ERK1/2, and mutation-specific (L858R in exon 21 and deletion E746-A750 in exon 19) antibodies were from Cell Signaling Technology, anti-HER3 and anti-c-Met ... Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis
In International Journal of Cell Biology, 2003
... following companies: caveolin-1 (Sigma, Mo, USA; C4490), Akt (Abcam (Cambridge, UK); ab28422), phospho-Akt (Abcam, ab27773), ERK1 (Abcam, ab9363), phospho-ERK (Santa Cruz, ... Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling
In The Journal of Experimental Medicine, 2002
... ERK1/2, phospho-ERK1/2, phospho-MEK1/2, phospho-Raf, phospho-Elk-1, phospho-p90, p38, phospho-p38, JNK, phospho-JNK, phospho-Raf and acetyl-K, phospho-MKK3/6, and MKK3 were purchased from Cell Signaling Technology ... Rhamm−/− fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair
In The Journal of Cell Biology, 1997
... muscle actin (immunohistochemistry), nonimmune IgG (Santa Cruz Biotechnology, Inc.), Ki67 (immunohistochemistry; DakoCytomation), tenascin (immunohistochemistry; Chemicon), phospho-ERK1,2 (immunohistochemistry/Western blot/immunofluorescence; Cell Signaling), CD44 (Western blot/immunofluorescence/blocking; IM7; ... Glycosaminoglycans: Molecular properties, protein interactions, and role in physiological processes
In Stem Cells (Dayton, Ohio), 1990
... (3101), phospho-extracellular signal-regulated kinase (ERK)1/2 (9101), phospho-c-Jun N-terminal kinase (JNK)1/2 (9251), phospho-p38 (9211), SMAD 2 (3102), ERK1/2 (9102), and goat anti-rabbit IgG horseradish peroxidase (HRP)–linked (7074) antibodies were purchased from Cell Signaling Inc ...