zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation.more suppliers
In PLoS ONE, 2010
... chain 3 (LC3), Atg5, Atg7, Beclin-1, caspase 3, caspase 9, PARP, GAPDH, non-phospho- or phospho-MEK1/2 and ERK1/2 were from Cell Signaling Technology, Inc. ...
Genistein and Cancer: Current Status, Challenges, and Future Directions.
Avellino, Italy. In Adv Nutr, 31 Jul 2015
Targeting caspases, B cell lymphoma 2 (Bcl-2)-associated X protein (Bax), Bcl-2, kinesin-like protein 20A (KIF20A), extracellular signal-regulated kinase 1/2 (ERK1/2), nuclear transcription factor κB (NF-κB), mitogen-activated protein kinase (MAPK), inhibitor of NF-κB (IκB), Wingless and integration 1 β-catenin (Wnt/β-catenin), and phosphoinositide 3 kinase/Akt (PI3K/Akt) signaling pathways may act as the molecular mechanisms of the anticancer, therapeutic effects of genistein.
Targeted Therapy for NSCLC--A Double-edged Sword?
München, Germany. In Anticancer Res, May 2015
Several new drugs targeting not only the EGFR pathways, but also signal transduction cascades involved in angiogenesis and the mitogene-activated extracellular signal-regulated kinase kinase pathways are currently evaluated in phase III clinical trials.
Soy and breast cancer: focus on angiogenesis.
More papers using
Košice, Slovakia. In Int J Mol Sci, Dec 2014
Genistein was found to inhibit angiogenesis through regulation of multiple pathways, such as regulation of VEGF, MMPs, EGFR expressions and NF-κB, PI3-K/Akt, ERK1/2 signaling pathways, thereby causing strong antiangiogenic effects.
Nuclear actin dynamics–from form to function.
In PLoS ONE, 2007
... Phospho-specific and nonphospho-specific antibodies against ERK1/2, nonmuscle myosin II, and fluorescein isothiocyanate (FITC)-conjugated goat anti-mouse secondary and anti-FITC–HRP antibodies were obtained from Abcam. DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells
In Molecular Cancer, 2007
... (C19), anti-Fra1(H50), anti-Nrf2 (C10), anti-Bax antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA), anti-p38, anti-p44/42, anti-cfos, anti-cjun, anti-junB, anti-junD from Active Motif, anti-Sirt1 from Biomol, anti-Stat3 ... TOR signaling in growth and metabolism
In Oncogene, 2005
... Anti-phospho Src (Ser-416 and Ser-527), anti-phospho-Akt (Ser-473), anti-phospho-S6 kinase (Thr 389), anti-phospho-RSK (Thr-573), and anti-phospho-Erk1/2 (Thr-202/Tyr-204) antibodies were purchased from Cell Signaling (Beverly, MA) ... Method of preparation of Curcurbitacin IIa as anti-cancer drugs
In British Journal of Cancer, 2005
... PARP, cleaved PARP, Histone H3, STAT3, phospho-STAT3 (tyrosine 705), JAK2, phospho-JAK2 (tyrosine 1007/1008), ERK1/2, and phospho-ERK1/2, were from Cell Signaling (Danvers, MA, USA) ... Functional analysis of PIK3CA gene mutations in human colorectal cancer.
In PLoS ONE, 2004
... anti-phospho-HER2 antibodies were purchased from Upstate Biotechnology, Anti-phospho-EGFR, anti-EGFR, anti-phospho-HER3, anti-phospho-c-Met, anti-phospho-Akt, anti-Akt, anti-PTEN, anti-phospho-ERK1/2, anti-ERK1/2, and mutation-specific (L858R in exon 21 and deletion E746-A750 in exon 19) antibodies were from Cell Signaling Technology, anti-HER3 and anti-c-Met ... Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis
In International Journal of Cell Biology, 2003
... following companies: caveolin-1 (Sigma, Mo, USA; C4490), Akt (Abcam (Cambridge, UK); ab28422), phospho-Akt (Abcam, ab27773), ERK1 (Abcam, ab9363), phospho-ERK (Santa Cruz, ... Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling
In The Journal of Experimental Medicine, 2002
... ERK1/2, phospho-ERK1/2, phospho-MEK1/2, phospho-Raf, phospho-Elk-1, phospho-p90, p38, phospho-p38, JNK, phospho-JNK, phospho-Raf and acetyl-K, phospho-MKK3/6, and MKK3 were purchased from Cell Signaling Technology ... Rhamm−/− fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair
In The Journal of Cell Biology, 1997
... muscle actin (immunohistochemistry), nonimmune IgG (Santa Cruz Biotechnology, Inc.), Ki67 (immunohistochemistry; DakoCytomation), tenascin (immunohistochemistry; Chemicon), phospho-ERK1,2 (immunohistochemistry/Western blot/immunofluorescence; Cell Signaling), CD44 (Western blot/immunofluorescence/blocking; IM7; ... Glycosaminoglycans: Molecular properties, protein interactions, and role in physiological processes
In Stem Cells (Dayton, Ohio), 1990
... (3101), phospho-extracellular signal-regulated kinase (ERK)1/2 (9101), phospho-c-Jun N-terminal kinase (JNK)1/2 (9251), phospho-p38 (9211), SMAD 2 (3102), ERK1/2 (9102), and goat anti-rabbit IgG horseradish peroxidase (HRP)–linked (7074) antibodies were purchased from Cell Signaling Inc ...