A PAK-activated linker for EGFR and FAKmore suppliers
In OncoTargets and therapy, 2009
... rabbit anti-human p130cas, rabbit anti-human p130cas(Y410) phosphorylation, rabbit anti-human ERK (ERK1 + ERK2), and rabbit anti-human ERK general phosphorylation (T185 + Y187 + T202 + Y204) antibodies were purchased from Abcam (Cambridge, MA) ...
Regulation of RAF protein kinases in ERK signalling.
Montréal, Canada. In Nat Rev Mol Cell Biol, 31 May 2015
The fact that current RAF inhibitors unexpectedly induce ERK signalling by stimulating RAF dimerization also calls for a deeper structural characterization of this family of kinases.
A lactate-induced response to hypoxia.
Taejŏn, South Korea. In Cell, 23 May 2015
The stabilized NDRG3 protein binds c-Raf to mediate hypoxia-induced activation of Raf-ERK pathway, promoting angiogenesis and cell growth.
Biliverdin reductase: a target for cancer therapy?
More papers using
Rochester, United States. In Front Pharmacol, Dec 2014
In this review, we summarize the recent developments that define the pro-growth activities of BVR, particularly with respect to its input into the MAPK signaling pathway and present evidence that BVR-based peptides inhibit activation of protein kinases, including MEK, PKCδ, and ERK as well as downstream targets including Elk1 and iNOS, and thus offers a credible novel approach to reduce cancer cell proliferation.
The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma
In British Journal of Cancer, 2005
... p4EBP1, vascular endothelial growth factor receptor (VEGF), VEGFR-1, mTOR, PLD1, PLD2, S6K, pS6K, MEK, pMEK, ERK, pERK, ERα, and ERβ were purchased from Abcam (Cambridge, MA, USA) ... HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells
In The Journal of Cell Biology, 2005
... antibodies against β-gal, CD31 (goat), CD144 (mouse), HDAC1, p21, p53, p-AktThr308, Akt1/2 (goat), pERK42/44, and ERK2 were obtained from Santa Cruz Biotechnology, Inc.; antibodies against eNOS, ... The comet assay: a method to measure DNA damage in individual cells
In Cell Death & Disease, 2005
... H2AX anti-rabbit antibody (pS139) (Epitomics, Burlingame, CA, USA), ERK2 (Santa Cruz, CA, USA), Topo IIα (Enzo Life Sciences, Lörrach, Germany), Topo IIβ antibody (Abcam, Cambridge, MA, USA), p-Chk1 ... Inhibition of mitogen-activated protein kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells.
In Environmental Health Perspectives, 2004
... c-Fos (H-125), β-actin (C-2), phosphorylated extracellular signal-regulated kinase 1/2 (p-ERK1/2; E-4), Egr-1 (588), CTGF (L-20), ERK2 (C-14), ERα (F-10), or GPR30 (N-15), all from Santa Cruz Biotechnology, DBA (Milan, Italy), or ... CD8+ T cells in autoimmunity
In Indian Journal of Human Genetics, 2004
... such as SB203580 (SB) for p38 kinase, SP600125 (SP) for JNK and PD98059 (PD) for ERK were purchased from BIOMOL (Plymouth Meeting, PA, USA) ... Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones
In BMC Neuroscience, 2002
... Biologicals (Littleton, CO, USA), rabbit anti-phospho-ERK1/2 antibody from Cell Signaling Technology (Beverly, MA, USA), mouse anti-ERK2 antibody from BD Transduction Laboratories (Becton Dickinson and Company, Franklin Lakes, ... Spatiotemporal Dynamics of CREB Phosphorylation: Transient versus Sustained Phosphorylation in the Developing Striatum.
In PLoS ONE, 1995
... anti-p-Akt1 (Ser47, sc-7985-R), anti-p-JNK (Thr183/Tyr185, sc-12882-R), anti-JNK (sc-572), anti-Actin (sc-10731), goat polyclonal anti-Akt (sc-7126), and anti-ERK (sc-94-G) antibodies were acquired from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...