A PAK-activated linker for EGFR and FAKmore suppliers
In OncoTargets and therapy, 2009
... rabbit anti-human p130cas, rabbit anti-human p130cas(Y410) phosphorylation, rabbit anti-human ERK (ERK1 + ERK2), and rabbit anti-human ERK general phosphorylation (T185 + Y187 + T202 + Y204) antibodies were purchased from Abcam (Cambridge, MA) ...
MEK inhibition in non-small cell lung cancer.
Chapel Hill, United States. In Lung Cancer, 16 Oct 2014
KRAS mutations result in the activation of the RAF-MEK-ERK pathway, and agents that target RAF-MEK-ERK pathways have been investigated in KRAS mutant NSCLC.
Insulin resistance in Alzheimer's disease.
Galveston, United States. In Neurobiol Dis, 16 Oct 2014
Since insulin has a key role in learning and memory as well as directly regulating ERK, a kinase required for the type of learning and memory compromised in early Alzheimer's disease (AD), insulin resistance has been identified as a major risk factor for the onset of AD.
The biology of A20-binding inhibitors of NF-kappaB activation (ABINs).
More papers using
In Adv Exp Med Biol, Dec 2013
Additional ABIN functions have been reported such as inhibition of TNF-induced hepatocyte apoptosis, regulation of HIV-1 replication for ABIN-1, and Tumor Progression Locus 2 (TPL-2)-mediated Extracellular signal-Regulated Kinase (ERK) activation for ABIN-2.
The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma
In British Journal of Cancer, 2005
... p4EBP1, vascular endothelial growth factor receptor (VEGF), VEGFR-1, mTOR, PLD1, PLD2, S6K, pS6K, MEK, pMEK, ERK, pERK, ERα, and ERβ were purchased from Abcam (Cambridge, MA, USA) ... HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells
In The Journal of Cell Biology, 2005
... antibodies against β-gal, CD31 (goat), CD144 (mouse), HDAC1, p21, p53, p-AktThr308, Akt1/2 (goat), pERK42/44, and ERK2 were obtained from Santa Cruz Biotechnology, Inc.; antibodies against eNOS, ... The comet assay: a method to measure DNA damage in individual cells
In Cell Death & Disease, 2005
... H2AX anti-rabbit antibody (pS139) (Epitomics, Burlingame, CA, USA), ERK2 (Santa Cruz, CA, USA), Topo IIα (Enzo Life Sciences, Lörrach, Germany), Topo IIβ antibody (Abcam, Cambridge, MA, USA), p-Chk1 ... Inhibition of mitogen-activated protein kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells.
In Environmental Health Perspectives, 2004
... c-Fos (H-125), β-actin (C-2), phosphorylated extracellular signal-regulated kinase 1/2 (p-ERK1/2; E-4), Egr-1 (588), CTGF (L-20), ERK2 (C-14), ERα (F-10), or GPR30 (N-15), all from Santa Cruz Biotechnology, DBA (Milan, Italy), or ... CD8+ T cells in autoimmunity
In Indian Journal of Human Genetics, 2004
... such as SB203580 (SB) for p38 kinase, SP600125 (SP) for JNK and PD98059 (PD) for ERK were purchased from BIOMOL (Plymouth Meeting, PA, USA) ... Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones
In BMC Neuroscience, 2002
... Biologicals (Littleton, CO, USA), rabbit anti-phospho-ERK1/2 antibody from Cell Signaling Technology (Beverly, MA, USA), mouse anti-ERK2 antibody from BD Transduction Laboratories (Becton Dickinson and Company, Franklin Lakes, ... Spatiotemporal Dynamics of CREB Phosphorylation: Transient versus Sustained Phosphorylation in the Developing Striatum.
In PLoS ONE, 1995
... anti-p-Akt1 (Ser47, sc-7985-R), anti-p-JNK (Thr183/Tyr185, sc-12882-R), anti-JNK (sc-572), anti-Actin (sc-10731), goat polyclonal anti-Akt (sc-7126), and anti-ERK (sc-94-G) antibodies were acquired from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...