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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 31 Oct 2014.

Mitogen-activated protein kinase 1

ERK, Mitogen-Activated Protein Kinase 1, ERK2
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Akt, MAPK, V1a, p38, CAN
Papers using ERK antibodies
Galectin-3 mediates cross-talk between K-Ras and Let-7c tumor supressor micro RNA
Supplier
Sarkar Fazlul H., In PLoS ONE, 2010
... Anti-Ras monoclonal antibody, anti-RalA monoclonal antibody, anti-phospho-AKT and anti-phospho-ERK antibodies were from Cell Signaling Technology, Inc ...
A PAK-activated linker for EGFR and FAK
Supplier
Xiaozhong Wang et al., In OncoTargets and therapy, 2009
... rabbit anti-human p130cas, rabbit anti-human p130cas(Y410) phosphorylation, rabbit anti-human ERK (ERK1 + ERK2), and rabbit anti-human ERK general phosphorylation (T185 + Y187 + T202 + Y204) antibodies were purchased from Abcam (Cambridge, MA) ...
Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells.
Supplier
Rishi Arun, In PLoS ONE, 2009
... TX); ERβ (Oncogene Research Products, San Diego, CA); phospho-p42/p44 ERK/MAPK (Cell Signaling, Beverly, MA); ERK1, ERK2, (Santa Cruz Biotechnology, Santa Cruz, CA); GPR30 ...
Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells.
Supplier
Hotchin Neil A., In PLoS ONE, 2009
... Rabbit anti-ERK (#9102) and mouse anti-phospho-ERK (#9106) were purchased from Cell Signaling (Danvers, USA), fluorophor-labelled phalloidin ...
Circulating mitochondrial DAMPs cause inflammatory responses to injury
Supplier
Lotze Michael T. et al., In The Journal of Cell Biology, 2009
... The antibodies to caspase-3, cleaved caspase-3, cleaved PARP, GFP, Bcl-2, p-ERK (Thr202/Tyr204), and ERK were obtained from Cell Signaling Technology ...
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Papers on ERK
Serine/Threonine-Protein Kinase PFTK1 Modulates Oligodendrocyte Differentiation via PI3K/AKT Pathway.
New
Feng et al., Xinxiang, China. In J Mol Neurosci, 30 Nov 2014
Significantly, PFTK1 silencing leads to the activation of PI3K/AKT pathway, but no activation of MAPK/ERK pathway.
miRNA-130b is required for the ERK/FOXM1 pathway activation-mediated protective effects of isosorbide dinitrate against mesenchymal stem cell senescence induced by high glucose.
New
Ge et al., Shanghai, China. In Int J Mol Med, 29 Nov 2014
It was also found that the senescent MSCs (induced by HG glucose) exhibited a marked downregulation in ERK activity and forkhead box M1 (FOXM1) expression, which was reversed by ISDN preconditioning.
Chelidonium majus L. extract induces apoptosis through caspase activity via MAPK-independent NF-κB signaling in human epidermoid carcinoma A431 cells.
New
Kim et al., Taegu, South Korea. In Oncol Rep, 23 Nov 2014
C. majus L. extract not only inhibited NF-κB activation, but it also activated p38 MAPK and MEK/ERK signaling.
Conditional density-based analysis of T cell signaling in single-cell data.
New
Impact
Nolan et al., New York City, United States. In Science, 23 Nov 2014
We validated our characterization on mice lacking the extracellular-regulated MAP kinase (ERK2), which showed stronger influence of pERK on pS6 (phosphorylated-ribosomal protein S6), in naïve cells compared to antigen-exposed cells, as predicted.
Suppression of Feedback Loops Mediated by PI3K/mTOR Induces Multiple Overactivation of Compensatory Pathways: An Unintended Consequence Leading to Drug Resistance.
Review
New
Sinnet-Smith et al., Los Angeles, United States. In Mol Cancer Ther, 16 Nov 2014
Suppression of these feedback loops causes overactivation of upstream pathways, including PI3K, AKT, and ERK that potentially oppose the antiproliferative effects of mTOR inhibitors and lead to drug resistance.
Naturally Occurring Neomorphic PIK3R1 Mutations Activate the MAPK Pathway, Dictating Therapeutic Response to MAPK Pathway Inhibitors.
New
Impact
Mills et al., Houston, United States. In Cancer Cell, 13 Nov 2014
Consistent with the response to inhibitors, PIK3R1(R348∗) and PIK3R1(L370fs) unexpectedly increase JNK and ERK phosphorylation.
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.
New
Impact
Zender et al., Tübingen, Germany. In Nat Med, 31 Oct 2014
Both shRNA-mediated and pharmacological silencing of Mapk14 (p38α) were found to sensitize mouse HCC to sorafenib therapy and prolong survival by abrogating Mapk14-dependent activation of Mek-Erk and Atf2 signaling.
A new tumor suppressor role for the Notch pathway in bladder cancer.
New
Impact
Klinakis et al., Athens, Greece. In Nat Med, 31 Oct 2014
We show that Notch activation in bladder cancer cells suppresses proliferation both in vitro and in vivo by directly upregulating dual-specificity phosphatases (DUSPs), thus reducing the phosphorylation of ERK1 and ERK2 (ERK1/2).
A8, An Anti-uPA Agonistic Antibody, Promotes Metastasis of Cancer Cells Via ERK Pathway.
New
Park et al., Pusan, South Korea. In Monoclon Antib Immunodiagn Immunother, 31 Oct 2014
A8 increased ERK phosphorylation, and enhanced migration was blocked by U0126, but not by LY0294002, SB2203580, and SP600125.
Metabolic Respiration Induces AMPK- and Ire1p-Dependent Activation of the p38-Type HOG MAPK Pathway.
New
Cullen et al., Buffalo, United States. In Plos Genet, 31 Oct 2014
Thus, an evolutionarily conserved regulatory axis links metabolic respiration and AMPK to Ire1p, which regulates a differentiation response involving the modulated activity of ERK and p38 MAPK pathways.
MEK inhibition in non-small cell lung cancer.
Review
New
Johnson et al., Chapel Hill, United States. In Lung Cancer, 16 Oct 2014
KRAS mutations result in the activation of the RAF-MEK-ERK pathway, and agents that target RAF-MEK-ERK pathways have been investigated in KRAS mutant NSCLC.
Insulin resistance in Alzheimer's disease.
Review
New
Denner et al., Galveston, United States. In Neurobiol Dis, 16 Oct 2014
Since insulin has a key role in learning and memory as well as directly regulating ERK, a kinase required for the type of learning and memory compromised in early Alzheimer's disease (AD), insulin resistance has been identified as a major risk factor for the onset of AD.
Resetting transcription factor control circuitry toward ground-state pluripotency in human.
New
Impact
Smith et al., Cambridge, United Kingdom. In Cell, 11 Oct 2014
Inhibition of ERK and protein kinase C sustains a transgene-independent rewired state.
Mnk kinase pathway: Cellular functions and biological outcomes.
Review
New
Platanias et al., Houston, United States. In World J Biol Chem, 26 Sep 2014
The mitogen-activated protein kinase (MAPK) interacting protein kinases 1 and 2 (Mnk1 and Mnk2) play important roles in controlling signals involved in mRNA translation.
The biology of A20-binding inhibitors of NF-kappaB activation (ABINs).
Review
New
Beyaert et al., In Adv Exp Med Biol, Dec 2013
Additional ABIN functions have been reported such as inhibition of TNF-induced hepatocyte apoptosis, regulation of HIV-1 replication for ABIN-1, and Tumor Progression Locus 2 (TPL-2)-mediated Extracellular signal-Regulated Kinase (ERK) activation for ABIN-2.
The role of Ras-ERK-IL-1β signaling pathway in upregulation of elastin expression by human coronary artery smooth muscle cells cultured in 3D scaffolds.
GeneRIF
Mequanint et al., London, Canada. In Biomaterials, 2012
endogenous IL-1beta play a role in elastin gene upregulation and this upregulation is mediated by the Ras-ERK1/2 pathway in 3D cultures
Extracellular signal-regulated kinase 1/2 signaling promotes oligodendrocyte myelination in vitro.
GeneRIF
Murray et al., Melbourne, Australia. In J Neurochem, 2012
Erk1/2 signaling within oligodendrocytes exerts an important and direct effect to promote myelination.
A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics.
GeneRIF
Sheikh et al., San Diego, United States. In J Biol Chem, 2012
A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics.
ERK1/2 activation is a therapeutic target in age-related macular degeneration.
GeneRIF
Ambati et al., Lexington, United States. In Proc Natl Acad Sci U S A, 2012
ERK1/2 have roles in the pathogenesis of GA, a late stage of age-related macular degeneration
ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination.
GeneRIF
Bansal et al., Farmington, United States. In J Neurosci, 2012
These studies suggest that the predominant role of ERK1/ERK2 signaling in vivo is in promoting rapid myelin growth to increase its thickness, subsequent to oligodendrocyte differentiation and the initiation of myelination.
More papers using ERK antibodies
Pseudohypoparathyroidism and GNAS epigenetic defects: clinical evaluation of Albright hereditary osteodystrophy and molecular analysis in 40 patients
Supplier
Friedman Peter A et al., In Journal of Bone and Mineral Research, 2009
... The phosphorylated ERK1/2 and total ERK antibodies were obtained from Cell Signaling Technology (Danvers, MA, USA) ...
Glucose activates prenyltransferases in pancreatic islet beta-cells
Supplier
Koch Brandon J. et al., In Diabetes, 2009
... Antibodies against phospho-p44/42 ERK kinase (Thr202/Tyr204) and total p44/42 ERK kinase were from Cell Signaling Technology (Danvers, MA) ...
PKC-1 acts with the ERK MAPK signaling pathway to regulate Caenorhabditis elegans mechanosensory response
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Hou Ya-yi et al., In Journal of Biomedical Science, 2009
... PD98059 (selective inhibitor of ERK signaling pathway) and CGP53353 (selective inhibitor of PKCβII signaling pathway) were obtained from TOCRIS Bioscience Company (Bristol, UK) ...
Systems biology of growth factor-induced receptor endocytosis
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Polo Simona et al., In Molecular Systems Biology, 2008
... Upstate) polyclonal anti-EphA2 (clone C-20, Santa Cruz), polyclonal anti-SLC3A2 (H-300, Santa Cruz), monoclonal anti-Cbl (BD), anti-phospho-ERK (Cell Signaling), anti-phospho-AKT (Cell Signaling) and ...
beta-1 and beta-2, but not alpha-1 and alpha-2, adrenoceptor blockade delays rat cutaneous wound healing
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Béliveau Richard et al., In OncoTargets and therapy, 2008
... against phospho-ERK, Akt and phospho-Akt were purchased from Cell Signalling (Danvers, MA, USA), the polyclonal anti-ERK antibody was from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Estrogen receptor-alpha (ER-alpha) suppresses expression of its variant ER-alpha 36
Supplier
Wang Zhao-Yi et al., In Oncogene, 2008
... Phospho-EGFR and -Src antibodies, EGFR, Src and Shc antibodies, anti-phospho-p44/42 ERK (Thr202/Tyr204) antibody and anti-p44/42 ERK antibody were all purchased from Cell Signaling Technology (Boston, MA) ...
A solution for stripping antibodies from polyvinylidene fluoride immunoblots for multiple reprobing.
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Brandner Johanna M., In PLoS ONE, 2008
... or Alexa594-conjugated secondary antibodies (Molecular Probes); β-tubulin, cyclin D1, PCNA, RACK-1, transglutaminase 1 (Tgase 1), ERK-1, p(T202/Y204)-ERK1/ERK2 and HRP-conjugated secondary antibodies (Santa Cruz Biotechnology); PKC isotypes (BD Biosciences); ...
Rac1 is required for cardiomyocyte apoptosis during hyperglycemia
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Kowluru Anjaneyulu et al., In Diabetes, 2008
... Antisera for caspase-3, JNK1/2, and extracellular signal–related kinase (ERK) 1/2 were from Cell Signaling Technology (Boston, MA) ...
Eph receptors in breast cancer: roles in tumor promotion and tumor suppression
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Debinski Waldemar, In PLoS ONE, 2007
... anti-β-tubulin (Santa Cruz Biotechnologies), and anti-PCNA (NeoMarkers), anti-Myc, anti-cleaved casepase 3, anti-pThr308AKT, anti-pSer473AKT, anti-pERK, anti-AKT, anti-ERK (Cell Signaling Technologies) ...
Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury
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Combs Colin K et al., In Journal of Neuroinflammation, 2007
... Anti-α2 integrin antibody, anti-α1 integrin antibody, anti-β1 integrin antibody, anti-phospho-ERK, anti-ERK2 antibody, and Protein A/G PLUS-Agarose beads were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms
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Kundu Gopal C et al., In Molecular Cancer, 2007
... Rabbit polyclonal anti-ICAM-1, goat polyclonal anti-actin, mouse monoclonal anti-p70S6 kinase, mouse anti-p-ERK1/2 and rabbit anti-ERK2 antibodies were purchased from Santa Cruz Biotechnology.
Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins
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Streuli Charles H et al., In Breast Cancer Research : BCR, 2007
... 2F1) and calnexin (Bioquote Ltd, York, UK); Ki67-FITC (BD Transduction Labs, Franklin Lakes, NJ, USA); phospho-Erk and oestrogen receptor alpha (Cell Signaling, Beverly, MA, USA); Cytokeratin ...
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals.
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Blachier François, In PLoS ONE, 2007
... Phospho-ERK antibody was obtained from Cell Signaling Technology (cat#9106) ...
Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells.
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Roy Craig R., In PLoS Pathogens, 2006
... anti-p65/RelA and bovine anti-sheep-HRP (all from Santa Cruz Biotechnology); rabbit anti-Bik, rabbit anti-vimentin, and mouse anti-Erk 1/2 (all from Cell Signaling Technology); goat anti-mouse-HRP and ...
Abundance, complexation, and trafficking of Wnt/beta-catenin signaling elements in response to Wnt3a
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Malbon Craig C et al., In Journal of Molecular Signaling, 2006
... Mouse anti-AKAP5, anti-pERK monoclonal antibody, rabbit anti-ERK, goat anti-mouse IgG-HRP, and goat anti-rat IgG-HRP were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells
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Hunter Tony et al., In The Journal of Cell Biology, 2006
... Antibodies used were c-Fos, vimentin, MLC2 (sc-28329 and sc-15370), and ERK2 (Santa Cruz Biotechnology, Inc.); α ...
A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions
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Alaoui-Jamali M A et al., In British Journal of Cancer, 2006
... Antibodies to Akt1, phospho-Akt (Ser473), ERK1/2, and phospho-ERK (Tyr202/Tyr204) were from Cell Signaling Technology (Beverly, MA, USA) ...
A role for the mitogen-activated protein kinase kinase kinase 1 in epithelial wound healing.
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Connon Che John, In PLoS ONE, 2005
... The chemical inhibitors for JNK (SP600125), p38 (SB202190), ERK (PD98059) were obtained from Calbiochem (Gibbstown, NJ); and the inhibitor for IKKβ (TPCA-1) was from Tocris Bioscience (Ellisville, Missouri) ...
The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma
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Rosengren R J et al., In British Journal of Cancer, 2005
... p4EBP1, vascular endothelial growth factor receptor (VEGF), VEGFR-1, mTOR, PLD1, PLD2, S6K, pS6K, MEK, pMEK, ERK, pERK, ERα, and ERβ were purchased from Abcam (Cambridge, MA, USA) ...
Adaptation of enterocytic Caco-2 cells to glucose modulates triacylglycerol-rich lipoprotein secretion through triacylglycerol targeting into the endoplasmic reticulum lumen.
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Fox Debbie, In PLoS ONE, 2005
... (BD Transduction Laboratories), rabbit polyclonal anti-SR-BI (Novus 400-104), sheep polyclonal anti-PLAP (ABDSerotec 0300-1909), rabbit polyclonal anti-ERK (Cell Signaling), rabbit polyclonal anti-P-ERK (Thr202/Tyr204, ...
HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells
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Xu Qingbo et al., In The Journal of Cell Biology, 2005
... antibodies against β-gal, CD31 (goat), CD144 (mouse), HDAC1, p21, p53, p-AktThr308, Akt1/2 (goat), pERK42/44, and ERK2 were obtained from Santa Cruz Biotechnology, Inc.; antibodies against eNOS, ...
Phospholipase D1 regulates cell migration in a lipase activity-independent manner.
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Chu Charleen T., In PLoS ONE, 2005
... Polyclonal anti-pAMPK antibody (Thr-172), anti-pERK (Thr-202/Tyr-204) antibody and anti-ERK antibody were purchased from Cell Signaling.
Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells
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Saikumar Pothana et al., In Oncogene, 2005
... Antibodies to phospho-p38, phospho-SAPK, phospho-ERK were from Cell signaling Technology (Danvers, MA) ...
Oncogenic PI3K and its role in cancer
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Nie Daotai, In PLoS ONE, 2005
... Antibodies were obtained from following commercial sources: anti-Par-4, anti-MMP-2, anti-Akt, anti-ERK, and anti-TIMP-1 from Santa Cruz Biotechnology (Santa Cruz, CA), anti-p-Akt ...
Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells.
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Gullberg Donald, In PLoS ONE, 2005
... c-Jun, poly(ADP-ribose) polymerase (PARP), and ubiquitin (all from Cell Signaling Technology, Inc., Danvers, MA); T202/Y204-phosphorylated Erk (Santa Cruz Biotechnology, Santa Cruz, CA) ...
Inactivation of MAPK in mature oocytes triggers progression into mitosis via a Ca2+-dependent pathway but without completion of S phase
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Whitaker M. et al., In Developmental Biology, 2005
... U0126, polyclonal anti-ERK and anti-active ERK antibodies were obtained from Promega; MBP and monoclonal anti-active ERK antibody from New England Biolabs; Hoechst 33342 dye from ...
Regulation of angiogenesis and tumor growth by p110 alpha and AKT1 via VEGF expression.
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Navarro Alfons, In PLoS ONE, 2005
... Antibodies against ERK2 were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
The anti-angiogenic peptide anginex disrupts the cell membrane
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Yang K-D et al., In Cell Death & Disease, 2005
... Antibodies to phospho-histone H2AX (Ser139), phospho-Raf-1, Raf-1, phospho-p42/44 ERK, and p42/44 ERK were purchased from Cell Signaling Technology (Beverly, MA, USA) ...
The comet assay: a method to measure DNA damage in individual cells
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Fritz G et al., In Cell Death & Disease, 2005
... H2AX anti-rabbit antibody (pS139) (Epitomics, Burlingame, CA, USA), ERK2 (Santa Cruz, CA, USA), Topo IIα (Enzo Life Sciences, Lörrach, Germany), Topo IIβ antibody (Abcam, Cambridge, MA, USA), p-Chk1 ...
Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1.
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Lebedeva Irina V., In PLoS ONE, 2005
... The ERK inhibitor PD98059 (Merck KGaA) was used in ...
Mitogen activated protein (MAP) kinases: development of ATP and non-ATP dependent inhibitors 2
Supplier
Ong Siew H et al., In Journal of Molecular Signaling, 2005
... α-Flag (M2) and α-phospho-p38 were from Sigma, α-phospho-Erk was from Cell Signaling Technology, α-HA (12CA5) was ...
Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts
Supplier
Chen Hong-Chen et al., In Journal of Biomedical Science, 2004
... Polyclonal anti-Met (C12), anti-EGFR (1005), and anti-ERK were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain
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Combs Colin K et al., In Journal of Neuroinflammation, 2004
... Anti-Lyn, anti-Syk, anti-COX-2, anti-phospho-ERK, anti-ERK2 antibody, horseradish peroxidase conjugated secondary antibodies, and protein A/G PLUS-Agarose beads were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-κB activation
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Bianchi Marco E. et al., In The Journal of Cell Biology, 2004
... U0126 and antibodies against IκBα, pIκBα, ERK, and phospho-ERK were obtained from Cell Signaling Technology ...
Src kinase regulation by phosphorylation and dephosphorylation
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Migliaccio Antimo, In PLoS ONE, 2004
... antibodies, EGFR and Src antibodies, anti-phospho-p44/42 ERK (Thr202/Tyr204) (197G2) mouse monoclonal antibody (mAb) and anti-p44/42 ERK (137F5) rabbit mAb were purchased from Cell Signaling Technology (Boston, MA) ...
Inhibition of mitogen-activated protein kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells.
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Maggiolini Marcello et al., In Environmental Health Perspectives, 2004
... c-Fos (H-125), β-actin (C-2), phosphorylated extracellular signal-regulated kinase 1/2 (p-ERK1/2; E-4), Egr-1 (588), CTGF (L-20), ERK2 (C-14), ERα (F-10), or GPR30 (N-15), all from Santa Cruz Biotechnology, DBA (Milan, Italy), or ...
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
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Borthwick Lee A. et al., In The American Journal of Pathology, 2004
... (9252; Cell Signaling), phospho-JNK-1/2 (4668; Cell Signaling), p38 (sc-7149; Santa Cruz Biotechnology), phospho-p38 (ab4822; Abcam), ERK-1/2 (4695; Cell Signaling), phospho-ERK-1/2 (4370; Cell Signaling), ...
Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB.
Supplier
Anderson Kurt I., In PLoS ONE, 2004
... ERK2 antibody used in this study was obtained from Santa Cruz (Heidelberg, Germany), antibody for phosphorylated IκBα (p-IκBα) originated from New England Biolabs (Frankfurt am Main, Germany) ...
CD8+ T cells in autoimmunity
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Chakraborty Nitya G. et al., In Indian Journal of Human Genetics, 2004
... such as SB203580 (SB) for p38 kinase, SP600125 (SP) for JNK and PD98059 (PD) for ERK were purchased from BIOMOL (Plymouth Meeting, PA, USA) ...
Fibronectin stimulates human lung carcinoma cell proliferation by suppressing p21 gene expression via signals involving Erk and Rho kinase
Supplier
Hynes Nancy E et al., In Breast Cancer Research : BCR, 2004
... (OP64-100UG) (Oncogene Research Products, Cambridge, MA, USA); ERK and P-ERK (Thr202/Tyr204) (Cell Signaling Technology, Danvers, MA, USA); ...
Diallyl trisulfide-induced G(2)-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc 25 C
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Antosiewicz Jedrzej et al., In European Journal of Nutrition, 2004
... The antibodies against ERK, P-ERK, were from Cell Signaling Technology, and actin was ...
Membrane estrogen receptor-alpha levels in MCF-7 breast cancer cells predict cAMP and proliferation responses
Supplier
Watson Cheryl S. et al., In Environmental Health Perspectives, 2004
... We purchased the phosphorylated ERK (pERK) antibody (Ab) used in the ERK phosphorylation studies from Cell Signaling Technology (Danvers, MA) ...
PPARγ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
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Ballock R. Tracy et al., In PPAR Research, 2003
... The MAPK/ERK inhibitor PD98059 (20 μM, Cell Signaling Technology, Danvers, MA) and ...
Inefficient replication of Listeria innocua in the cytosol of mammalian cells.
Supplier
Cossart Pascale, In PLoS Pathogens, 2003
... The rabbit anti-p-p44/42 (phospho-Erk) and the mouse anti-p44/42 (total-Erk) was from Cell Signaling Technology (Beverly, MA, USA) ...
Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis
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Auberger Patrick et al., In Oncotarget, 2003
... Anti-phosphotyrosine (P-Tyr), anti-PARP, anti-PKCα, anti-PKCβ, anti-PKCγ, anti-phospho-ERK, and peroxydase-conjugated anti-rabbit antibodies were purchased from Cell Signaling Technology (Beverly, MA, USA) ...
The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL–C3G-mediated activation of Rap1
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Billadeau Daniel D. et al., In The Journal of Cell Biology, 2003
... The antibodies for phospho-CrkL (Y207), phospho-PLCγ1 (Y783), phospho-Pak1 Thr423 (Mst1 Thr183), total Mst1, and Erk were obtained from Cell Signaling Technology ...
Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones
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Panula Pertti et al., In BMC Neuroscience, 2002
... Biologicals (Littleton, CO, USA), rabbit anti-phospho-ERK1/2 antibody from Cell Signaling Technology (Beverly, MA, USA), mouse anti-ERK2 antibody from BD Transduction Laboratories (Becton Dickinson and Company, Franklin Lakes, ...
Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells
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Cho Myung Haing et al., In Journal of Veterinary Science, 2002
... Anti-Bid, anti-Bax, anti-Bcl-xL, anti-Akt, anti-phospho-Akt Thr-308, Ser-473, anti-ERK and anti-phospho-ERK antibodies for Western blot analysis were purchased from Santa Cruz Biotechnology (USA) ...
Farnesyltransferase inhibitors as anticancer agents: current status
Supplier
Danesi R et al., In British Journal of Cancer, 2002
... and anti-p42MAPK/ERK2 rabbit polyclonal antibodies were from Santa Cruz Biotechnology Inc ...
Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPARγ) agonists and 9-cis-retinoic acid
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Ramji Dipak P. et al., In The International Journal of Biochemistry & Cell Biology, 2002
... Human recombinant TGF-β1 was from Peprotech, validated Smad-2, c-Jun and extracellular signal-regulated kinase (ERK) 1/2 small interfering RNA (siRNA) was from Qiagen and validated Smad-3 and ...
Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth
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Meakin Susan O. et al., In The Journal of Cell Biology, 2001
... used were EGFR and GFP (Santa Cruz Biotechnology, Inc.), phospho-p44/42 MapK (New England Biolabs, Inc.), Erk2 (BD Biosciences), and RC20 (Transduction Laboratories) ...
Mitogen-activated protein kinases and nuclear factor-κB regulate Helicobacter pylori-mediated interleukin-8 release from macrophages
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Arakawa Tetsuo et al., In Journal of Clinical Biochemistry and Nutrition, 2001
... IκB-α was purchased from Cell Signaling Technology (Danvers, MA), and antibody for ERK2 and phosphorylated ERK2 was purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Influence of the structural diversity of data sets on the statistical quality of three-dimensional quantitative structure-activity relationship (3D-QSAR) models: predicting the estrogenic activity of xenoestrogens
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Watson Cheryl S. et al., In Environmental Health Perspectives, 2001
... Phospho-p44/42 ERK (pERK) monoclonal antibody (Ab), anti-mouse horseradish peroxidase–linked Ab, and lysis buffer were obtained from Cell Signaling Technology (Beverly, MA) ...
c-myc is a downstream target of the Smad pathway
Supplier
Datta P K et al., In British Journal of Cancer, 2001
... , anti-p53, anti-Cdk2, anti-Cdk4, anti-Cyclin D1, ERK and anti-Rb antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
The Helicobacter pylori Vacuolating Toxin Inhibits T Cell Activation by Two Independent Mechanisms
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Baldari Cosima T. et al., In The Journal of Experimental Medicine, 2000
... active forms of p38, Erk1/2, and MKK 3/6 were from Cell Signaling Technology, anti-p38 and anti-Erk antibodies were from Santa Cruz Biotechnology, antiphosphotyrosine mAb, anti–cyclooxygenase (COX)-2 ...
The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gelatinase-associated lipocalin (NGAL). Modulation of MMP-9 activity by NGAL.
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Gullberg Donald, In PLoS ONE, 2000
... Western Blotting Luminol Reagent, HRP-conjugated donkey anti-goat secondary antibody, rabbit polyclonal antibodies against human ERK2, PKC βI, βII, δ and goat polyclonal antibody against human PKCθ were from Santa Cruz Biotechnology.
Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53
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Price Brendan D et al., In BMC Cell Biology, 2000
... (2 μg; measured using Bio-Rad Protein assay Kit, Biorad, CA) was incubated with MAP kinase (Erk2, 10 Units, New England Biolabs, MA), Protein Kinase A (Catalytic ...
The B Cell Antigen Receptor Controls Integrin Activity through Btk and PLCγ2
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Pals Steven T. et al., In The Journal of Experimental Medicine, 1999
... phospho-p44/42 MAP kinase [T202/Y204] against ERK1 and 2 and phospho-Akt [Ser473] against PKB/Akt (New England Biolabs); anti-ERK2 (C-14) and anti-Akt1/2 (H-136; Santa Cruz Biotechnology); the mouse monoclonal IgG1 ...
A conserved docking motif in MAP kinases common to substrates, activators and regulators.
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Koch Karl-Wilhelm, In PLoS ONE, 1999
... Cobb) or ERK2 mutants C38A, C214A and C214E (Genscript, Piscataway, NJ, USA), with ...
Phosphorylation of actopaxin regulates cell spreading and migration
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Turner Christopher E. et al., In The Journal of Cell Biology, 1999
... Active Erk2 was obtained from New England Biolabs, Inc ...
Impairment of erbb1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma du145 cells
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Saad Fred et al., In Frontiers in Oncology, 1999
... Antibodies recognizing phospho-AKT (S473; cat# 9271), phospho-PDK1 (S241; 3438) and phospho-ERK (T202/Y204; cat# 9106L) were obtained from Cell Signaling (Danvers, MA, USA) ...
Nerve growth factor- and epidermal growth factor-regulated gene transcription in PC12 pheochromocytoma and INS-1 insulinoma cells.
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Defossez Pierre-Antoine, In PLoS ONE, 1999
... Polyclonal antibodies to EGR1 and ERK 1/2 were obtained from Santa Cruz Biotechnology (Santa Cruz, CA) ...
An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin–polymerizing machine
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Di Fiore Pier Paolo et al., In The Journal of Cell Biology, 1998
... ) sera; rabbit polyclonals anti–Sos-1, anti-Grb2, and anti–ERK-1, (Santa Cruz Biotechnology, Inc.); monoclonals anti-myc and ...
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells
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Birchmeier Walter et al., In The Journal of Cell Biology, 1998
... Flag tag from Sigma-Aldrich, antibodies to active Akt pS473 from Cell Signaling, and anti–Akt-PKBα and pan–Erk antibodies from BD Biosciences.
The EGF receptor as central transducer of heterologous signalling systems.
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Hong Wanjin, In PLoS ONE, 1998
... antibodies, EGFR and Src antibodies, anti-phospho-p44/42 ERK (Thr202/Tyr204) (197G2) mouse monoclonal antibody (mAb) and anti-p44/42 ERK (137F5) rabbit mAb were all purchased from Cell Signaling Technology (Boston, MA) ...
A novel role for FGF and extracellular signal–regulated kinase in gap junction–mediated intercellular communication in the lens
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Musil Linda S. et al., In The Journal of Cell Biology, 1998
... forms of ERK) and the antiphospho-p44/42 MAP kinase E10 monoclonal mouse antibody (specific for activated ERK) were purchased from New England Biolabs, Inc ...
Differential αv integrin–mediated Ras-ERK signaling during two pathways of angiogenesis
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Cheresh David A. et al., In The Journal of Cell Biology, 1997
... A phosphospecific antibody raised against ERK phosphorylated at threonine 202/tyrosine204 (Cell Signaling Technologies) was used for ...
Differential regulation of Pyk2 and focal adhesion kinase (FAK)
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Schlaepfer David D. et al., In The Journal of Cell Biology, 1997
... Polyclonal antibodies to JNK1/2 (sc-572) and to ERK2 (c-14) were purchased from Santa Cruz Biotechnology, Inc., and antibodies to ...
Avian neural crest-derived neurogenic precursors undergo apoptosis on the lateral migration pathway
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Klemke Richard L. et al., In The Journal of Cell Biology, 1997
... Bcl-2, MEK, ERK, and CAS specific antibodies were from Santa Cruz Biotechnology, and anti-Crk was from ...
STAT3 mediates the survival signal in oncogenic ras-transfected intestinal epithelial cells
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Asano T et al., In British Journal of Cancer, 1997
... Signaling Technology Inc., Beverly, MA, USA), STAT3 (Cell Signaling Technology Inc), phospho-extracellular-activated protein kinase (ERK) (p-ERK, Cell Signaling Technology Inc.), ERK (Cell ...
Active MAP kinase in mitosislocalization at kinetochores and association with the motor protein CENP-E
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Shapiro Paul et al., In The Journal of Cell Biology, 1997
... Lamin B (M-20), pY ERK (E-4), ERK1 (C-16), ERK2 (C-14), and MKK1 (C-18) antibodies were purchased from Santa Cruz Biotechnology, Inc ...
Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
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Giancotti Filippo G. et al., In The Journal of Cell Biology, 1997
... (C-19), anti-Erk2 (C-14), anti-PAK (N-20), and anti-Merlin (A-19, C-18; Santa Cruz Biotechnology, Inc.); anti–β-actin (Sigma-Aldrich); anti–phospho-ERK (Cell Signaling); anti-Ras and anti–VE-cadherin (BD ...
Compartmentalization of integrin α6β4 signaling in lipid rafts
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Giancotti Filippo G. et al., In The Journal of Cell Biology, 1997
... (anti-phospho-ERK), Santa Cruz Biotechnology, Inc ...
Receptor tyrosine kinase c-ros knockout mice as a model for the study of epididymal regulation of sperm function
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Böhmer Frank D. et al., In The Journal of Cell Biology, 1997
... recognizing activated, phosphorylated extracellular signal regulated kinases (Erks, “phospho-p44/42 MAPK antibody”) and against Erk kinase (“pan-Erk antibody”) were from Cell Signaling Technology, Inc., and Transduction ...
Negative Regulation of Immunoglobulin E–dependent Allergic Responses by Lyn Kinase
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Rivera Juan et al., In The Journal of Experimental Medicine, 1996
... ), Hck (M28), Src (N16), Csk-binding protein (Cbp), Csk, ERK2, and p38MAPK were from Santa Cruz Biotechnology, Inc ...
Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells
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Santoni Angela et al., In The Journal of Experimental Medicine, 1996
... The affinity-purified antiserum against Erk2 was obtained from Santa Cruz Biotechnology, Inc. ...
Analyzing chemotaxis using the Dunn direct-viewing chamber
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Ridley Anne J. et al., In The Journal of Cell Biology, 1996
... 05-180; Millipore), α-tubulin DM1A clone (T6199; Sigma-Aldrich), and rabbit polyclonal extracellular signal–regulated kinase (ERK), K-23 (sc-94; Santa Cruz Biotechnology).
Signal characteristics of G protein-transactivated EGF receptor
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Hexum Terry D. et al., In Purinergic Signalling, 1996
... ) and rabbit-anti-ERK 1/2 (Cell Signaling Technology, Boston, MA, USA) ...
Raf-1 activation disrupts its binding to keratins during cell stress
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Omary M. Bishr et al., In The Journal of Cell Biology, 1996
... Additional Abs used were directed to: 14-3-3ζ, Raf-1, Raf pS259, Raf pS621, and Erk (Santa Cruz Biotechnology, Inc.); mAb 4.62, which ...
Detection of ERK activation by a novel monoclonal antibody
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Ahn Natalie G. et al., In The Journal of Cell Biology, 1996
... Immunoblots were also probed using a rabbit polyclonal antibody recognizing the COOH terminus of ERK2 (C-14; Santa Cruz Biotechnology ...
Association of CSK-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cells
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Klemke Richard L. et al., In The Journal of Cell Biology, 1996
... Rabbit antibodies to the ErbB1, -2, -3, -4, p130CAS, and ERK2 were from Santa Cruz Biotechnology, Inc ...
Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E–cdk2, and phosphorylation of the retinoblastoma protein
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Yamada Kenneth M. et al., In The Journal of Cell Biology, 1995
... monoclonal antibody 9E10 against the Myc epitope (BAbCo) and a monoclonal antibody against the phosphorylated Thr202/Tyr204 ERK activation epitope (New England Biolabs, Inc.) ...
Differential damage to auditory neurons and hair cells by ototoxins and neuroprotection by specific neurotrophins in rat cochlear organotypic cultures
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Hong Seung-Heon et al., In Environmental Health Perspectives, 1995
... Caspase-3, caspase-9, cyt c, phosphorylated-ERK (p-ERK), and total-ERK antibodies were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
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Tanaka Sakae et al., In The Journal of Cell Biology, 1995
... MEK inhibitor PD98059, anti–phospho-ERK and anti–IκB-α antibodies were purchased from New England Biolabs, Inc., anti–v-src antibody (clone ...
Overexpression of Rad inhibits glucose uptake in cultured muscle and fat cells.
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Orsulic Sandra, In PLoS ONE, 1995
... pACC (Ser79), ACC were purchased from Cell Signaling Technology (Beverly, MA), LKB1, Tubulin, Akt and Erk were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2
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Sundler Roger et al., In Journal of Inflammation (London, England), 1995
... Antibodies against p-JNK, PLC-γ2, ERK-2 and phosphotyrosine as well as HRP conjugated secondary antibodies, were from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells
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Lucio-Cazana Francisco Javier et al., In Journal of Neuroinflammation, 1995
... Primary antibodies against COX-1, COX-2, RAR-β and total ERK2 were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Localizing the NADP+ binding site on the MurB enzyme by NMR.
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Blagosklonny Mikhail V., In PLoS ONE, 1995
... Anti-phospho and -total ERK antibodies were from Cell Signaling Technology (Beverly, MA) ...
Continuous HGF supply from HGF-expressing fibroblasts transplanted into spleen prevents CCl4-induced acute liver injury in rats.
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Xu Aimin, In PLoS ONE, 1995
... Anti-Erk1/Erk2 rabbit mAb, anti-phospho-Erk1/Erk2 (Thr202/Tyr204) rabbit mAb were purchased from Cell Signaling Technology (Danvers, MA, USA) ...
Spatiotemporal Dynamics of CREB Phosphorylation: Transient versus Sustained Phosphorylation in the Developing Striatum.
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Bartolomucci Alessandro, In PLoS ONE, 1995
... anti-p-Akt1 (Ser47, sc-7985-R), anti-p-JNK (Thr183/Tyr185, sc-12882-R), anti-JNK (sc-572), anti-Actin (sc-10731), goat polyclonal anti-Akt (sc-7126), and anti-ERK (sc-94-G) antibodies were acquired from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Peptidase inhibitors improve recovery of substance P and calcitonin gene-related peptide release from rat spinal cord slices
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Hingtgen Cynthia M et al., In Molecular Pain, 1995
... titer, Santa Cruz Biotechnology; Integrin β-1: mouse monoclonal primary antibody, 1:300 titer, Santa Cruz Biotechnology; p-Erk 1/2: mouse monoclonal primary antibody, 1:500 titer, Cell Signaling Technologies; Erk 1/2: rabbit ...
Integrin-dependent activation of MAP kinasea link to shape-dependent cell proliferation
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Le T. Duong et al., In The Journal of Cell Biology, 1994
... (1249 and mAb E-12), PLC-γ2 (Q20 and mAb B-10), phospho–extracellular signal–regulated kinase (ERK) (E-4), and ERK2 (C-14) were from Santa Cruz Biotechnology, Inc ...
Growth factor–induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells
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Lander Arthur D. et al., In The Journal of Cell Biology, 1994
... (anti-ERK1/ERK2) was purchased from Promega or Cell Signaling Technology (similar results were ...
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
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Rivard Nathalie et al., In Molecular Cancer, 1994
... Antibodies recognizing phospho-ERK1/2 (Thr202/Tyr204) #9101 and total ERK were from Cell Signaling Technology (Danvers, MA) ...
The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression
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Vuori Kristiina et al., In The Journal of Cell Biology, 1994
... The anti–phospho-p44/42 MAPK antibody E10, which recognizes the active form of Erk, was from New England Biolabs, Inc., and the anti-Erk2 ...
Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation
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Cheresh David A. et al., In The Journal of Cell Biology, 1994
... A rabbit polyclonal antibody, C-14, raised against rat ERK2 was used for immunoprecipitation and Western blotting (Santa Cruz Biotechnology ...
Modulation of flagellar expression in Escherichia coli by acetyl phosphate and the osmoregulator OmpR.
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Masucci Maria G., In PLoS ONE, 1994
... Anti-total STAT3, anti-phosphorylated STAT3 (Ser705), anti-ERK and anti-phosphorylated ERK antibodies were purchased from Cell Signaling Technologies ...
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
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Tang Dean G., In PLoS ONE, 1994
... Rabbit anti-human phosphor-Erk1 (pT202/pY204)/Erk2 (pT185/pY187)Epitomics, Inc. ...
NMR View: A computer program for the visualization and analysis of NMR data.
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Cobine Paul, In PLoS ONE, 1993
... Anti-phospho and -total ERK antibodies were from Cell Signaling Technology ...
Osteopontin-stimulated vascular smooth muscle cell migration is mediated by β3 integrin
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Frazier William A. et al., In The Journal of Cell Biology, 1993
... Anti-ERK polyclonal antibody for Western blotting was from Santa Cruz Biotechnology, Inc ...
Isolation of new ribozymes from a large pool of random sequences
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Joyce Gerald, In PLoS Biology, 1992
... Santa Cruz, California, United States); and anti-(Tyr-phosphorylated) RET and anti-phospho-44/42 MAP kinase (also indicated as anti-[phospho]-ERK) monoclonal antibodies (E10) (both from Cell Signaling, Beverly, Massachusetts, United States) ...
Structure of the HMG box motif in the B-domain of HMG1
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Bianchi Marco E. et al., In The Journal of Cell Biology, 1992
... The monoclonal mouse antiphosphorylated MAP kinases (ERK 1 and 2) was from New England Biolabs, Inc ...
The mechanism of activation of protein kinase C: a biophysical perspective
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Suzuki Toshiyasu et al., In Acta Histochemica et Cytochemica, 1991
... Anti-phosphorylated-Raf (p-Raf), MEK, p-MEK, p-ERK and ERK antibodies were purchased from New England Biolabs, Inc ...
Identification and characterization of a novel cytoskeleton-associated pp60src substrate.
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Zamboni Dario S., In PLoS ONE, 1990
... Arlinet Kierbel (Montevideo Pasteur Institute, Montevideo, Uruguay), and mouse monoclonal anti-phosphoERK1/2 (Tyr204) and rabbit polyclonal anti-ERK antibodies were purchased from Santa Cruz Biotechnology (California, USA) ...
The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts
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Goff Stephen P. et al., In The Journal of Experimental Medicine, 1990
... Polyclonal antibodies against Vav, Raf-1, STAT3, STAT5a, STAT5b, and c-myc, and a monoclonal anti-Erk2 antibody were obtained from Santa Cruz Biotechnology ...
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
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Poulsen H S et al., In British Journal of Cancer, 1989
... phospho-EGFR (Tyr845, Tyr992, Tyr1045, Tyr1068), STAT3, phospho-STAT3 (Tyr705), AKT, phospho-AKT (Ser473), extracellular-regulated kinase (ERK)-1/2 and phospho-ERK-1/2 (Thr202/Tyr204) antibodies were from Cell Signaling Technology (Germany) ...
Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.
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Morla Alex O et al., In BMC Cell Biology, 1984
... Anti-phospho-p44/42 MAPK polyclonal antibody and anti-p44/42 ERK polyclonal antibody were purchased from New England Biolabs.
The cysteine rich region of Raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-Ras
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Hämmerling Ulrich et al., In The Journal of Experimental Medicine, 1982
... Antibodies to phosphorylated and nonphosphorylated extracellular signal–regulated kinase (ERK)1 and 2 were from New England Biolabs, Inc ...
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