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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

EPS8-like 3

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Eps8, HAD, Eps8L2, Eps8L1, CAN
Papers on Eps8L3
Exome sequencing identified a missense mutation of EPS8L3 in Marie Unna hereditary hypotrichosis.
Zhang et al., Hefei, China. In J Med Genet, 2012
RESULTS: We identified a missense mutation in EPS8L3 (NM_024526.3:
The arouser EPS8L3 gene is critical for normal memory in Drosophila.
Zars et al., Columbia, United States. In Plos One, 2010
Flies with a revertant aru allele had wild-type levels of memory performance, arguing that the aru gene, encoding an EPS8L3 product, has a role in Drosophila memory formation.
Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer.
Cross et al., Rockville, United States. In Cancer Res, 2009
The SNP rs11102001, which encodes a nonsynonymous amino acid change P356S in EPS8L3, is a potential candidate modifier of the effect of HCAs on prostate cancer risk.
Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3epsilon.
Saksela et al., Helsinki, Finland. In J Immunol, 2007
CD3epsilon bound well also to Eps8 and Eps8L3, and modestly to Eps8L2, but not detectably to other SH3 domains tested.
The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway.
Scita et al., Milano, Italy. In Mol Biol Cell, 2004
Here, we describe the identification and characterization of a family of eps8-related proteins, comprising three novel gene products, named eps8L1, eps8L2, and eps8L3.
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