Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3.
Philadelphia, United States. In Nat Neurosci, Nov 2015
Here we show using super-resolution imaging, biochemical approaches and in vivo models that the trans-synaptic organizing protein ephrin-B3 controls the synaptic localization and stability of PSD-95 and links these events to changes in neuronal activity via negative regulation of a newly identified mitogen-associated protein kinase (MAPK)-dependent phosphorylation site on ephrin-B3, Ser332.
Ephrin-B2 and ephrin-B3 as functional henipavirus receptors.
New York City, United States. In Semin Cell Dev Biol, 2012
Members of the ephrin cell-surface protein family interact with the Eph receptors, the largest family of receptor tyrosine kinases, mediating bi-directional signaling during tumorogenesis and various developmental events.
Henipavirus membrane fusion and viral entry.
Pullman, United States. In Curr Top Microbiol Immunol, 2011
The identification of ephrinB2 and ephrinB3 as henipavirus receptors has paved the way for recent advances in our understanding of henipavirus membrane fusion.
Epitope mapping of antibodies using bacterial surface display.
Stockholm, Sweden. In Nat Methods, 2008
We analyzed the binding sites of both monoclonal and polyclonal antibodies directed to three human protein targets: (i) the human epidermal growth factor receptor 2 (HER2), (ii) ephrin-B3 and (iii) the transcription factor SATB2.