EphA3 biology and cancer.
Australia. In Growth Factors, 2014
EphA3, originally isolated from leukemic and melanoma cells, is presently one of the most promising therapeutic targets, with multiple tumor-promoting roles in a variety of cancer types.
Mini-review: bmx kinase inhibitors for cancer therapy.
Birmingham, United States. In Recent Pat Anticancer Drug Discov, 2013
Evidence has been published that one member of this family; the Bmx kinase, may play a role in the pathogenesis of glioblastoma, prostate, breast and lung cancer.
Somatic mutations affect key pathways in lung adenocarcinoma.
Saint Louis, United States. In Nature, 2008
The frequently mutated genes include tyrosine kinases, among them the EGFR homologue ERBB4; multiple ephrin receptor genes, notably EPHA3; vascular endothelial growth factor receptor KDR; and NTRK genes.