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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ependymin related protein 1

The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: POLYMERASE, CAN, SET, HAD, beta Catenin
Papers on EPDR
Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension.
West et al., Nashville, United States. In Circulation, Feb 2015
Thirteen of 25 genes tested in whole blood were significantly different: EPDR1, DSG2, SCD5, P2RY5, MGAT5, RHOQ, UCHL1, ZNF652, RALGPS2, TPD52, MKNL1, RAPGEF2, and PIAS1.
Common variants of the EPDR1 gene and the risk of Dupuytren’s disease.
Serrano-Fernandez et al., Szczecin, Poland. In Handchir Mikrochir Plast Chir, 2013
In conclusion, results of this study suggest that EPDR1 gene can be added to a growing list of genes associated with Dupuytren's disease development.
Genetic characterization of vocal fold lesions: leukoplakia and carcinoma.
Dailey et al., Madison, United States. In Laryngoscope, 2012
RESULTS: Four genes (IGF-1, EPDR1, MMP-2, S100A4) were significantly upregulated in DYS over the ND group.
Comparative proteome analysis of 3T3-L1 adipocyte differentiation using iTRAQ-coupled 2D LC-MS/MS.
Tong et al., Changsha, China. In J Cell Biochem, 2011
In addition to previously reported differentially expressed molecules, more than 20 altered proteins previously unknown to be involved with adipogenic process were firstly revealed (e.g., HEXB, DPP7, PTTG1IP, PRDX5, EPDR1, SPNB2, STEAP3, TPP1, etc.).
Effects of combined siRNA-TR and -TERT on telomerase activity and growth of bladder transitional cell cancer BIU-87 cells.
Xie et al., Nanjing, China. In J Huazhong Univ Sci Technolog Med Sci, 2010
Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).
Influence of multiple genetic polymorphisms on genitourinary morbidity after carbon ion radiotherapy for prostate cancer.
Imai et al., Chiba, Japan. In Int J Radiat Oncol Biol Phys, 2008
RESULTS: When the SNP markers in the SART1, ID3, EPDR1, PAH, and XRCC6 genes in the training set were subjected to AUC-ROC curve analysis, the AUC-ROC curve reached a maximum of 0.86.
Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method.
Lobel et al., United States. In J Biol Chem, 2006
Shows that the mouse ortholog is a lysosomal protein.
Gene expression profiles characterize early graft response in living donor small bowel transplantation: a case report.
Cicalese et al., Worcester, United States. In Transplant Proc, 2006
The second profile identified 133 genes that were significantly decreased by threefold or greater immediately after transplant week 1, including UCC1, the human homolog of the Ependymin gene.
MERP1: a mammalian ependymin-related protein gene differentially expressed in hematopoietic cells.
Kirkland et al., Geelong, Australia. In Gene, 2002
We have obtained the full coding sequence of this gene which we designated human mammalian ependymin-related protein 1 (MERP1).
The novel ependymin related gene UCC1 is highly expressed in colorectal tumor cells.
Müller et al., Dortmund, Germany. In Cancer Lett, 2001
By this strategy the upregulation of a novel gene was detected designated as 'upregulated in colorectal cancer gene-1' (UCC1).
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