Evidence for synergistic activity of plant-derived essential oils against fungal pathogens of food.
Québec, Canada. In Food Microbiol, Feb 2016
The antifungal activities of eight essential oils (EOs) namely basil, cinnamon, eucalyptus, mandarin, oregano, peppermint, tea tree and thyme were evaluated for their ability to inhibit growth of Aspergillus niger, Aspergillus flavus, Aspergillus parasiticus and Penicillium chrysogenum.
Treg stability: to be or not to be.
Pittsburgh, United States. In Curr Opin Immunol, Feb 2016
Recent work suggests that the establishment and stability of Tregs is mediated by a number of mechanisms besides Foxp3 expression, such as epigenetic modifications, Foxo1/3a localization, expression of Eos and signaling via Neuropilin-1.
Monoclonal antibodies: the new magic bullets for allergy.
Jerusalem, Israel. In Br J Pharmacol, Jan 2016
They are characterized by tissue resident mast cell activation and consequent tissue infiltration and stimulation of several inflammatory cells and predominantly of eosinophils (Eos).
Fixation-resistant photoactivatable fluorescent proteins for CLEM.
United States. In Nat Methods, Mar 2015
Here we report engineered variants of the photoconvertible Eos fluorescent protein that fluoresce and photoconvert normally in heavily fixed (0.5-1% OsO4), plastic resin-embedded samples, enabling correlative super-resolution fluorescence imaging and high-quality electron microscopy.
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.
New York City, United States. In Nature, 2010
Here we show an association with genomic regions containing several genes controlling the activation and proliferation of regulatory T cells (T(reg) cells), cytotoxic T lymphocyte-associated antigen 4 (CTLA4), interleukin (IL)-2/IL-21, IL-2 receptor A (IL-2RA; CD25) and Eos (also known as Ikaros family zinc finger 4; IKZF4), as well as the human leukocyte antigen (HLA) region.