Netrin-1 prevents the development of cardiac hypertrophy and heart failure.
Lanzhou, China. In Mol Med Report, Feb 2016
Neonatal rat cardiomyocytes were stimulated with endothelin-1 (ET-1), and samples were collected to examine the expression levels of netrin‑1 by western blot analysis and the mRNA expression of A‑type natriuretic peptide by reverse transcription‑quantitative polymerase chain reaction.
Biomarkers in systemic sclerosis: Their potential to predict clinical courses.
Fukui, Japan. In J Dermatol, Jan 2016
Other potential serum/plasma biomarkers for fibrosis and vascular involvement of SSc are connective tissue growth factor, interleukin-6, CCL2, CXCL4, intercellular adhesion molecule (ICAM)-1, P-selectin, vascular endothelial growth factor, von Willebrand factor, endostatin, endoglin and endothelin-1.
Selexipag for the Treatment of Pulmonary Arterial Hypertension.
Le Kremlin-Bicêtre, France. In N Engl J Med, Jan 2016
Patients were eligible for enrollment if they were not receiving treatment for pulmonary arterial hypertension or if they were receiving a stable dose of an endothelin-receptor antagonist, a phosphodiesterase type 5 inhibitor, or both.
Acute Myocardial Response to Stretch: What We (don't) Know.
More papers using
Porto, Portugal. In Front Physiol, 2014
Calcium-dependent pathways, including angiotensin- and endothelin-related pathways; and cGMP-dependent pathways, comprising the effects of nitric oxide and cardiac natriuretic hormones, embody downstream signaling.