A 1.5Mb terminal deletion of 12p associated with autism spectrum disorder.
Curitiba, Brazil. In Gene, 2014
This 12p13.33 deletion is 1.5Mb in size and encompasses 13 genes (B4GALNT3, CCDC77, ERC1, FBXL14, IQSEC3, KDM5A, LINC00942, LOC574538, NINJ2, RAD52, SLC6A12, SLC6A13 and WNK1).
Active zones of mammalian neuromuscular junctions: formation, density, and aging.
Kansas City, United States. In Ann N Y Acad Sci, 2012
VDCCs interact extracellularly with the muscle-derived synapse organizer, laminin β2 and interact intracellularly with active zone-specific proteins, such as Bassoon, CAST/Erc2/ELKS2alpha, ELKS, Piccolo, and RIMs.
The presynaptic active zone.
Stanford, United States. In Neuron, 2012
Active zones are composed of an evolutionarily conserved protein complex containing as core constituents RIM, Munc13, RIM-BP, α-liprin, and ELKS proteins.
[Molecular mechanism at the presynaptic active zone].
Japan. In Brain Nerve, 2011
Presently, the full molecular composition of AZ is unclear, but it is known to contain several AZ-specific proteins, including cytomatrix of the active zone-associated protein (CAST)/ERC2, ELKS, RIM1, Munc13-1, Piccolo/Aczonin, and Bassoon.