Peroxynitrite mediates IL-8 gene expression and production in lipopolysaccharide-stimulated human whole blood
In PLoS ONE, 1997
... Antibodies and suppliers were as follows: rabbit polyclonal anti elastase (IgG, Calbiochem, San Diego, California, USA), chicken anti rabbit Alexa fluor 488 (IgG, Molecular probes, Eugene, Oregon, USA), goat polyclonal anti human IL-1β (IgG, Santa Cruz Biotechnology, Santa Cruz, California, USA), ...
SerpinB1 Promotes Pancreatic β Cell Proliferation.
Boston, United States. In Cell Metab, Feb 2016
Small-molecule compounds, that partially mimic serpinB1 effects of inhibiting elastase activity, enhanced proliferation of β cells, and mice lacking serpinB1 exhibit attenuated β cell compensation in response to insulin resistance.
Therapeutic Potential to Modify the Mucus Barrier in Inflammatory Bowel Disease.
Nanjing, China. In Nutrients, Dec 2015
We also review the involvement of the mucus barrier in the exacerbation of the disease and explore the therapeutic potential of modifying the mucus barrier with short-chain fatty acids, prebiotics, probiotics, fatty acid synthase, H₂S, neutrophil elastase inhibitor and phophatidyl choline.
Blood tests for acute pancreatitis.
Melbourne, Australia. In Aust Prescr, Aug 2015
New biomarkers including trypsinogen and elastase have no significant advantage over amylase or lipase.
Dietary modulation of the microbiome affects autoinflammatory disease.
Memphis, United States. In Nature, 2015
We further demonstrate that combined deletion of caspases 1 and 8 was required for protection against IL-1β-dependent inflammatory bone disease, whereas the deletion of either caspase alone or of elastase or neutrophil proteinase 3 failed to prevent inflammatory disease.