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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Chymotrypsin-like elastase family, member 1

Ela1, PC-TsF
Top mentioned proteins: elastase, POLYMERASE, CAN, HAD, p21
Papers on Ela1
Transcriptional programs regulated by both LEAFY and APETALA1 at the time of flower formation.
Wagner et al., Durham, United States. In Physiol Plant, Sep 2015
Finally, we show that the gibberellin catabolism enzyme ELA1, which was recently shown to be important for the timing of the switch to flower formation, is positively feedback-regulated by AP1.
A mechanically sensitive cell layer regulates the physical properties of the Arabidopsis seed coat.
Ingram et al., Lyon, France. In Nat Commun, 2014
We show that the adaxial epidermis of the outer integument thickens its cell wall in a mechanosensitive fashion, demonstrates microtubule dynamics consistent with mechanical stress perception and shows mechanosensitive expression of ELA1, a regulator of seed size and gibberellic acid (GA) metabolism.
The role of lymphotoxin signaling in the development of autoimmune pancreatitis and associated secondary extra-pancreatic pathologies.
Heikenwalder et al., Zürich, Switzerland. In Cytokine Growth Factor Rev, 2014
Expression of LT α and β on acinar cells in murine pancreata Tg(Ela1-Lta,b) mice led to chronic pancreatitis and sufficed to reproduce key features of human AIP including the development of autoimmunity and AIP associated secondary extra pancreatic pathologies.
Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress.
Svejstrup et al., London, United Kingdom. In Cell, 2013
Nuclear Def1 then binds RNAPII, utilizing a ubiquitin-binding domain to recruit the Elongin-Cullin E3 ligase complex via a ubiquitin-homology domain in the Ela1 protein.
Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis.
Heikenwalder et al., Zürich, Switzerland. In Gastroenterology, 2012
We created a mouse model of human AIP by overexpressing lymphotoxin (LT)α and β specifically in acinar cells (Ela1-LTab mice).
Changes in bowel microbiota induced by feeding weanlings resistant starch stimulate transcriptomic and physiological responses.
Tannock et al., Dunedin, New Zealand. In Appl Environ Microbiol, 2012
The altered microbiota was associated with changes in colonic short-chain fatty acid (SCFA) concentrations, colonic-tissue gene expression (Gsta2 and Ela1), and host physiology (serum metabolite profiles and colonic goblet cell numbers).
Two Arabidopsis cytochrome P450 monooxygenases, CYP714A1 and CYP714A2, function redundantly in plant development through gibberellin deactivation.
He et al., Shanghai, China. In Plant J, 2011
The Arabidopsis genome contains a tandemly duplicated gene pair ELA1 (CYP714A1) and ELA2 (CYP714A2) that encode EUI homologs.
FDG PET imaging of Ela1-myc mice reveals major biological differences between pancreatic acinar and ductal tumours.
Real et al., Barcelona, Spain. In Eur J Nucl Med Mol Imaging, 2009
PURPOSE: The aim was to evaluate FDG PET imaging in Ela1-myc mice, a pancreatic cancer model resulting in the development of tumours with either acinar or mixed acinar-ductal phenotype.
Genome-wide identification of allelic expression in hypertensive rats.
Doris et al., Houston, United States. In Circ Cardiovasc Genet, 2009
CONCLUSIONS: The result of these studies is the identification of several genes (Ptprj, Ela1, Dapk-2, and Gstt2) in which each of 4 SHR lines examined have fixed the same allele and in which each of 2 Wistar-Kyoto lines have a contrasting allele for which the inherited allele influences the level of gene expression.
Neurobehavioral basis of the impaired nurturing in mice lacking the immediate early gene FosB.
Kato et al., Saitama, Japan. In Brain Res, 2008
We found up-regulation of glial fibrillary acidic protein (GFAP), C4, and Ela1 mRNA in the MPOA of FosB (-/-) mice; all of these gene products were implicated in general neuropathological conditions.
Enzyme kinetics and characterization of mouse pancreatic elastase.
Starcher et al., Tyler, United States. In Connect Tissue Res, 2007
The enzymatic properties and kinetic profiles for mouse pancreatic elastase were similar to other known serine elastases.
Identification of glucocorticoid-regulated genes that control cell proliferation during murine respiratory development.
Cole et al., Australia. In J Physiol, 2007
Glucocorticoid receptor-null lungs included Chi3l3 (11-fold, P < 0.05), a macrophage inflammatory response gene and Ela1 (9.4-fold, P < 0.05), an extracellular matrix remodeling enzyme.
ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells.
Prakash et al., Galveston, United States. In Mol Cell Biol, 2007
Elongin A (Ela1) and cullin 3 (Cul3) are required for Pol II polyubiquitylation and degradation in yeast cells and an E3 comprised of elongin C (Elc1), Ela1, Cul3, and the RING finger protein Roc1 (Rbx1) mediates this process.
Inactivity of recombinant ELA2B provides a new example of evolutionary elastase silencing in humans.
Sahin-Tóth et al., Boston, United States. In Pancreatology, 2005
BACKGROUND: The archetypal mammalian elastase (ELA1) is not expressed in the human pancreas, because evolutionary mutations suppressed transcription of the ELA1 gene.
Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats.
Zeldin et al., United States. In Am J Physiol Renal Physiol, 2005
Conversely, elastase 1 (Ela1) was found to be the predominant gene downregulated in SHR at both time points.
Analysis of transcriptional regulatory regions in vivo.
Swift et al., Dallas, United States. In Int J Dev Biol, 1997
A summary of the in vivo regulatory properties of the pancreas-specific transcriptional enhancer of the rat elastase 1 gene (ELA1) and the role individual elements in this enhancer play in directing high level, cell-specific transcription illustrates the nature, revelations and limitations of transgenic analysis.
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