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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

EH-domain containing 4

EHD4, PAST-4
Top mentioned proteins: Eps15, EHD2, Transferrin, ACID, ARF6
Papers using EHD4 antibodies
The control of the false discovery rate in multiple testing under dependency.
Supplier
Kolb Martin, In PLoS ONE, 2000
... Anti-BiP, anti-EHD2 and anti-EHD4 antibodies were obtained from Stressgen Bioreagents (Ann Arbor, MI), Imgenex (San Diego, Ca), and ...
Papers on EHD4
A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males.
New
IMAGEN consortium et al., Heidelberg, Germany. In J Psychiatry Neurosci, Jan 2016
Furthermore, the most significant locus, originating from the EH-domain containing 4 (EHD4) gene (p < 0.001), was also significantly associated with altered ventral striatal activity in male adolescents performing an fMRI reward task (pempirical < 0.001).
SUMOylation of EHD3 Modulates Tubulation of the Endocytic Recycling Compartment.
Horowitz et al., Tel Aviv-Yafo, Israel. In Plos One, 2014
Of the four mammalian EHDs (EHD1-EHD4) EHD1 and EHD3 control traffic to the endocytic recycling compartment (ERC) and from the ERC to the plasma membrane, while EHD2 modulates internalization.
Role of the EHD2 unstructured loop in dimerization, protein binding and subcellular localization.
Caplan et al., Omaha, United States. In Plos One, 2014
In contrast, despite EHD2 having nearly 70% amino acid identity with its paralogs, EHD1, EHD3 and EHD4, the latter proteins contain a single KPF or RPF motif, but no NPF motif.
Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.
Caplan et al., Omaha, United States. In J Biol Chem, 2013
EHD4 serves a role similar to that of EHD1 in TRE vesiculation, whereas EHD2, despite being capable of vesiculating TREs in the semipermeabilized cells, fails to do so in vivo.
Comparative proteomic analysis of HIV-1 particles reveals a role for Ezrin and EHD4 in the Nef-dependent increase of virus infectivity.
Basmaciogullari et al., Paris, France. In J Virol, 2013
We observe that glucosidase II is enriched in WT virions, whereas Ezrin, ALG-2, CD81, and EHD4 are enriched in nef-deleted virions.
Ehd4 encodes a novel and Oryza-genus-specific regulator of photoperiodic flowering in rice.
Wan et al., Nanjing, China. In Plos Genet, 2012
Here, we report isolation and characterization of a positive regulator of Ehd1, Early heading date 4 (Ehd4).
Role of phosphatidylinositol 4,5-bisphosphate in regulating EHD2 plasma membrane localization.
Naslavsky et al., Omaha, United States. In Plos One, 2012
The four mammalian C-terminal Eps15 homology domain-containing proteins (EHD1-EHD4) play pivotal roles in endocytic membrane trafficking.
EHD2 shuttles to the nucleus and represses transcription.
Horowitz et al., Tel Aviv-Yafo, Israel. In Biochem J, 2012
There are four EHD proteins in mammalian cells, EHD1-EHD4, each with diverse roles in the recycling pathway of endocytosis.
Transcriptional response of the bovine endometrium and embryo to endometrial polymorphonuclear neutrophil infiltration as an indicator of subclinical inflammation of the uterine environment.
Heuwieser et al., Bonn, Germany. In Reprod Fertil Dev, 2011
Of these, GZMK, TCEAL4, MYL7, ADD3 and THEM50B were upregulated, whereas NUDCD2, MYO1E, BZW1, EHD4 and GZMB were downregulated.
Eps homology domain endosomal transport proteins differentially localize to the neuromuscular junction.
Hoffman et al., Washington, D.C., United States. In Skelet Muscle, 2011
In this study, we investigated the localization of EHD1 and its paralogs EHD2, EHD3, and EHD4 in mouse skeletal muscle, and assessed the morphological changes in EHD1-/- NMJs.
Endocytosis and endosomes at the crossroads of regulating trafficking of axon outgrowth-modifying receptors.
Review
Yap et al., Charlottesville, United States. In Traffic, 2011
Growth-promoting neurotrophins and growth-inhibiting Nogo-A can use EHD4/Pincher-dependent endocytosis at the growth cone for their respective retrograde signaling.
Trk retrograde signaling requires persistent, Pincher-directed endosomes.
GeneRIF
Halegoua et al., Stony Brook, United States. In Proc Natl Acad Sci U S A, 2011
Retrograde signaling through Pincher-generated Trk-multivesicular bodies is distinctively refractory to signal termination by lysosomal processing
Renal thrombotic microangiopathy in mice with combined deletion of endocytic recycling regulators EHD3 and EHD4.
GeneRIF
Band et al., Omaha, United States. In Plos One, 2010
EHD-mediated endocytic traffic of key surface receptors such as VEGFR2 is essential for physiological control of glomerular function.
EH domain proteins regulate cardiac membrane protein targeting.
GeneRIF
Mohler et al., Iowa City, United States. In Circ Res, 2010
A new class of cardiac trafficking proteins(EHD1, EHD2, EHD3, EHD4) regulates cardiac membrane protein targeting.
Alterations of EHD1/EHD4 protein levels interfere with L1/NgCAM endocytosis in neurons and disrupt axonal targeting.
Winckler et al., Charlottesville, United States. In J Neurosci, 2010
The Eps15 homology domain (EHD) family proteins (EHD1-EHD4) play important roles in endosomal recycling and possibly in endocytosis.
Ehd4 is required to attain normal prepubertal testis size but dispensable for fertility in male mice.
GeneRIF
Band et al., Omaha, United States. In Genesis, 2010
Results suggest a role for EHD4 in the proper development of postmitotic and postmeiotic germ cells.
EHD4 and CDH23 are interacting partners in cochlear hair cells.
GeneRIF
Zheng et al., Evanston, United States. In J Biol Chem, 2009
EHD4 is a novel CDH23-interacting protein that could regulate CDH23 trafficking/localization in a calcium-sensitive manner.
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