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Epidermal growth factor receptor

EGFR
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010] (from NCBI)
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AbD serotecEGFREGFR
Papers using EGFR antibodies
Studying lipids involved in the endosomal pathway.
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Johannes Ludger, In PLoS ONE, 2011
... South San Francisco, CA); EEA1 (Transduction Laboratories); LAMP1 (CD107a; BD Biosciences); EGFR (BD Biosciences); α-tubulin (Sigma- Aldrich) ...
Total internal reflection STED microscopy
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Bewersdorf Joerg et al., In Biomedical Optics Express, 2010
... A linker encoding the signal sequence of EGFR was inserted into 5′ MCS of pSNAPf vector (New England Biolabs) using the unique NheI ...
Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer
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Croce Carlo M. et al., In Nature medicine, 2010
... Targeting of both the c-Met and EGFR pathways results in additive inhibition of lung tumorigenesis in transgenic mice ...
Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains.
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Caplan Steve H., In PLoS ONE, 2009
... Louis, MO), and mouse anti-EGFR was from Cell signaling technology (Danvers, MA) ...
Expression profiling of ETS and MMP factors in VEGF-activated endothelial cells: role of MMP-10 in VEGF-induced angiogenesis.
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Gaetano Carlo, In PLoS ONE, 2009
... Materials: The antibodies of VEGF, PEDF, TNF-α, epidermal growth factor receptor (EGFR) were purchased from Abcam, Cambridge, MA, USA ...
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Papers on EGFR
Serine protease inhibitor Kazal type 1 and epidermal growth factor receptor are expressed in pancreatic tubular adenocarcinoma, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia.
New
Baba et al., Kumamoto, Japan. In J Hepatobiliary Pancreat Sci, 12 Apr 2013
BACKGROUND: Serine protease inhibitor Kazal type 1 (SPINK1) is expressed in normal human pancreatic acinar cells and in a variety of tumors, and binds to the epidermal growth factor receptor (EGFR), mediating cell proliferation through the mitogen-activated protein kinase cascade in pancreatic cancer cell lines.
Role of epidermal growth factor receptor inhibitors in epidermal growth factor receptor wild-type non-small-cell lung cancer.
New
Impact
Goss et al., Ottawa, Canada. In J Clin Oncol, 10 Apr 2013
Worldwide, the majority of patients with advanced non-small-cell lung cancer (NSCLC) do not have activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR).
Treating Patients With EGFR-Sensitizing Mutations: First Line or Second Line--Is There a Difference?
New
Impact
Lam et al., Hong Kong, Hong Kong. In J Clin Oncol, 10 Apr 2013
First-line epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) is a standard treatment for patients with activating EGFR mutations.
Pemetrexed and carboplatin followed by pemetrexed maintenance therapy in chemo-naïve patients with advanced nonsquamous non-small-cell lung cancer.
New
Tamura et al., Ōsaka, Japan. In Invest New Drugs, 10 Apr 2013
Pre-planned subgroup analysis results based on the presence of epidermal growth factor receptor (EGFR) mutations are also presented.
Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease.
New
Impact
Pao et al., Nashville, United States. In J Clin Oncol, 10 Apr 2013
METHODS This article reviews the clinical implications of EGFR mutations in lung cancer with a focus on epidermal growth factor receptor tyrosine kinase inhibitor resistance.
The KRAS mutation detection within the initial management of patients with metastatic colorectal cancer: A status report in France in 2011.
New
Ducreux et al., Saint-Cloud, France. In Eur J Cancer, 06 Apr 2013
BACKGROUND: The detection of KRAS mutations is mandatory to initiate an anti-epidermal growth factor receptor (EGFR) antibody in the treatment of metastatic colorectal carcinoma (mCRC).
A targeted adenovirus vector displaying a human fibronectin type III domain-based monobody in a fiber protein.
New
Mizuguchi et al., Ōsaka, Japan. In Biomaterials, 05 Apr 2013
To overcome this problem, we developed a fiber-mutant Ad vector displaying a monobody specific for epidermal growth factor receptor (EGFR) or vascular endothelial growth factor receptor 2 (VEGFR2) in the C-terminus of the knobless fiber protein derived from T4 phage fibritin.
Phase III Randomized, Placebo-Controlled Trial of Docetaxel With or Without Gefitinib in Recurrent or Metastatic Head and Neck Cancer: An Eastern Cooperative Oncology Group Trial.
New
Impact
Forastiere et al., San Antonio, United States. In J Clin Oncol, 04 Apr 2013
PURPOSEWe hypothesized that the addition of gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, to docetaxel would enhance therapeutic efficacy in squamous cell carcinoma of the head and neck (SCCHN).
Cisplatin and Radiotherapy With or Without Erlotinib in Locally Advanced Squamous Cell Carcinoma of the Head and Neck: A Randomized Phase II Trial.
New
Impact
Hayes et al., Covington, United States. In J Clin Oncol, 04 Apr 2013
Cetuximab-radiotherapy is superior to radiotherapy alone in this population, validating epidermal growth factor receptor (EGFR) as a target.
[Setting up a department of molecular pathology in oncology in a pathology laboratory (LPCE, CHU de Nice)].
New
Hofman et al., Nice, France. In Ann Pathol, 28 Feb 2013
KRAS gene mutations in metastatic colon adenocarcinoma or EGFR gene mutations in lung adenocarcinomas), may lead to administration of targeted therapies under the Marketing Authorization Application (MAA), others are associated with therapeutic clinical trials.
Redox regulation of epidermal growth factor receptor signaling through cysteine oxidation.
Review
New
Carroll et al., Ann Arbor, United States. In Biochemistry, Jan 2013
Epidermal growth factor receptor (EGFR) exemplifies the family of receptor tyrosine kinases that mediate numerous cellular processes, including growth, proliferation, and differentiation.
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
New
Impact
GeneRIF
Marais et al., Nutley, United States. In N Engl J Med, Feb 2012
Mutations in RAS, particularly HRAS, are frequent in cutaneous squamous-cell carcinomas and keratoacanthomas that develop in patients treated with vemurafenib.
Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity.
GeneRIF
Carroll et al., Ann Arbor, United States. In Nat Chem Biol, 2012
Oxidation of the EGFR active site modulates kinase activity
Suppression of EGFR autophosphorylation by FKBP12.
GeneRIF
Schiene-Fischer et al., Halle, Germany. In Biochemistry, 2012
Results suggest that FKBP12 forms an endogenous inhibitor of EGFR phosphorylation directly involved in control of cellular EGFR activity (as in carcinoma).
Guanylate binding protein 1 is a novel effector of EGFR-driven invasion in glioblastoma.
GeneRIF
Furnari et al., San Diego, United States. In J Exp Med, 2012
establish GBP1 as a previously unknown link between EGFR activity and MMP1 expression and nominate it as a novel potential therapeutic target for inhibiting GBM invasion.
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.
Impact
GeneRIF
Iafrate et al., Boston, United States. In Cancer Cell, 2012
multiple receptor tyrosine kinases are amplified in a subset of glioblastoma subclones, epidermal growth factor receptor, MET and platelet-derived growth factor receptor alpha
Role of fluorescence in situ hybridization in lung cancer cytology.
Review
Bubendorf et al., Basel, Switzerland. In Acta Cytol, 2011
EGFR mutation analysis is the method of choice for selecting patients for therapy with EGFR tyrosine kinase inhibitors (TKIs), whereas the EGFR gene copy number has not been confirmed as a reliable predictive marker.
Molecular characterization by immunocytochemistry of lung adenocarcinoma on cytology specimens.
Review
Hasanovic et al., New York City, United States. In Acta Cytol, 2011
The discovery of targetable driver mutations in pulmonary adenocarcinoma has revolutionized the field of thoracic oncology by the introduction of oral small molecule tyrosine kinase inhibitors that target specific EGFR mutations and EML-4/ALK rearrangement.
Current status of radiosensitizing agents for the management of rectal cancer.
Review
Illum, Dallas, United States. In Crit Rev Oncog, 2011
Increased topoisomerase I expression and increased EGFR gene copy number as possible predictors of response to irinotecan- and cetuximab-based chemoradiation, respectively, deserve further studies.
EGFR gene mutation study in cytology specimens.
Review
Wong et al., Hong Kong, Hong Kong. In Acta Cytol, 2011
Activating mutations of the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancer predicts a significantly higher clinical response rate to tyrosine kinase inhibitors targeting EGFR, and it is currently recommended that patients under consideration for EGFR TKI as first-line therapy be tested for such mutations to determine the appropriateness of treatment.
More papers using EGFR antibodies
Emerging roles of Wnts in the adult nervous system.
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Katoh Masaru, In PLoS ONE, 2009
... Anti phospho-ERK1/2, antiphospho-EGFR (Tyr1068 and Tyr1086), antiphospho-Akt (S473) and total EGFR antibodies were from Cell Signaling Technology Inc (Danvers, MA, ...
Treatment of eccrine porocarcinoma with metastasis to the parotid gland using intensity-modulated radiation therapy: a case report
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Hoque Mohammad O., In PLoS ONE, 2009
... CA), ER (SP1, prediluted, Ventana Medical Systems, Tucson, AZ), PR (1E2, prediluted, Ventana Medical Systems), EGFR (3C6, prediluted, Ventana Medical Systems), and HER2 (4B5, prediluted, ...
Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH
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Domagala Wenancjusz et al., In Virchows Archiv, 2008
... EGFR staining was performed using the EGFR pharmDx kit (Dako) with incubation with proteinase ...
Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non-small-cell lung cancer
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Smrdel Uros et al., In Journal of Biomedicine and Biotechnology, 2008
... To detect EGFR gene-activating mutations, we used TheraScreen EGFR29 Mutation Kit (DxS Diagnostics, Qiagen, Manchester, UK) ...
Response to neoadjuvant therapy with cisplatin in BRCA1-positive breast cancer patients
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Richardson Andrea L et al., In Breast Cancer Research : BCR, 2008
... USA), CK18 (DC10 antibody, Dako) and CK19 (RCK108 antibody, Dako) as well as for EGFR (EGFR pharmDX kit, Dako) and p53 (DO-7 antibody, ...
Effect of gefitinib on N-nitrosamine-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mice.
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Sun Shi-Yong, In PLoS ONE, 2008
Santa Cruz), anti-β-Tubulin and -β-Actin (Sigma-Aldrich); and anti-phospho-EGFR (Y1086, Abcam), and anti-EGFR, -ERK, -Akt ...
Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy.
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Carvalho Luzia Helena, In PLoS ONE, 2008
... Antibodies to GAPDH, EGFR, MCP-1, and RANTES were purchased from Santa Cruz Biotechnology, Inc ...
Higher constitutive IL15R alpha expression and lower IL-15 response threshold in coeliac disease patients.
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Holowka David, In PLoS ONE, 2007
... Cruz Biotechnology, Santa Cruz, CA, USA) and mouse anti-alpha tubulin (Sigma-Aldrich, Milan, Italy) and rabbit anti-EGFR (Cell Signaling Celbio, Milan, Italy) antibodies ...
Lysine acetylation: codified crosstalk with other posttranslational modifications
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Sorkin Alexander et al., In The Journal of Cell Biology, 2007
... monoclonal antibody to ubiquitin (P4D1), rabbit polyclonal antibodies to Grb2, Cbl (C-15), Shc (H-108), and EGFR (1005) were purchased from Santa Cruz Biotechnology, Inc ...
HGF-independent Potentiation of EGFR Action by c-Met
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Siegfried Jill M. et al., In Oncogene, 2007
... Mouse anti-c-Met, rabbit anti-EGFR, rabbit anti-Y1234/35-Met and anti-rabbit and anti-mouse-HRP linked secondary antibodies were obtained from Cell Signaling (Beverly, MA) ...
Close-to-native ultrastructural preservation by high pressure freezing
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Bergmann Andreas, In PLoS ONE, 2007
... The following EGFR RNAi transgenic lines were used: ...
Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling
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Waugh M G et al., In Cell Death & Disease, 2006
... Anti-EGFR was from Cell Signaling Technologies (Hertfordshire, UK) and ...
Decreased expression of antioxidant enzymes and increased expression of chemokines in COPD lung
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van Oosterhout Antoon J et al., In Respiratory Research, 2006
... EGFR and phospho-EGFR detected by western blotting using anti-phospho-EGFR (1173 tyrosine residue) and anti-EGFR (Santa Cruz Biotechnology, Santa Cruz, CA) ...
CXCL10 promotes invasion-related properties in human colorectal carcinoma cells
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Wang J M et al., In British Journal of Cancer, 2006
... against phosphorylated Akt, Akt, phosphorylated p38, p38, phosphorylated Erk, Erk, phosphorylated EGFR (tyrosine 992) and EGFR were from Cell Signaling Technology (Beverly, MA, USA) ...
Potential use of an anticancer drug gefinitib, an EGFR inhibitor, on allergic airway inflammation.
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Munderloh Ulrike Gertrud, In PLoS ONE, 2006
... antibody against phospho-IκBα, IκBα, phospho-IKKα/β, IKKα, IKKβ, phospho-p38, p38, phospho-MKK3/6, MKK3, phospho-Akt, Akt, phospho-EGFR and EGFR were purchased from Cell Signaling (MA, USA) ...
Neuroprotection and stroke: time for a compromise
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Docagne Fabian et al., In The Journal of Experimental Medicine, 2006
... Rabbit anti–mouse pErk1/2 and pAkt and anti–mouse phosphorylated EGFR antibodies were obtained from Cell Signaling Technology ...
Detection of epidermal growth factor receptor and human epidermal growth factor receptor 2 activating mutations in lung adenocarcinoma by high-resolution melting amplicon analysis: correlation with gene copy number, protein expression, and hormone receptor expression
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Tan Puay-Hoon et al., In Breast Cancer Research : BCR, 2005
... Anti-EGFR monoclonal clone E30 (M7239, Dako, Glostrup, Denmark) was used ...
ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of Rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells.
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Blagosklonny Mikhail V., In PLoS ONE, 2005
... were all obtained from Cell Signaling Technology Inc (Danvers, MA) and anti-p-Tyr-EGFR1173 as well as anti-EGFR were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes.
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Cordes Nils, In PLoS ONE, 2005
... indicated suppliers: Cell Signaling Technologies: phospho-IGF-1R (tyrosine 1131/1135/1136), phospho-Akt (Ser 473), Akt, cleaved PARP, phospho-STAT3, EGFR and Akt1; Santa Cruz Biotechnology: IGF-1R, PTK6, Erk2, tubulin; ...
Effect of the anti-receptor ligand-blocking 225 monoclonal antibody on EGF receptor endocytosis and sorting.
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Lewin Alfred, In PLoS ONE, 2005
... To prepare the substrate for selection, human EGFR-Fc protein was immobilized to Protein G magnetic beads (New England Biolabs, Ipswich, MA) as follows: ...
Human tumor cell growth inhibition by nontoxic anthocyanidins, the pigments in fruits and vegetables
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Wulf Gerburg M et al., In Breast Cancer Research : BCR, 2004
... Phycoerythrin (PE)-conjugated mouse anti-EGFR antibody (EGFR.1,
Luteinising hormone-releasing hormone analogue reverses the cell adhesion profile of EGFR overexpressing DU-145 human prostate carcinoma subline
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Wells A et al., In British Journal of Cancer, 2004
... Primary antibodies to phospho-EGFR (Cell Signaling, Danvers, MA, USA), ...
Signal transduction for protease-activated receptor-2-triggered prostaglandin E2 formation in human lung epithelial cells
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Inagaki Chiyoko et al., In Respiratory Research, 2004
... human TGF-β1 was from Peprotech EC (Margravine Rode, London, UK); antibodies against E-cadherin, GAPDH and phospho-EGFR (specific for Tyr1173) were from Santa Cruz Biotechnology, Inc., (Santa Cruz, CA, ...
Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity
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Rodemann H Peter et al., In Molecular Cancer, 2004
... The EGFR-inhibitory antibody Erbitux was purchased from Merck KG aA, Germany and ...
Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts
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Chen Hong-Chen et al., In Journal of Biomedical Science, 2004
... Monoclonal anti-EGFR (ab30) was purchased from Abcam.
Label-Free Quantitation of Protein Modifications by Pseudo Selected Reaction Monitoring with Internal Reference Peptides
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Ham Amy-Joan L. et al., In Journal of Proteome Research, 2003
For Western blotting, primary antibodies forphosphotyrosine site 1172, phosphotyrosine site 998 and EGFR were purchased from Cell Signaling Technology (Danvers, MA) ...
Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor
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Press M F et al., In British Journal of Cancer, 2003
... A polyclonal rabbit antibody to the C-terminus epitope of EGFR was obtained from Santa Cruz Biotechnology, Santa Cruz, CA, USA ...
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
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Hynes Nancy E et al., In Breast cancer research : BCR, 2003
... used in this study: extracellular signal-regulated kinase 1/2 (ERK1/2), p-ERK1/2, total β-catenin, poly(ADP-ribose)polymerase (PARP), EGFR, p-EGFR (tyrosine [Tyr] 845), and p-Tyr-100 (Cell Signaling Technology, Inc., Danvers, MA, ...
Age-related changes in VEGF-dependency and angiopoietin-1 induced plasticity of adult blood vessels.
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Welm Alana L., In PLoS ONE, 2003
... The antibodies against VEGF (human-specific) and EGFR were purchased from Epitomics Inc ...
Expression of luminal and basal cytokeratins in human breast carcinoma
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Pogoda Katarzyna et al., In Journal of Neuro-Oncology, 2003
... Immunohistochemistry for cytokeratin 5/6 (Clone D5/16B4, DAKO, dilution scale 1:100), HER1 (EGFR pharm Dx, Clone 2-18C9, DAKO, RTU) and c-KIT (CD117, ...
Can correct protein models be identified?
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Jensen-Jarolim Erika et al., In Molecular Immunology, 2002
... removed with xylene from sections and immunohistochemistry was performed using the FDA-approved in vitro diagnostic EGFR pharm Dx™ (DAKO, Glostrup, Denmark) and HercepTest ...
Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
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Nurminsky Dmitry I., In PLoS ONE, 2002
... (Abcam, ab654), Glut3 (made in Devaskar's lab, UCLA), Glut1 (Abcam, ab15309), IGFR (Cell Signaling, 111A9), EGFR, (Santacruz, sc 03, 1005), Glucose-6-P dehydrogenase (Abcam, ab34436), Protein Kinase C-zeta ...
CD105 expression is a marker of high metastatic risk and poor outcome in breast carcinomas: correlations between immunohistochemical analysis and long-term follow-up in a series of 929 patients
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Saxena Sunita et al., In The Indian Journal of Medical Research, 2002
... the biomarkers- AR (Neomarkers; Fremont, CA, 1:50); ER (DAKO; Denmark, 1:50); PR (DAKO; Denmark, 1:50); EGFR (DAKO; Denmark, 1:50) and CD105 ...
Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth
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Meakin Susan O. et al., In The Journal of Cell Biology, 2001
... Other primary antibodies used were EGFR and GFP (Santa Cruz Biotechnology, Inc.), phospho-p44/42 MapK (New ...
Efficient expression system of human recombinant laminin-5.
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Chakravarti Shukti, In PLoS ONE, 2001
... integrin α6 (GoH3); mouse mAbs to integrin α3 (P1B5) and EGFR (528); rabbit pAbs to EGFR (1005), and integrin ß4 (H101) (Santa Cruz Biotechnology, Inc., Santa Cruz, CA); ...
The investigation of death from diseases caused by coal-burning type of arsenic poisoning
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Waalkes Michael P. et al., In Environmental Health Perspectives, 2001
... (sc-1616) and poly-clonal antibodies against cyclin D1 (sc-753), cdk4 (sc-601), and endothelial growth factor receptor (EGFR, sc-03) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Atomic model of the papillomavirus capsid.
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Imperiale Michael, In PLoS Pathogens, 2001
... siRNA cell transfection was performed using Lipofectamine 2000 reagent (Invitrogen), with EGFR siRNA (Cell Signaling) according to manufacturer's recommendations ...
Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells
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Friess Helmut et al., In Molecular Cancer, 2000
... Phospho-PDGFR-beta (tyr857) and p-EGFR (tyr1173) polyclonal antibodies were purchased from Santa Cruz Biotechnology, Inc ...
Gene Expression Omnibus
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Golub Todd R et al., In Genome Biology, 1998
... EGFR and mouse cKIT antibodies were purchased from Santa Cruz Biotechnology [ ...
Protein tyrosine phosphorylation influences adhesive junction assembly and follicular organization of cultured thyroid epithelial cells
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Turner T et al., In British Journal of Cancer, 1996
... -catenin, and p120 (Transduction Laboratories, California, USA), phosphorylated MARCKS (Cell Signaling, Massachusetts, USA), phosphorylated EGFR (Cell Signaling, Massachusetts, USA), and EGFR ...
The stress activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat
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Adler G et al., In British Journal of Cancer, 1995
... , and the EGFR were obtained from Santa Cruz Biotechnology (Santa Cruz, USA) ...
Prevention of radiolysis of monoclonal antibody during labeling
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van Dongen Guus A. M. S. et al., In European Journal of Nuclear Medicine and Molecular Imaging, 1995
... MAb cetuximab (Erbitux; 2.0 mg/ml) directed against the epidermal growth factor receptor (EGFR) was purchased from Merck (Darmstadt, Germany) [ ...
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
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Poulsen H S et al., In British Journal of Cancer, 1989
... The antiphospho-EGFR (Tyr1086) antibody was from Biosource (USA).Antibody to tubulin was from Santa Cruz Biotechnology Inc ...
Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose
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Johannes Ludger, In PLoS ONE, 1983
... The following primary antibodies were used: rabbit anti-EGFR antibody (Cell Signaling Technology); rabbit anti-COX IV ...
Nonparametric estimator from incomplete observations.
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Minna John D., In PLoS ONE, 1957
... Anti-EGFR (SC-03) antibody from Santa Cruz Biotechnology, Inc ...
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