miR-126 in human cancers: clinical roles and current perspectives.
Gold Coast, Australia. In Exp Mol Pathol, 2014
In addition, miR-126 can alter a multitude of cellular mechanisms in cancer pathogenesis via suppressing gene translation of numerous validated targets such as PI3K, KRAS, EGFL7, CRK, ADAM9, HOXA9, IRS-1, SOX-2, SLC7A5 and VEGF.
Angiogenic factors in bone local environment.
Australia. In Cytokine Growth Factor Rev, 2013
In addition, the expression of EGFL2, EGFL3, EGFL5, EGFL6, EGFL7, EGFL8 and EGFL9 has been recently identified in the bone local environment, giving important clues to their possible roles in angiogenesis.
miR-126 and miR-126*: new players in cancer.
Frankfurt am Main, Germany. In Scientificworldjournal, 2009
Studies indicate that two biologically active miRNAs miR-126 and its complement miR-126*, which are encoded by intron 7 of the egfl7 gene, have been described to mediate vascular functions.