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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Calmodulin-like 6

EF-hand protein
Top mentioned proteins: ACID, CAN, S-100, Centrin, Apo
Papers on EF-hand protein
Biochemical and biophysical characterization of a plant calmodulin: Role of the N- and C-lobes in calcium binding, conformational change, and target interaction.
New
Dominici et al., Verona, Italy. In Biochim Biophys Acta, Jan 2016
UNASSIGNED: In plants, transient elevation of intracellular Ca(2+) concentration in response to abiotic stress is responsible for glutamate decarboxylase (GAD) activation via association with calmodulin (CaM), an EF-hand protein consisting of two homologous domains (N and C).
Grancalcin (GCA) modulates Toll-like receptor 9 (TLR9)-mediated signaling through its direct interaction with TLR9.
New
Liu et al., Dallas, United States. In Eur J Immunol, Jan 2016
Here, we report that penta EF-hand protein Grancalcin (GCA) interacts and binds with TLR9 in a yeast two-hybrid system and an over-expression system.
The EF-Hand Ca2+ Binding Protein MICU Choreographs Mitochondrial Ca2+ Dynamics in Arabidopsis.
New
Schwarzländer et al., Bonn, Germany. In Plant Cell, Nov 2015
Here, we studied the function of At-MICU, an EF-hand protein of Arabidopsis thaliana with homology to constituents of the mitochondrial Ca(2+) uniporter machinery in mammals.
Annexins are instrumental for efficient plasma membrane repair in cancer cells.
Review
New
Nylandsted et al., Copenhagen, Denmark. In Semin Cell Dev Biol, Sep 2015
Plasma membrane repair in cancer cells depends on ANXA2 protein, which is recruited to the wound site and forms a complex with the Ca(2+)-binding EF-hand protein S100A11.
EF-hand protein Ca2+ buffers regulate Ca2+ influx and exocytosis in sensory hair cells.
New
Moser et al., Göttingen, Germany. In Proc Natl Acad Sci U S A, Apr 2015
EF-hand Ca(2+)-binding proteins are thought to shape the spatiotemporal properties of cellular Ca(2+) signaling and are prominently expressed in sensory hair cells in the ear.
Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2.
Maki et al., Nagoya, Japan. In Int J Mol Sci, 2014
ALG-2, a 22-kDa penta-EF-hand protein, is involved in cell death, signal transduction, membrane trafficking, etc., by interacting with various proteins in mammalian cells in a Ca2+-dependent manner.
GsCML27, a Gene Encoding a Calcium-Binding Ef-Hand Protein from Glycine soja, Plays Differential Roles in Plant Responses to Bicarbonate, Salt and Osmotic Stresses.
Zhu et al., Harbin, China. In Plos One, 2014
Together, these data present evidence that GsCML27 as a Ca2+-binding EF-hand protein plays a role in plant responses to bicarbonate, salt and osmotic stresses.
Mutation in the β-hairpin of the Bordetella pertussis adenylate cyclase toxin modulates N-lobe conformation in calmodulin.
Finley et al., Oxford, United States. In Biochem Biophys Res Commun, 2014
In the host cell, the adenylate cyclase domain of CyaA (CyaA-ACD) is activated upon association with calmodulin (CaM), an EF-hand protein comprised of N- and C-lobes (N-CaM and C-CaM, respectively) connected by a flexible tether.
Fish allergens at a glance: variable allergenicity of parvalbumins, the major fish allergens.
Review
Hentges et al., Luxembourg, Luxembourg. In Front Immunol, 2013
They are members of the calcium-binding EF-hand protein family characterized by a conserved protein structure.
Helminth Allergens, Parasite-Specific IgE, and Its Protective Role in Human Immunity.
Review
Dunne et al., Nottingham, United Kingdom. In Front Immunol, 2013
Nearly 20 molecular allergens have been isolated from this species, including tropomyosin (Ani s 3) and the EF-hand protein, Ani s troponin.
MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter.
Impact
Hajnóczky et al., Philadelphia, United States. In Cell Metab, 2013
Recent studies identified MCU as the uniporter's likely pore and MICU1, an EF-hand protein, as its critical regulator.
Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance.
Impact
Metzger et al., Minneapolis, United States. In Nat Med, 2013
Parvalbumin (Parv), the archetypal EF-hand protein, is a high-affinity Ca(2+) buffer in many biological systems.
Parvalbumin: calcium and magnesium buffering in the distal nephron.
Review
Devuyst et al., Brussels, Belgium. In Nephrol Dial Transplant, 2012
Parvalbumin (PV) is a classical member of the EF-hand protein superfamily that has been described as a Ca(2+) buffer and Ca(2+) transporter/shuttle protein and may also play an additional role in Mg(2+) handling.
Structure and function of ALG-2, a penta-EF-hand calcium-dependent adaptor protein.
Review
Shibata et al., Nagoya, Japan. In Sci China Life Sci, 2011
Like calmodulin, a well-known four-EF-hand protein, ALG-2 interacts with various proteins in a Ca(2+)-dependent fashion, but the binding motifs are completely different.
A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.
Impact
Gwack et al., Los Angeles, United States. In Nat Cell Biol, 2010
We sought to find modulators of Orai1 and STIM1 using affinity protein purification and identified a novel EF-hand protein, CRACR2A (also called CRAC regulator 2A, EFCAB4B or FLJ33805).
Cloning and characterization of human CAGLP gene encoding a novel EF-hand protein.
GeneRIF
Yu et al., Shanghai, China. In Dna Seq, 2004
a novel human gene, CAGLP (calglandulin-like protein) was predicted, and subsequently isolated from human skeleton muscle
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