Proteomic analysis of hepatocellular carcinoma HepG2 cells treated with platycodin D.
Aomen, Macao. In Chin J Nat Med, Sep 2015
Sixteen proteins were identified to be up-regulated in PD-treated HepG2 cells, including ATP5H, OXCT1, KRT9, CCDC40, ERP29, RCN1, ZNF175, HNRNPH1, HSP27, PA2G4, PHB, BANF1, TPM3, ECH1, LGALS1, and MYL6.
The ERBB3 receptor in cancer and cancer gene therapy.
Frederick, United States. In Cancer Gene Ther, 2008
Downstream it interacts prominently with the phosphoinositol 3-kinase/AKT survival/mitogenic pathway, but also with GRB, SHC, SRC, ABL, rasGAP, SYK and the transcription regulator EBP1.