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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Early B cell factor 1

EBF, EBF1, early B-cell factor, Olf-1
transcription factor that may regulate several olfactory-specific genes [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: Pax5, E12, CAN, OLF, FATE
Papers using EBF antibodies
Chemical cues mediating aphid location by natural enemies
Supplier
Gershenzon Jonathan et al., In BMC Ecology, 2007
... EBF emission from transgenic ...
Papers on EBF
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia.
New
Impact
Plass et al., Heidelberg, Germany. In Nat Genet, Feb 2016
Instead, we identified a potential pathogenic role for transcription factor dysregulation in CLL, where excess programming by EGR and NFAT with reduced EBF and AP-1 programming imbalances the normal B cell epigenetic program.
[Detection of copy number variations in pediatric ETV6/RUNX1-positive acute lymphoblastic leukemia with multiplex ligation-dependent probe amplification].
New
Zhu et al., Tianjin, China. In Zhongguo Dang Dai Er Ke Za Zhi, Jan 2016
The CNVs of EBF1, CDKN2A/2B, PAX5, ETV6, RB1, and BTG1 were detected in more than 10% of all the patients.
EBNA2 Drives Formation of New Chromosome Binding Sites and Target Genes for B-Cell Master Regulatory Transcription Factors RBP-jκ and EBF1.
New
Lieberman et al., Philadelphia, United States. In Plos Pathog, Jan 2016
We show here that EBV-encoded transcriptional regulator EBNA2 drives the cooperative and combinatorial genome-wide binding of two master regulators of B-cell fate, namely EBF1 and RBP-jκ.
Seedlings Transduce the Depth and Mechanical Pressure of Covering Soil Using COP1 and Ethylene to Regulate EBF1/EBF2 for Soil Emergence.
New
Zhong et al., Beijing, China. In Curr Biol, Jan 2016
We show that COP1 directly targets the F box proteins EBF1 and EBF2 for ubiquitination and degradation, thus stabilizing EIN3.
Tight Junction Ultrastructure Alterations in a Mouse Model of Enteral Nutrient Deprivation.
New
Teitelbaum et al., Ann Arbor, United States. In Dig Dis Sci, Jan 2016
BACKGROUND: Total parenteral nutrition (TPN), a necessary treatment for patients who cannot receive enteral nutrition, is associated with infectious complications due in part to a loss of intestinal epithelial barrier function (EBF).
Increased fat cell size: a major phenotype of subcutaneous white adipose tissue in non-obese individuals with type 2 diabetes.
New
Laurencikiene et al., Huddinge, Sweden. In Diabetologia, Dec 2015
Expression of genes encoding regulators of adipogenesis and adipose morphology (BMP4, CEBPα [also known as CEBPA], PPARγ [also known as PPARG] and EBF1) correlated negatively with fat cell size.
EIN2-Directed Translational Regulation of Ethylene Signaling in Arabidopsis.
New
Impact
Guo et al., Beijing, China. In Cell, Nov 2015
In this study, we report another mechanism of EIN2-mediated ethylene signaling, whereby EIN2 imposes the translational repression of EBF1 and EBF2 mRNA.
Can Brown Fat Win the Battle Against White Fat?
Review
New
Satyanarayana et al., Augusta, United States. In J Cell Physiol, Oct 2015
In this regard, recent finding that expression of early B cell factor-2 (Ebf2) reprograms the white pre-adipocytes into brown adipocytes is a significant break-through in developing BAT-mediated strategies to treat obesity.
Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia.
Review
New
Sigvardsson et al., Linköping, Sweden. In Blood, Aug 2015
Over the last few years, high-resolution analysis of genetic changes in leukemia has revealed that several key regulators of normal B-cell development, including IKZF1, TCF3, EBF1, and PAX5, are genetically altered in a large portion of the human B-lineage acute leukemias.
The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth.
New
Impact
Murre et al., San Diego, United States. In Nat Immunol, Jul 2015
Early B cell development is orchestrated by the combined activities of the transcriptional regulators E2A, EBF1, Foxo1 and Ikaros.
Regulation and evolution of cardiopharyngeal cell identity and behavior: insights from simple chordates.
Review
New
Christiaen et al., New York City, United States. In Curr Opin Genet Dev, Jun 2015
Activation of Ebf in pharyngeal muscle founder cells triggers both Myogenic Regulatory Factor-associated differentiation and Notch-mediated maintenance of an undifferentiated state in distinct precursors.
Identification of Putative Natriuretic Hormones Isolated from Human Urine.
Review
Kramer, Bonn, Germany. In Front Endocrinol (lausanne), 2014
Gel chromatography and reverse-phase (RP)-high performance liquid chromatography (HPLC) of lyophilized and reconstituted 24 h-urine from salt-loaded healthy humans led to two active fractions, a hydrophilic OLF-1 and a lipophilic OLF-2, whose mass (Ms)-spectroscopic data indicate a Mr of 391 (1, 2).
ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies.
Review
Morrone et al., Catanzaro, Italy. In Biomed Res Int, 2014
EBF1, a central component of this network, is essential for B-lymphoid specification and commitment as well as for the maintenance of the B-cell identity.
The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program.
Impact
Igarashi et al., Sendai, Japan. In Nat Immunol, 2014
Overexpression of Bach2 in pre-pro-B cells deficient in the transcription factor EBF1 and single-cell analysis of CLPs revealed that Bach2 and Bach1 repressed the expression of genes important for myeloid cells ('myeloid genes').
Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue.
Impact
Arner et al., Stockholm, Sweden. In Cell Metab, 2014
Herein, we identified EBF1 as an adipocyte-expressed transcription factor with decreased expression/activity in WAT hypertrophy.
Runx1-Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1.
GeneRIF
Taniuchi et al., Yokohama, Japan. In J Exp Med, 2012
Data indicate binding of Runx1-Cbfbeta complexes to the Ebf1 proximal promoter in early B cell development.
Lentiviral vector induced insertional haploinsufficiency of Ebf1 causes murine leukemia.
GeneRIF
Modlich et al., Hannover, Germany. In Mol Ther, 2012
Lentiviral vector induced insertional haploinsufficiency of Ebf1 causes murine leukemia
Essential role of EBF1 in the generation and function of distinct mature B cell types.
GeneRIF
Busslinger et al., Vienna, Austria. In J Exp Med, 2012
ectopic expression of EBF1 efficiently induced the development of B-1 cells at the expense of conventional B cells.
Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells.
GeneRIF
Grosschedl et al., Freiburg, Germany. In Genes Dev, 2012
found that Ebf1 is required for the proliferation, survival, and signaling of pro-B cells and peripheral B-cell subsets, including B1 cells and marginal zone B cells
Ebf1 deficiency causes increase of Müller cells in the retina and abnormal topographic projection at the optic chiasm.
GeneRIF
Xiang et al., United States. In Biochem Biophys Res Commun, 2011
These data together suggests that Ebf1 is required for suppressing the Muller cell fate during retinogenesis and important for the correct topographic projection of RGC axons at the optic chiasm.
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