Activity, regulation, copy number and function in the glyoxalase system.
Coventry, United Kingdom. In Biochem Soc Trans, 2014
Human GLO1 has MRE (metal-response element), IRE (insulin-response element), E2F4 (early gene 2 factor isoform 4), AP-2α (activating enhancer-binding protein 2α) and ARE (antioxidant response-element) regulatory elements and is a hotspot for copy number variation.
Unraveling the genetics of otitis media: from mouse to human and back again.
Australia. In Mamm Genome, 2011
Single-gene mouse mutants with OM have identified a number of genes, namely, Eya4, Tlr4, p73, MyD88, Fas, E2f4, Plg, Fbxo11, and Evi1, as potential and biologically relevant candidates for human disease.