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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Integral membrane protein 2C

E25, Itm2A, Itm2C, Integral membrane protein 2A
Top mentioned proteins: FBD, ACID, SET, CAN, P10
Papers using E25 antibodies
Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning
Bevan Michael J. et al., In The Journal of Experimental Medicine, 1988
... lck-ITM2A transgenic mice were generated as ...
Papers on E25
Assessing Readiness for En Pointe in Young Ballet Dancers.
Kruse et al., In Pediatr Ann, Feb 2016
Loss of ITM2A, a novel tumor suppressor of ovarian cancer through G2/M cell cycle arrest, is a poor prognostic factor of epithelial ovarian cancer.
Lee et al., Seoul, South Korea. In Gynecol Oncol, Jan 2016
OBJECTIVE: Integral membrane protein 2A (ITM2A) is a type 2 transmembrane protein of unknown function.
Potential of aryl-urea-benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease.
Guccione et al., İstanbul, Turkey. In Eur J Med Chem, Oct 2015
The result showed that all the synthesized compounds exhibited inhibitory activity on both AChE and BuChE with 1-(4-(5-bromobenzofuran-2-yl)thiazol-2-yl)-3-(2-fluorophenyl)urea (e25, IC50 value of 3.85 μM) and 1-(4-iodophenyl)-3-(4-(5-nitrobenzofuran-2-yl)thiazol-2-yl)urea (e38, IC50 value of 2.03 μM) as the strongest inhibitors against AChE and BuChE, respectively.
The C. elegans UNC-23 protein, a member of the BCL-2-associated athanogene (BAG) family of chaperone regulators, interacts with HSP-1 to regulate cell attachment and maintain hypodermal integrity.
Moerman et al., Colombia. In Worm, Apr 2015
We have isolated missense mutations in the ATPase domain of the C. elegans heat shock 70 protein, HSP-1 that suppress the phenotype exhibited by unc-23(e25) mutant hermaphrodites and we show that UNC-23 and HSP-1 interact in a yeast-2-hybrid system.
Maxillo-Mandibular Cemento-ossifying Fibroma: A Rare Case Report.
Reddy et al., Vikārābād, India. In J Maxillofac Oral Surg, Mar 2015
Majority of lesions occur in the mandible and only few cases of COFs of the maxillary sinus and bilateral COFs of the mandible have been reported in literature (Dinkar et al. in IJDA 2(4):45-47, 2010; Tamiolakis et al. in Acta Stomatol Croat 39(3):319-321, 2005; Hamner et al. in Oral Surg Oral Med Oral Pathol 26(4):579-587, 1968; Gunaseelan et al. in Oral Med Oral Pathol Oral Radiol Endod 104:e21-e25, 2007).
A 5.8 Mb interstitial deletion on chromosome Xq21.1 in a boy with intellectual disability, cleft palate, hearing impairment and combined growth hormone deficiency.
Bozzola et al., Novara, Italy. In Bmc Med Genet, 2014
This maternally inherited 5.8 Mb rearrangement encompasses 14 genes, including BRWD3 (involved in X-linked intellectual disability), TBX22 (a gene whose alterations have been related to the presence of cleft palate), POU3F4 (mutated in X-linked deafness) and ITM2A (a gene involved in cartilage development).
Meta-analysis of differentially expressed genes in ankylosing spondylitis.
Song et al., Seoul, South Korea. In Genet Mol Res, 2014
The upregulated gene with the largest effect size (ES; -1.2628, P = 0.020951) was integral membrane protein 2A (ITM2A), which is expressed by CD4+ T cells and plays a role in activation of T cells.
Analyzing glycan-binding patterns with the ProfilePSTMM Tool.
Aoki-Kinoshita, Hachiōji, Japan. In Methods Mol Biol, 2014
It implements the probabilistic model previously described by Aoki-Kinoshita et al. (Bioinformatics 22:e25-e34, 2006).
The integral membrane protein ITM2A, a transcriptional target of PKA-CREB, regulates autophagic flux via interaction with the vacuolar ATPase.
Park et al., Wŏnju, South Korea. In Autophagy, 2014
Here, we report that the integral membrane protein ITM2A expression is positively regulated by PKA-CREB signaling and ITM2A expression interferes with autophagic flux by interacting with vacuolar ATPase (v-ATPase).
Proteomics analysis of altered cellular metabolism induced by insufficient copper level.
Bondarenko et al., Thousand Oaks, United States. In J Biotechnol, 2014
In contrast, proteins such as syntenin (SDCBP) and integral membrane 2C (ITM2C) showed altered expression patterns toward the end of culture duration, after lactate divergence had occurred.
Autographa californica multiple nucleopolyhedrovirus orf132 encodes a nucleocapsid-associated protein required for budded-virus and multiply enveloped occlusion-derived virus production.
Li et al., Wuhan, China. In J Virol, 2014
However, viral DNA replication and the expression of late genes vp39 and odv-e25 and a reporter gene under the control of the very late gene p10 promoter were unaffected.
Itm2a expression in the developing mouse first lower molar, and the subcellular localization of Itm2a in mouse dental epithelial cells.
Sakai et al., Fukuoka, Japan. In Plos One, 2013
Itm2a is a type II transmembrane protein with a BRICHOS domain.
Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells.
Ho et al., Boston, United States. In Plos One, 2013
The integral membrane protein 2a (Itm2a) is one of the BRICHOS domain-containing proteins and is structurally related to Itm2b and Itm2c.
Significance of hyponatremia in heart failure.
O'Connor et al., Brescia, Italy. In Heart Fail Rev, 2012
American Heart Association, Dallas, 2007; Stewart et al. in Eur J Heart Fail 4:361-371, 2002), is a common phenomenon in patients with heart failure, with an incidence of 20-25% (Krumholz et al. in Arch Intern Med 157:e99-e104, 1997; Rosamond et al. in Circulation 117(4):e25-e146, 2008; Adrogue and Madias in N Engl J Med 342:1581-1589, 2000) and seems to be of prognostic importance in patients with heart failure (Luca et al. in Am J Cardiol 96:19L-23L, 2005; Gheorghiade et al. in Eur Heart J 28:980-988, 2007; Gheorghiade et al. in Arch Intern Med 167:1998-2005, 2007).
Public access defibrillators and fire extinguishers: are comparisons reasonable?
Sayre et al., Columbus, United States. In Prog Cardiovasc Dis, 2008
Sudden cardiac death is a major cause of mortality in the United States of America (Circulation 2008;117:e25-146) with approximately 310000 deaths related to coronary heart disease occurring in emergency departments or in the prehospital environment annually.
Expression and regulation of type II integral membrane protein family members in mouse male reproductive tissues.
Yang et al., Xiamen, China. In Endocrine, 2007
Both Itm2a and Itm2c were not detected in the epididymis and vas deferens during sexual maturation.
In vitro studies on Itm2a reveal its involvement in early stages of the chondrogenic differentiation pathway.
Merregaert et al., Antwerp, Belgium. In Biol Cell, 2004
Results support the involvement of Itm2a in the early stages of chondrogenesis in vitro.
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