Discovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cells
In Cell death and differentiation, 2008
... following sources: Akt, pAkt(T308), pAkt(S473) and pGSK3-β(S9) (Cell Signaling, Danvers, MA), mTOR (Millipore, Temecula, CA), E-cadherin (BD Biosciences, San José, CA), GAPDH ... the cytoskeleton, and cancer cell invasion
In Oncogenesis, 2008
... Antibodies used were: mouse anti-E-cadherin, anti-β-catenin, and anti-p120-catenin (BD, Heidelberg, Germany), rabbit anti-phospho-MLC and anti-E-cadherin pAbs (Cell Signaling, Danvers, MA, USA), rabbit ... Claudin-1, -2, -3, -4, -5, and -7 in usual interstitial pneumonia and sarcoidosismore suppliers
In International Journal of Molecular Sciences, 2008
... The slides were stained with antibodies: Snail-1 (rabbit polyclonal, Ab 85931, 1:150, Abcam), E-cadherin (mouse monoclonal, M3612, 1:50, Dako) and claudin-1 (mouse monoclonal, ...
Tissue invasion and metastasis: Molecular, biological and clinical perspectives.
Cardiff, United Kingdom. In Semin Cancer Biol, 09 May 2015
This review lists the disruption of E-cadherin and tight junctions, key signaling pathways, including urokinase type plasminogen activator (uPA), phosphatidylinositol 3-kinase/v-akt murine thymoma viral oncogene (PI3K/AKT), focal adhesion kinase (FAK), β-catenin/zinc finger E-box binding homeobox 1 (ZEB-1) and transforming growth factor beta (TGF-β), together with inactivation of activator protein-1 (AP-1) and suppression of matrix metalloproteinase-9 (MMP-9) activity as key targets and the use of phytochemicals, or natural products, such as those from Agaricus blazei, Albatrellus confluens, Cordyceps militaris, Ganoderma lucidum, Poria cocos and Silybum marianum, together with diet derived fatty acids gamma linolenic acid (GLA) and eicosapentanoic acid (EPA) and inhibitory compounds as useful approaches to target tissue invasion and metastasis as well as other hallmark areas of cancer.
Genetics of Breast Cancer: A Topic in Evolution.
More papers using
Seattle, United States. In Ann Oncol, Feb 2015
Up to 25% of hereditary cases are due to a mutation in one of the few identified rare, but highly penetrant genes (BRCA1, BRCA2, PTEN, TP53, CDH1, and STK11), which confer up to an 80% lifetime risk of breast cancer.
NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
In Journal of Experimental & Clinical Cancer Research : CR, 2003
... ERK (Tyr 204), phosphorylated JNK (Thr183/Tyr185), phosphorylated p65, p50, p38, Snail, SIP-1/ZEB-2, Twist, β-catenin, and E-cadherin were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ... Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.
In PLoS ONE, 2002
... Santa Cruz (Santa Cruz, CA), anti-HA, anti-FLAG (M2), anti-actin, anti-nucleolin from Sigma-Aldrich (St Louis, MO), anti-E-cadherin from BD Biosciences (San Diego, CA), anti-N-cadherin ... The CD16+ (FcγRIII+) Subset of Human Monocytes Preferentially Becomes Migratory Dendritic Cells in a Model Tissue Setting
In The Journal of Experimental Medicine, 2001
... purified mAbs to CD3, CD14, CD19, CD36, CD64, CD86, HLA-DR, HLA-DP (all from BD Biosciences), E-cadherin (Santa Cruz Biotechnology, Inc.), and IgM nonbinding ...