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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Tripartite motif containing 62

ductal epithelium-associated RING Chromosome 1, DEAR1
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Top mentioned proteins: Trim, SNAIL, ACID, Smad3, erbB-2
Papers on ductal epithelium-associated RING Chromosome 1
DEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticity.
Review
Killary et al., Houston, United States. In Cancer Res, 2014
This review will highlight the role of the novel TRIM protein DEAR1 (annotated as TRIM62) in the regulation of apical-basal polarity and acinar morphogenesis as well as its function as a chromosome 1p35 tumor suppressor and negative regulator of TGFβ-driven epithelial-mesenchymal transition (EMT).
The Arabidopsis transcriptional repressor ERF9 participates in resistance against necrotrophic fungi.
Yamaguchi et al., Sapporo, Japan. In Plant Sci, 2013
We previously isolated the Arabidopsis DEAR1 (DREB AND EAR MOTIF PROTEIN 1) regulator and showed that its overexpression DEAR1 (DEAR1ox) resulted in a dwarf phenotype and lesion-like cell death, accompanied by elevated expression of PR (PATHOGENESIS-RELATED) genes.
DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition.
Killary et al., Houston, United States. In Cancer Discov, 2013
We report that DEAR1 (annotated as TRIM62) is a chromosome 1p35 tumor suppressor that undergoes mutation, copy number variation, and loss of expression in human tumors.
Characterization of TRIM62 as a RING finger E3 ubiquitin ligase and its subcellular localization.
Yang et al., Wuhan, China. In Biochem Biophys Res Commun, 2013
TRIM62, also named DEAR1, is a member of the TRIM/RBCC family, which includes proteins with conserved RING finger, B-box and coiled-coil domains.
DEAR1, a transcriptional repressor of DREB protein that mediates plant defense and freezing stress responses in Arabidopsis.
Yamaguchi et al., Sapporo, Japan. In J Plant Res, 2009
The Arabidopsis DEAR1 (DREB and EAR motif protein 1; At3g50260) gene encodes a protein containing significant homology to the DREB1/CBF (dehydration-responsive element binding protein 1/C-repeat binding factor) domain and the EAR (ethylene response factor-associated amphiphilic repression) motif.
DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer.
GeneRIF
Killary et al., Houston, United States. In Plos Med, 2009
The evidence for the genetic alteration and loss of expression of DEAR1 in breast cancer and for the functional role of DEAR1 in the dominant regulation of acinar morphogenesis in 3D culture
A new tumor suppressor that regulates tissue architecture.
GeneRIF
Muthuswamy, Toronto, Canada. In Plos Med, 2009
DEAR1 is a predictive biomarker for early onset breast cancer.
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