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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Drebrin 1

Drebrin, drebrin A, drebrin E
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on Drebrin
Drebrin A expression is altered after pilocarpine-induced seizures: time course of changes is consistent for a role in the integrity and stability of dendritic spines of hippocampal granule cells.
Ferhat et al., Marseille, France. In Hippocampus, 2012
our results indicate that in vivo drebrin A is not critical for spinogenesis and morphogenesis but instead is consistent with an involvement in synaptic structural integrity, stabilization, and function.
Hippocampal drebrin loss in mild cognitive impairment.
Mufson et al., Chicago, United States. In Neurodegener Dis, 2011
The results of this study showed that Hippocampal drebrin loss in mild cognitive impairment.
High expression of cytoskeletal protein drebrin in TEL/AML1pos B-cell precursor acute lymphoblastic leukemia identified by a novel monoclonal antibody.
Hrusak et al., Praha, Czech Republic. In Leuk Res, 2011
High expression of cytoskeletal protein drebrin is associated with TEL/AML1pos B-cell precursor acute lymphoblastic leukemia
Low accumulation of drebrin at glutamatergic postsynaptic sites on GABAergic neurons.
Shirao et al., Maebashi, Japan. In Neuroscience, 2010
The density of drebrin-positive glutamatergic synapses formed on GABAergic neurons is lower than those on glutamatergic neurons.
Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphoma.
Sander et al., Huddinge, Sweden. In Plos One, 2009
Data show that DBN1, SETMAR and HIG2 are direct transcriptional targets of the SOX11 protein.
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