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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

DNA-damage regulated autophagy modulator 2

DRAM2, Pro-180, TMEM77
Top mentioned proteins: DRAM, p53, V1a, POLYMERASE, ACID
Papers on DRAM2
Disease Expression in Autosomal Recessive Retinal Dystrophy Associated With Mutations in the DRAM2 Gene.
Webster et al., Manchester, United Kingdom. In Invest Ophthalmol Vis Sci, Jan 2016
PURPOSE: To determine the disease course of retinal dystrophy caused by recessive variants in the DRAM2 (damage-regulated autophagy modulator 2) gene.
Biallelic mutations in the autophagy regulator DRAM2 cause retinal dystrophy with early macular involvement.
Ali et al., Leeds, United Kingdom. In Am J Hum Genet, Jul 2015
Affected individuals were found to harbor disease-causing variants in DRAM2 (DNA-damage regulated autophagy modulator protein 2).
Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population.
Perola et al., Helsinki, Finland. In Plos One, 2014
near the damage-regulated autophagy modulator 2 gene DRAM2 associated with NSTEMI (rs656843; odds ratio 1.57, P = 3.11 × 10-10) in the case-control analysis with a consistent but not statistically significant effect in the prospective cohort (rs656843; hazard ratio 1.13, P = 0.43).
MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia.
Chen et al., Guangzhou, China. In Autophagy, 2014
Furthermore, we identified DRAM2 (DNA-damage regulated autophagy modulator 2), a critical regulator of autophagy, as a novel target that was at least partly responsible for the function of MIR125B1 involved in autophagy.
The expression of damage-regulated autophagy modulator 2 (DRAM2) contributes to autophagy induction.
Park et al., Wŏnju, South Korea. In Mol Biol Rep, 2012
The expression of damage-regulated autophagy modulator 2 (DRAM2) contributes to autophagy induction.
Search for transmembrane protein in gastric cancer by the Escherichia coli ampicillin secretion trap: expression of DSC2 in gastric cancer with intestinal phenotype.
Yasui et al., Hiroshima, Japan. In J Pathol, 2010
Quantitative reverse transcription-polymerase chain reaction analysis of these candidates revealed that ZDHHC14, BST2, DRAM2, and DSC2 were expressed much more highly in GC than in 14 kinds of normal tissues.
Reduced expression of DRAM2/TMEM77 in tumor cells interferes with cell death.
Park et al., Wŏnju, South Korea. In Biochem Biophys Res Commun, 2010
reduced expression of DRAM2 may contribute to enhanced cell survival in tumor cells.
Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy.
Ryan et al., Glasgow, United Kingdom. In Cell Cycle, 2009
DRAM2 is different from DRAM as it not induced by p53 or p73. DRAM2 is also a lysosomal protein, its overexpression does not modulate autophagy.
Alphavirus minus-strand RNA synthesis: identification of a role for Arg183 of the nsP4 polymerase.
Sawicki et al., Toledo, United States. In J Virol, 2002
We conclude that Arg183 within the Pro180-Asn-Ile-Arg-Ser184 sequence of the SIN nsP4 polymerase contributes to the efficient initiation of minus strands or the formation of its replicase and that a host factor(s) participates in this event.
Amino acid deletions in loop C of the chlorophyll a-binding protein CP47 alter the chloride requirement and/or prevent the assembly of photosystem II.
Eaton-Rye et al., Dunedin, New Zealand. In Plant Mol Biol, 2000
The deletion between Gly-176 and Pro-180, located around the middle of loop C, produced an obligate photoheterotroph that could not assemble functional PSII centers.
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