A Puckered Singlet Cyclopentane-1,3-diyl: Detection of the Third Isomer in Homolysis.
Hiroshima, Japan. In Chemistry, Feb 2016
UNASSIGNED: In the photochemical denitrogenation of 1,4-diaryl-2,3-diazabicyclo[2.2.1]heptane (AZ6) bearing sterically hindered substituents, a curious new absorption band at about 450 nm was observed under low-temperature matrix conditions, together with the previously well-characterized planar singlet diradical pl-(1) DR6 with λmax =≈580 nm.
Structural determinants of DISC function: new insights into death receptor-mediated apoptosis signalling.
Galway, Ireland. In Pharmacol Ther, 2013
Eight members of the death receptor family have been identified in humans, which can be divided into four structurally homologous groups or clades, namely: the p75(NTR) clade (consisting of ectodysplasin A receptor, death receptor 6 (DR6) and p75 neurotrophin (NTR) receptor); the tumour necrosis factor receptor 1 clade (TNFR1 and DR3), the CD95 clade (CD95/FAS) and the TNF-related apoptosis-inducing ligand receptor (TRAILR) clade (TRAILR1 and TRAILR2).
Harnessing tumor necrosis factor receptors to enhance antitumor activities of drugs.
Córdoba, Spain. In Chem Res Toxicol, 2011
Cell death involving DR is mediated by the superfamily of tumor necrosis factor receptor (TNF-R) which includes TNF-R type I, CD95, DR3, TNF-related apoptosis-inducing ligand (TRAIL) receptor-1 (TRAIL-R1) and -2 (TRAIL-R2), DR6, ectodysplasin A (EDA) receptor (EDAR), and the nerve growth factor (NGF) receptor (NGFR).
Tyrosine phosphorylation and CD95: a FAScinating switch.
Heidelberg, Germany. In Cell Cycle, 2009
Death receptors are a subfamily of the TNF receptor superfamily, which includes the TNF receptor-I (TNFR1), TRAMP, DR3/APO-3, TRAIL-receptor 1 (TRAIL-R1/DR4), TRAIL-receptor 2 (TRAIL-R1/DR5), DR6 and CD95 (Fas/Apo-1).