Unravelling the immunological roles of dipeptidyl peptidase 4 (DPP4) activity and/or structure homolog (DASH) proteins.
Stuttgart, Germany. In Clin Exp Immunol, Jan 2016
Apart from DPP4, DASH proteins include fibroblast activation protein alpha (FAP), dipeptidyl peptidase 8 (DPP8), dipeptidyl peptidase 9 (DPP9), dipeptidyl peptidase 4-like protein 1 (DPL1, DPP6, DPPX L, DPPX S), dipeptidyl peptidase 4-like protein 2 (DPL2, DPP10) from the DPP4-gene family S9b and structurally unrelated enzyme dipeptiyl peptidase 2 (DPP2), displaying DPP4-like activity.
The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis.
Antwerp, Belgium. In Front Immunol, 2014
In this review, we provide a comprehensive discussion on the role of prolyl-specific peptidases DPPIV, FAP, DPP8, DPP9, dipeptidyl peptidase II, prolyl carboxypeptidase, and prolyl oligopeptidase in the immune system and its diseases.