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Transcription factor Dp family, member 3

DP4, E2F-like
This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.[provided by RefSeq, May 2010] (from NCBI)
Top mentioned proteins: CAN, CRTH2, HAD, Transcription Factor DP1, ACID
Papers using DP4 antibodies
The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.
Karagiannis Sophia N., In PLoS ONE, 2008
... HLA-DP4/hCD4 transgenic H-2 class II (IAβ)/mCD4-KO ...
About human tumor antigens to be used in immunotherapy
Debets Reno et al., In Clinical and Developmental Immunology, 2007
... /DP4 peptide and sorted on IFNγ secreting CD4+ T cells by FACSVantage flow cytometer (BD Biosciences) as described earlier [ ...
Papers on DP4
Short Peptide Vaccine Induces CD4+ T Helper Cells in Patients with Different Solid Cancers.
Kaempgen et al., Erlangen, Germany. In Cancer Immunol Res, Jan 2016
The two peptides were recognized by HLA-DP4- and HLA-DR-restricted TH1 cells.
Stereochemical Studies of the Karlotoxin Class Using NMR Spectroscopy and DP4 Chemical-Shift Analysis: Insights into their Mechanism of Action.
Hamann et al., United States. In Angew Chem Int Ed Engl, Jan 2016
After publication of karlotoxin 2 (KmTx2; 1), the harmful algal bloom dinoflagellate Karlodinium sp. was collected and scrutinized to identify additional biologically active complex polyketides.
Beyond DP4: an Improved Probability for the Stereochemical Assignment of Isomeric Compounds using Quantum Chemical Calculations of NMR Shifts.
Sarotti et al., Rosario, Argentina. In J Org Chem, Jan 2016
The DP4 probability is one of the most sophisticated and popular approaches for the stereochemical assignment of organic molecules using GIAO NMR chemical shift calculations when only one set of experimental data is available.
Ikaros, Helios, and Aiolos protein levels increase in human thymocytes after β selection.
Yankee et al., Kansas City, United States. In Immunol Res, Jan 2016
In each group of patients, CD3(-) ISP and DP thymocytes were subdivided into ISP1, ISP2, DP1, DP2, DP3, DP4, and DP5 developmental stages according to their expression of CD28, CD44, CD1a, CD7, CD45RO, and CD38.
Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY-cleaving peptidases and potential drug interactions in CNS and Periphery.
von Hörsten et al., Stuttgart, Germany. In J Neurochem, Dec 2015
The bioactivity of neuropeptide Y (NPY) is either N-terminally modulated with respect to receptor selectivity by dipeptidyl peptidase 4 (DP4)-like enzymes or proteolytic degraded by neprilysin or meprins, thereby abrogating signal transduction.
Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions.
Rajarathnam et al., Galveston, United States. In Biochem J, Dec 2015
To resolve these issues, we characterized the binding of a series of heparin-derived oligosaccharides [heparin disaccharide (dp2), heparin tetrasaccharide (dp4), heparin octasaccharide (dp8) and heparin 14-mer (dp14)] to the wild-type (WT) dimer and a designed monomer using solution NMR spectroscopy.
In vitro digestion and fermentation properties of linear sugar-beet arabinan and its oligosaccharides.
Han et al., Ch'ŏngju, South Korea. In Carbohydr Polym, Nov 2015
DP4 (20.1%), and DP5 (1.16%).
Comparison of experimental and DFT-calculated NMR chemical shifts of 2-amino and 2-hydroxyl substituted phenyl benzimidazoles, benzoxazoles and benzothiazoles in four solvents using the IEF-PCM solvation model.
Reutens et al., Australia. In Magn Reson Chem, Nov 2015
The DP4 probability measures were also used to compare the experimental and calculated chemical shifts for each compound in the four solvents.
Permeation of Therapeutic Drugs in Different Formulations across the Airway Epithelium In Vitro.
Fröhlich et al., Graz, Austria. In Plos One, 2014
Compounds were applied in solution and as aerosols generated by MicroSprayer IA-1C Aerosolizer or by DP-4 Dry Powder Insufflator using fluorescein and rhodamine 123 as model compounds.
Genetics and physiology of cell wall polysaccharides in the model C4 grass, Setaria viridis spp.
Burton et al., Adelaide, Australia. In Bmc Plant Biol, 2014
The fine structures of the (1,3;1,4)-β-glucan, as denoted by the ratio of cellotriosyl to cellotetraosyl residues (DP3:DP4 ratio) was assessed by chromatography (HPLC and HPAEC-PAD).
[Effects of TFDP3 on regulating the autophagy and apoptosis of LNCaP cells].
Hao et al., Xi'an, China. In Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2012
Data show that TFDP3 upregulates the expression of autophagy gene LC3B and inhibits E2F1-induced apoptosis, and may play an important role in prostate cancer.
E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit.
La Thangue et al., Oxford, United Kingdom. In Cell Death Differ, 2011
DP-4 downregulating E2F-1 activity and contributes to a new pRb-independent mechanism for regulating cell cycle progression.
Clinical effectiveness and cost-effectiveness of stem cell transplantation in the management of acute leukaemia: a systematic review.
Chen et al., Birmingham, United Kingdom. In Health Technol Assess, 2010
Included randomised controlled trials (RCTs) and donor versus no donor (DvND) studies were mapped to the evidence covered in existing systematic reviews and meta-analyses according to a framework of 12 decision problems (DPs): DP1 related to SCT in adults with AML in first complete remission (CR1); DP2 to adults with AML in second or subsequent remission or with refractory disease (CR2+); DP3 to children with AML in CR1; DP4 to children with AML in CR2+; DP5 to adults with ALL in CR1; DP6 to adults with ALL in CR2+; DP7 to children with ALL in CR1; DP8 to children with ALL in CR2+; DP9 to comparison of different sources of stem cells in transplantation; DP10 to different conditioning regimens; DP11 to the use of purging in autologous SCT; and DP12 to the use of T-cell depletion in allogeneic SCT.
Human TFDP3, a novel DP protein, inhibits DNA binding and transactivation by E2F.
Chen et al., Beijing, China. In J Biol Chem, 2007
TFDP3, a novel DP protein, inhibits DNA binding and transactivation by E2F
Upregulation of E2F transcription factors in chemically induced mouse skin tumors.
Mukhtar et al., Cleveland, United States. In Int J Oncol, 1999
E2Fs are a family of heterodimeric transcription factors composed of E2F-like and DP-like subunits.
Phylogenetic, paleodemographic, and taphonomic implications of Victoriapithecus deciduous teeth from Maboko, Kenya.
Benefit, Carbondale, United States. In Am J Phys Anthropol, 1994
Victoriapithecus also differs from cercopithecids in having less elongated deciduous premolars, a dp3 metacone set mesial to a very small hypocone, a dp4 crista obliqua, and a dp4 hypoconulid.
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties.
Blanar et al., Boston, United States. In Cell, 1992
An expression vector was modified to permit the rapid synthesis of purified, 32P-labeled, glutathione S-transferase (GST)-retinoblastoma (RB) fusion proteins.
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F.
Fattaey et al., United States. In Cell, 1992
These properties suggest that RBP3 encodes E2F, or an E2F-like protein.
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