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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Docking protein 4

Papers on Dok-4
Dok4 is involved in Schwann cell myelination and axonal interaction in vitro.
Decker et al., Paris, France. In Glia, 2011
Dok4 is a novel player in Schwann cell-axon interaction and is required at early stages of myelination; it also aids Schwann cell migration and proliferation.
Dok-4 is a novel negative regulator of T cell activation.
Nun├Ęs et al., Marseille, France. In J Immunol, 2009
Dok-4 represents a novel negative regulator of T cells
Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells.
O'Byrne et al., Dublin, Ireland. In Clin Lung Cancer, 2008
Epigenetic regulation of DOK4 expression is associated with non-small-cell lung cancer.
DOK4/IRS-5 expression is altered in clear cell renal cell carcinoma.
Gray et al., Dublin, Ireland. In Int J Cancer, 2007
IRS-5 (DOK4) is significantly upregulated in 90% of examined clear cell RCCs. Studies on this gene has shown that it is regulated through chromatin remodeling in kidney cells
Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase.
Takahashi et al., Nagoya, Japan. In J Cell Sci, 2006
Results suggest that Dok-4, through activation of the Rap1-ERK1/2 pathway, regulates GDNF-mediated neurite outgrowth during neuronal development.
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