Plasma Autoantibodies Associated with Basal-like Breast Cancers.
Warsaw, Poland. In Cancer Epidemiol Biomarkers Prev, Sep 2015
RESULTS: We identified 13 AAbs (CTAG1B, CTAG2, TP53, RNF216, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity.
Expression and significance of DOK2 in colorectal cancer.
Wuhan, China. In Oncol Lett, 2015
A reduction in the levels of docking protein 2 (DOK2) expression has previously been reported in lung adenocarcinoma and gastric cancer, indicating that this protein acts as a tumor suppressor in solid tumors.
Maternal preconception body mass index and offspring cord blood DNA methylation: exploration of early life origins of disease.
Chicago, United States. In Environ Mol Mutagen, 2014
Some of the other CpG site annotated genes appear to be critical to the development of cancers and cardiovascular diseases (i.e., WNT16, C18orf8, ANGPTL2, SAPCD2, ADCY3, PRR16, ERBB2, DOK2, PLAC1).
Pattern-recognition receptor signaling regulator mRNA expression in humans and mice, and in transient inflammation or progressive fibrosis.
München, Germany. In Int J Mol Sci, 2012
We therefore determined the mRNA expression levels of A20, CYLD, DUBA, ST2, CD180, SIGIRR, TANK, SOCS1, SOCS3, SHIP, IRAK-M, DOK1, DOK2, SHP1, SHP2, TOLLIP, IRF4, SIKE, NLRX1, ERBIN, CENTB1, and Clec4a2 in human and mouse solid organs.
Reconstruction of an integrated genome-scale co-expression network reveals key modules involved in lung adenocarcinoma.
Tehrān, Iran. In Plos One, 2012
DLGAP5, BIRC5, PSMD2, Src, TTK, SENP2, PSMD2, DOK2, FUS and etc.) in the modules.
Haplo-insufficiency: a driving force in cancer.
Boston, United States. In J Pathol, 2011
Due to the challenges of identifying haplo-insufficient TSGs by human genetics analysis alone, mouse models play a pivotal role in firmly establishing the haplo-insufficiency of a gene, as in the recent identification of DOK2 as a haplo-insufficient lung TSG.