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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Dj-1beta

dj-1beta, DJ-1b
Top mentioned proteins: DJ-1, AGE, Ros, CAN, catalase
Papers on dj-1beta
Novel glyoxalases from Arabidopsis thaliana.
Park et al., Taej┼Ćn, South Korea. In Febs J, 2013
We examined six Arabidopsis thaliana genes from the DJ-1/PfpI superfamily for similarity to the recently characterized bacterial and animal glyoxalases.
Conservation of oxidative protein stabilization in an insect homologue of parkinsonism-associated protein DJ-1.
GeneRIF
Wilson et al., Lincoln, United States. In Biochemistry, 2012
the oxidation of conserved cysteine residue to its sulfinate form (Cys-SO(2)(-)) results in considerable thermal stabilization of both Drosophila DJ-1beta and human DJ-1
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function.
GeneRIF
Bonini et al., Philadelphia, United States. In Proc Natl Acad Sci U S A, 2010
Flies deleted for DJ-1 manifest similar defects as pink1 and parkin mutants: male sterility, shortened lifespan, and reduced climbing ability.
Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila.
Jacobs et al., Tampere, Finland. In Aging (albany Ny), 2010
The third prediction was tested in flies mutant for the gene dj-1beta.
Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation.
Impact
Jacobs et al., Tampere, Finland. In Cell Metab, 2009
It also rescued the locomotor defect and excess mitochondrial ROS production of flies mutated in dj-1beta, a Drosophila homolog of the human Parkinson's disease gene DJ1.
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging.
GeneRIF
Bonini et al., Philadelphia, United States. In Proc Natl Acad Sci U S A, 2006
Data show that human DJ-1 rescues flies mutant for DJ-1b; a conserved cysteine in is critical for antioxidant function, and suggest that overoxidation of DJ-1 with age and exposure to oxidants can cause inactivation.
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease.
GeneRIF
Bonini et al., Philadelphia, United States. In Curr Biol, 2005
DJ-1beta protein is biochemically responsive to oxidative stress, and mutant DJ-1 flies are selectively sensitive to environmental toxins associated with Parkinson's disease.
Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress.
GeneRIF
Min et al., Bethesda, United States. In Curr Biol, 2005
Loss-of-function DJ-1beta mutants demonstrated an extended survival of dopaminergic neurons and resistance to paraquat stress, but showed acute sensitivity to hydrogen peroxide treatment.
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