Conserved determinants of lentiviral genome dimerization.
Baltimore, United States. In Retrovirology, 2014
Dimerization of human immunodeficiency virus Type-1 (HIV-1) genomes is initiated by "kissing" interactions between GC-rich palindromic loop residues of a conserved hairpin (DIS), and is indirectly promoted by long-range base pairing between residues overlapping the gag start codon (AUG) and an upstream Unique 5' element (U5).
CATSPER-Related Male Infertility
Seattle, United States. In Unknown Journal, 2010
CLINICAL CHARACTERISTICS: CATSPER-related male infertility results from abnormalities in sperm and can be either CATSPER-related nonsyndromic male infertility (NSMI) or the deafness-infertility syndrome (DIS) when associated with non-progressive prelingual sensorineural hearing loss.
Dilated intercellular spaces as a marker of GERD.
Durham, United States. In Curr Gastroenterol Rep, 2009
Recently, biopsies established that subjects with heartburn and PPI-responsive NERD, like those with erosive esophagitis, have lesions within the esophageal epithelium known as dilated intercellular space (DIS).