Polymorphisms in DCDC2 and S100B associate with developmental dyslexia.
Huddinge, Sweden. In J Hum Genet, Jul 2015
We aimed at discovering single nucleotide variation present in known and new candidate genes for developmental dyslexia: CYP19A1, DCDC2, DIP2A, DYX1C1, GCFC2 (also known as C2orf3), KIAA0319, MRPL19, PCNT, PRMT2, ROBO1 and S100B.
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Boston, United States. In Nat Neurosci, 2014
Furthermore, we functionally validated these CpG associations and identified the nearby genes whose RNA expression was altered in AD: ANK1, CDH23, DIP2A, RHBDF2, RPL13, SERPINF1 and SERPINF2.
A theoretical molecular network for dyslexia: integrating available genetic findings.
Nijmegen, Netherlands. In Mol Psychiatry, 2011
We found that 10 of the 14 dyslexia candidate genes (ROBO1, KIAA0319, KIAA0319L, S100B, DOCK4, FMR1, DIP2A, GTF2I, DYX1C1 and DCDC2) fit into a theoretical molecular network involved in neuronal migration and neurite outgrowth.
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines.
Chicago, United States. In Genome Biol, 2010
The most intriguing trans signal was obtained for SNP rs10876043 in the disco-interacting protein 2 homolog B gene (DIP2B, previously postulated to play a role in DNA methylation), that had a genome-wide significant association with the first principal component of patterns of methylation; however, we found only modest signal of trans-acting associations overall.
DIP2A functions as a FSTL1 receptor.
Boston, United States. In J Biol Chem, 2010
These data indicate that DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1.