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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Cyclin D-type binding-protein 1

DIP1, GCIP, DIPI
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009] (from NCBI)
Top mentioned proteins: PCNA, CAN, ACID, POLYMERASE, fibrillin-1
Papers on DIP1
miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis.
New
Schneider-Stock et al., Erlangen, Germany. In Inflamm Bowel Dis, Sep 2015
We identified 4 novel miR-26b targets (DIP1, MDM2, CREBBP, BRCA1).
DIP1 plays an antiviral role against DCV infection in Drosophila melanogaster.
New
Wu et al., Hefei, China. In Biochem Biophys Res Commun, Jun 2015
Disconnected Interacting Protein 1 (DIP1) is a dsRNA-binding protein that participates in a wide range of cellular processes.
Gαq protein carboxyl terminus imitation polypeptide GCIP-27 improves cardiac function in chronic heart failure rats.
Zhang et al., Chongqing, China. In Plos One, 2014
BACKGROUND: Gαq protein carboxyl terminus imitation polypeptide (GCIP)-27 has been shown to alleviate pathological cardiomyocyte hypertrophy induced by various factors.
miR-9 Modulates Osteosarcoma Cell Growth by Targeting the GCIP Tumor Suppressor.
Liu et al., Tianjin, China. In Asian Pac J Cancer Prev, 2014
Further study identified GCIP, a Grap2 and cyclin D interacting protein, as a direct target of miR- 9.
GCIP functions as a tumor suppressor in non-small cell lung cancer by suppressing Id1-mediated tumor promotion.
Chang et al., Tainan City, Taiwan. In Oncotarget, 2014
Grap2 and cyclin D1 interacting protein (GCIP) has been recognized as a putative tumor suppressor, but the molecular mechanisms underlying its anti-tumor properties remain undefined.
Guanidination of soluble lysine-rich cyanophycin yields a homoarginine-containing polyamide.
Steinbüchel et al., Münster, Germany. In Appl Environ Microbiol, 2014
In addition, the modified CGP could be digested in vitro using the cyanophycinase from Pseudomonas alcaligenes strain DIP1, yielding a new dipeptide consisting of aspartate and homoarginine.
Transmembrane transport of the Gαq protein carboxyl terminus imitation polypeptide GCIP-27.
Zhang et al., Chongqing, China. In Eur J Pharm Sci, 2013
The Gαq protein carboxyl terminus imitation polypeptide (GCIP)-27 has been shown to affect cardiac hypertrophy and vascular remodeling in various models both in vitro and in vivo.
Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.
GeneRIF
Nureki et al., Tokyo, Japan. In Embo J, 2012
The first structure of a free-standing human dominant-negative helix-loop-helix protein (DIP1) was reported. DIP1 adopts a V-shaped conformation, with N-terminal and C-terminal five-helix bundles connected by the HLH region.
Disconnected Interacting Protein 1 binds with high affinity to pre-tRNA and ADAT.
GeneRIF
Matthews et al., Houston, United States. In Biochem Biophys Res Commun, 2011
DIP1-c was shown to interact with ADAT, a tRNA deaminase that presumably modifies pre-tRNAs.
Production optimization of cyanophycinase ChpEal from Pseudomonas alcaligenes DIP1.
Steinbüchel et al., Münster, Germany. In Amb Express, 2010
Pseudomonas alcaligenes DIP1 produces an extracellular cyanophycinase (CphEal).
Gαq-protein carboxyl terminus imitation polypeptide GCIP-27 attenuates proliferation of vascular smooth muscle cells and vascular remodeling in spontaneously hypertensive rats.
Li et al., China. In Biol Pharm Bull, 2010
The present study was designed to explore the effects of a synthetic Gαq carboxyl terminus imitation peptide, namely GCIP-27, on vascular smooth muscle cells (VSMC) in vitro and vascular remodeling in spontaneous hypertensive rats (SHR).
High affinity, dsRNA binding by disconnected interacting protein 1.
GeneRIF
Matthews et al., Houston, United States. In Biochem Biophys Res Commun, 2010
the longest isoform of this protein, DIP1-c, exhibits a 500-fold preference for dsRNA over dsDNA of similar nucleotide sequence.
A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment.
GeneRIF
Park et al., Seoul, South Korea. In Cancer Res, 2010
It is proposed for the first time that Rad may promote carcinogenesis at least in part by inhibiting GCIP-mediated tumor suppression.
[Analysis of the structure and expression of the cluster of Drosophila melanogaster genes DIP1, CG32500, CG32819, and CG14476 in the flamenco gene region].
GeneRIF
Kim et al., In Genetika, 2009
Analysis of the structure and expression of the cluster of Drosophila melanogaster genes DIP1, CG32500, CG32819, and CG14476 in the flamenco gene region
Galphaq-protein carboxyl terminus imitation polypeptide (GCIP)-27 inhibits right ventricular hypertrophy induced by monocrotaline in rats.
Li et al., Chongqing, China. In Biol Pharm Bull, 2009
This study was to investigate the probable inhibitory effect of Galphaq-protein carboxyl terminus imitation polypeptide-27 (GCIP-27), the optimized form of GCIP, which is a competition candidate of the activated binding sites on Galphaq, on the right ventricular (RV) hypertrophy induced by monocrotaline (MCT) in rats.
[Analysis of the structure and expression of the DIP1 gene in Drosophila melanogaster strains mutant for the flamenco gene].
GeneRIF
Kim et al., In Genetika, 2009
the flamenco- phenotype may be associated with an alteration of DIP1 gene transcription, as in differentflamenco- strains the DIP1 gene expression is changed differently.
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