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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

Dicer, decoy receptor, DcR1, GHRH receptor
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, miR, V1a, Cdc4, Ribonuclease III
Papers using Dicer antibodies
GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation.
Xu Wenqing, In PLoS ONE, 2007
... The gene encoding the TLR4 decoy receptor, TV3, was cloned into the pAcGP67 vector (BD Biosciences) with the BamH I and ...
Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections.
Nait-Oumesmar Brahim, In PLoS ONE, 2006
... Dicer transgenic mice ( ...
Rapid and simple comparison of messenger RNA levels using real-time PCR.
Klefstrom Juha, In PLoS ONE, 2005
... (5B2H5) from Invitrogen (32-1700, Carlsbad, CA), anti-β-catenin antibody from BD Biosciences (610154, San Jose, CA), Dicer antibody from Abcam (ab14601, Cambridge, MA), anti-GSK3β ...
Papers on Dicer
AmiRNA Designer - new method of artificial miRNA design.
Blazewicz et al., Poznań, Poland. In Acta Biochim Pol, Feb 2016
MiRNAs are produced from their precursors by Dicer-dependent small RNA biogenesis pathway.
Serum levels of interleukin-18-binding protein isoform a: Clinical association with inflammation and pulmonary hypertension in systemic sclerosis.
Sato et al., Tokyo, Japan. In J Dermatol, Feb 2016
To address this issue, we herein determined serum levels of IL-18-binding protein isoform a (IL-18BPa), a soluble decoy receptor for IL-18, by enzyme-linked immunosorbent assay in 57 SSc patients and 20 healthy controls and evaluated their clinical correlation.
Screening of Pre-miRNA-155 Binding Peptides for Apoptosis Inducing Activity Using Peptide Microarrays.
Shin et al., Seoul, South Korea. In J Am Chem Soc, Feb 2016
Two peptides, which were identified based on the results of peptide microarray and in vitro Dicer inhibition studies, were found to inhibit generation of mature miRNA-155 catalyzed by Dicer and to enhance expression of miRNA-155 target genes in cells.
Dynamic distributions of long double-stranded RNA in Tetrahymena during nuclear development and genome rearrangements.
Yao et al., Taipei, Taiwan. In J Cell Sci, Feb 2016
Deficiency in RNAi pathway leads to abnormal aggregations of dsRNA in both the parental and new somatic nuclei, whereas accumulation of dsRNAs in the germline nuclei is only seen in the Dicer-like gene mutant.
Structural and functional insights into the fly microRNA biogenesis factor Loquacious.
Meister et al., Regensburg, Germany. In Rna, Feb 2016
UNASSIGNED: In the microRNA (miRNA) pathway, Dicer processes precursors to mature miRNAs.
Structure of Human DROSHA.
Woo et al., Seoul, South Korea. In Cell, Feb 2016
The overall structure of DROSHA is surprisingly similar to that of Dicer despite no sequence homology apart from the C-terminal part, suggesting that DROSHA may have evolved from a Dicer homolog.
Vulnerability of microRNA biogenesis in FTD-ALS.
Hornstein et al., Israel. In Brain Res, Feb 2016
Accordingly, potential insufficiencies of the 'microprocessor' complex, the nucleo-cytoplasmic export of miRNA precursors or their processing by Dicer were recently reported.
A-to-I editing of coding and non-coding RNAs by ADARs.
Nishikura, Philadelphia, United States. In Nat Rev Mol Cell Biol, Jan 2016
Conversely, recent studies indicate that ADAR1 forms a complex with Dicer to promote miRNA processing, revealing a new function of ADAR1 in the regulation of RNA interference.
Non-coding RNA in Spermatogenesis and Epididymal Maturation.
McLaughlin et al., Newcastle, Australia. In Adv Exp Med Biol, Dec 2015
Testicular germ and somatic cells express many classes of small ncRNAs, including Dicer-independent PIWI-interacting RNAs, Dicer-dependent miRNAs, and endogenous small interfering RNA.
The expanding world of small RNAs in plants.
Martienssen et al., New York City, United States. In Nat Rev Mol Cell Biol, Dec 2015
We also discuss the diversification of small-RNA-directed silencing pathways through the expansion of RNA-dependent RNA polymerases, DICER proteins and ARGONAUTE proteins.
Expression and functional roles of the chemokine receptor CXCR7 in acute myeloid leukemia cells.
Jo et al., Taejŏn, South Korea. In Blood Res, Dec 2015
BACKGROUND: The C-X-C chemokine receptor 7 (CXCR7) has been shown to be a decoy receptor for CXCR4 in certain cell types.
Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis.
Chong et al., Australia. In Nat Immunol, Nov 2015
To investigate if the microRNA (miRNA) pathway is required for dendritic cell (DC) development, we assessed the effect of ablating Drosha and Dicer, the two enzymes central to miRNA biogenesis.
Advances in treatment of achondroplasia and osteoarthritis.
Horton et al., Portland, United States. In Hum Mol Genet, Nov 2015
The first is a decoy receptor that competes for activating ligands.
Osteoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand Pathway.
Vasavada et al., New York City, United States. In Cell Metab, Aug 2015
We identified osteoprotegerin, a bone-related decoy receptor, as a β-cell mitogen.
Chimeric DCL1-Partnering Proteins Provide Insights into the MicroRNA Pathway.
Waterhouse et al., Sydney, Australia. In Front Plant Sci, 2014
In Arabidopsis thaliana, efficient microRNA (miRNA) production requires DICER-LIKE1 (DCL1) with the assistance of a partnering protein, DOUBLE-STRANDED RNA BINDING1 (DRB1) or DRB2.
Loss of dicer exacerbates cyclophosphamide-induced bladder overactivity by enhancing purinergic signaling.
Wang et al., Wuhan, China. In Am J Pathol, 2012
loss of Dicer may impair the expression of miRNAs that are capable of targeting P2x mRNAs.
Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells.
Mann et al., Australia. In Plos Genet, 2012
These studies reveal that reduced functional DNMT activity is not a salient feature of DICER1-deficient embryonic stem cells.
Functional importance of Dicer protein in the adaptive cellular response to hypoxia.
Marsden et al., Toronto, Canada. In J Biol Chem, 2012
functional deficiency of Dicer in chronic hypoxia is relevant to both HIF-alpha isoforms and hypoxia-responsive/HIF target genes, especially in the vascular endothelium.
A fluorescence correlation spectroscopy-based enzyme assay for human Dicer.
Hahn et al., Hamburg, Germany. In Biol Chem, 2012
The RNase activity of Dicer could be inhibited by substituting Ca 2 + for Mg 2 + .
Dicer1 ablation in the mouse epididymis causes dedifferentiation of the epithelium and imbalance in sex steroid signaling.
Sipilä et al., Turku, Finland. In Plos One, 2011
At the time of the final epididymal development, Dicer1 acts as a regulator of signaling pathways essential for maintaining epithelial cell differentiation.
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