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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Diazepam binding inhibitor

Diazepam Binding Inhibitor, peripheral benzodiazepine receptor, DBI, ACBP, peripheral-type benzodiazepine receptor
plays a role in the regulation of mitochondrial steroidogenesis and acyl-CoA metabolism [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, V1a, Rdl
Papers on Diazepam Binding Inhibitor
Translocator protein (TSPO) affects mitochondrial fatty acid oxidation in steroidogenic cells.
New
Selvaraj et al., Ithaca, United States. In Endocrinology, Feb 2016
UNASSIGNED: Translocator protein (TSPO), also known as the peripheral benzodiazepine receptor (PBR), is a highly conserved outer mitochondrial membrane protein present in specific sub-populations of cells within different tissues.
Plant Cytosolic Acyl-CoA-Binding Proteins.
New
Chye et al., Hong Kong, Hong Kong. In Lipids, Jan 2016
A gene family encoding six members of acyl-CoA-binding proteins (ACBP) exists in Arabidopsis and they are designated as AtACBP1-AtACBP6.
Recombinant expression, purification, and characterization of an acyl-CoA binding protein from Aspergillus oryzae.
New
Zeng et al., Tianjin, China. In Biotechnol Lett, Jan 2016
OBJECTIVES: To characterize biochemically the lipid metabolism-regulating acyl-CoA binding protein (ACBP) from the industrially-important fungus Aspergillus oryzae.
Mitochondrial translocator protein (TSPO) function is not essential for heme biosynthesis.
New
Selvaraj et al., United States. In J Biol Chem, Jan 2016
UNASSIGNED: Function of the mammalian translocator protein (TSPO; previously known as the peripheral benzodiazepine receptor/PBR) remains unclear as its presumed role in steroidogenesis and mitochondrial permeability transition established using pharmacological methods have been refuted in recent genetic studies.
Guwiyang Wurra-'Fire Mouse': a global gene knockout model for TSPO/PBR drug development, loss-of-function and mechanisms of compensation studies.
Review
New
Banati et al., Sydney, Australia. In Biochem Soc Trans, Sep 2015
The highly conserved 18-kDa translocator protein (TSPO) or peripheral benzodiazepine receptor (PBR), is being investigated as a diagnostic and therapeutic target for disease conditions ranging from inflammation to neurodegeneration and behavioural illnesses.
Structure of the mammalian TSPO/PBR protein.
Review
New
Zweckstetter et al., Göttingen, Germany. In Biochem Soc Trans, Sep 2015
The 3D structure of the 18-kDa transmembrane (TM) protein TSPO (translocator protein)/PBR (peripheral benzodiazepine receptor), which contains a binding site for benzodiazepines, is important to better understand its function and regulation by endogenous and synthetic ligands.
Long-chain acyl-CoA esters in metabolism and signaling: Role of acyl-CoA binding proteins.
Review
New
Færgeman et al., Odense, Denmark. In Prog Lipid Res, Jul 2015
This review summarizes the structural and functional properties of the various ACBDs, with special emphasis on the function of ACBD1, commonly known as ACBP.
The changing landscape in translocator protein (TSPO) function.
Review
New
Stocco et al., Ithaca, United States. In Trends Endocrinol Metab, Jul 2015
Translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor (PBR), is an outer mitochondrial membrane protein.
Minireview: translocator protein (TSPO) and steroidogenesis: a reappraisal.
Review
New
Tu et al., Lubbock, United States. In Mol Endocrinol, Apr 2015
The 18-kDa translocator protein (TSPO), also known as the peripheral benzodiazepine receptor, is a transmembrane protein in the outer mitochondrial membrane.
PET imaging studies show enhanced expression of mGluR5 and inflammatory response during progressive degeneration in ALS mouse model expressing SOD1-G93A gene.
Maxwell et al., United States. In J Neuroinflammation, 2014
METHODS: In vivo positron emission tomography (PET) imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) using [(18)F]FPEB ([(18)F]3-fluoro-5-(2-pyridylethynyl)benzonitrile) and inflammatory response using [(11)C]PBR28 (peripheral benzodiazepine receptor ligand 28) were done in an early and a late phase of neurodegeneration in four ALS mice expressing SOD1-G93A gene and four control base mice (C57/BL6).
The Tryptophan-Rich Sensory Protein (TSPO) is Involved in Stress-Related and Light-Dependent Processes in the Cyanobacterium Fremyella diplosiphon.
Montgomery et al., East Lansing, United States. In Front Microbiol, 2014
The tryptophan-rich sensory protein (TSPO) is a membrane protein, which is a member of the 18 kDa translocator protein/peripheral-type benzodiazepine receptor (MBR) family of proteins that is present in most organisms and is also referred to as Translocator protein 18 kDa.
Mouse TSPO in a lipid environment interacting with a functionalized monolayer.
GeneRIF
Lacapere et al., Paris, France. In Biochim Biophys Acta, 2012
different amino acid compositions and the location of the polyhistidine tag between bacterial and mouse TSPO could account for the formation of dimer versus tetramer, respectively
DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies.
GeneRIF
Sablitzky et al., Nottingham, United Kingdom. In J Biol Chem, 2012
DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies.
The expression of translocator protein in human thyroid cancer and its role in the response of thyroid cancer cells to oxidative stress.
GeneRIF
Vasko et al., Washington, D.C., United States. In J Endocrinol, 2012
Implication of TSPO in the thyroid cancer cell response to oxidative stress suggested its potential role in the regulation of thyroid cancer cell response to treatment with radioiodine.
Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling.
Impact
GeneRIF
Monyer et al., Heidelberg, Germany. In Cell Stem Cell, 2012
Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling.
[Apoptosis modulation by PMA occurs independently of TsPO expression in squamous cell carcinoma cells].
GeneRIF
Ruksha, In Patol Fiziol Eksp Ter, 2012
Apoptosis modulation by PMA occurs independently of TsPO expression in squamous cell carcinoma cells
SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU).
GeneRIF
Gery et al., Bethesda, United States. In Mol Vis, 2011
SLAT/Def6 plays a major role in the T cell-mediated autoimmune processes that bring about the inflammatory eye disease, experimental autoimmune uveitis.
Identification and purification of a protein that binds the yeast ARS consensus sequence.
Impact
Gasser et al., Lausanne, Switzerland. In Cell, 1991
The purified ARS consensus-binding protein (ACBP) recognizes the ARS consensus of the four genomic ARS elements tested, binding preferentially to the T-rich single strand.
Benzodiazepine receptor-mediated chemotaxis of human monocytes.
Impact
Paul et al., In Science, 1985
The chemotactic effects of benzodiazepine receptor agonists were blocked by the peripheral benzodiazepine receptor antagonist PK-11195, suggesting that these effects are mediated by the peripheral-type benzodiazepine receptor.
Diazepam-binding inhibitor: a neuropeptide located in selected neuronal populations of rat brain.
Impact
Guidotti et al., In Science, 1985
This polypeptide was termed diazepam-binding inhibitor (DBI).
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