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Amiloride binding protein 1

diamine oxidase, D-Amino-Acid Oxidase, DAO, histaminase
This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, V1a, catalase
Papers using diamine oxidase antibodies
Molecular and genetic characterization of an ornithine decarboxylase deficient chinese hamster cell line.
Valenzuela Jesus G., In PLoS Neglected Tropical Diseases, 1989
... Putrescine, 4-aminoantipyrine, diamine oxidase (DAO), horseradish peroxidase, L and D-ornithine were procured from Sigma Aldrich.
Papers on diamine oxidase
Moderate stress responses and specific changes in polyamine metabolism characterize Scots pine somatic embryogenesis.
Vuosku et al., Oulu, Finland. In Tree Physiol, Feb 2016
Cellular PA contents and the expression of the PA metabolism genes arginine decarboxylase (ADC), spermidine synthase (SPDS), thermospermine synthase (ACL5) and diamine oxidase (DAO) were analyzed, as well as the expression of catalase (CAT), DNA repair genes (RAD51, KU80) and autophagy-related genes (ATG5, ATG8) throughout the induction of somatic embryo formation in Scots pine SE cultures.
Effect of spermidine and its metabolites on the activity of pea seedlings diamine oxidase and the problems of biosensing of biogenic amines with this enzyme.
Rinken et al., Tartu, Estonia. In Enzyme Microb Technol, Jan 2016
In these biosensors, diamine oxidase from pea seedlings (PSAO), catalyzing the oxidation of various biogenic amines by dissolved oxygen is commonly used for the bio-recognition of amines.
In situ Click Chemistry for the Identification of a Potent D-Amino Acid Oxidase Inhibitor.
Sunazuka et al., In Chem Pharm Bull (tokyo), Jan 2016
We report in situ click chemistry screening with human D-amino acid oxidase (hDAO), which led to the identification of a more potent hDAO inhibitor.
Role of D-amino acid oxidase in the production of kynurenine pathway metabolites from D-tryptophan in mice.
Schwarcz et al., Baltimore, United States. In J Neurochem, Jan 2016
D-TRP can be converted to L-TRP by D-amino acid oxidase (D-AAO), and the same enzyme can produce D-kynurenine, a known bioprecursor of KYNA.
Effects of ABA and CaCl2 on GABA accumulation in fava bean germinating under hypoxia-NaCl stress.
Gu et al., Nanjing, China. In Biosci Biotechnol Biochem, Jan 2016
Exogenous ABA resulted in the enhancement of glutamate decarboxylase (GAD) and diamine oxidase (DAO) activity as well as GABA content in cotyledon and shoot.
[Effects of Couplet Medicines (Astragalus Membranaceus and Jiaozhen) on Intestinal Barrier in Postoperative Colorectal Cancer Patients].
Jiang et al., In Zhongguo Zhong Xi Yi Jie He Za Zhi, Nov 2015
Levels of blood D-lactic acid, diamine oxidase (DAO), urinary lactulose/mannitol ratio (L/M), ET, TNF-alpha, and postoperative recovery time of bowel sound were observed before surgery and after surgery.
Histamine, histamine intoxication and intolerance.
Plevkova et al., Martin, Slovakia. In Allergol Immunopathol (madr), Sep 2015
Correct diagnosis of HIT followed by therapy based on histamine-free diet and supplementation of diamine oxidase can improve patient's quality of life.
Relationship of epigenetic and Dao-di herbs.
Huang et al., In Zhongguo Zhong Yao Za Zhi, Jul 2015
Dao-di Herbs is specificity and locality, and its unique phenotypic features is closely related to the growth and development of medicinal plants.
Inhibition and oxygen activation in copper amine oxidases.
Dooley et al., Bozeman, United States. In Acc Chem Res, Jun 2015
This is vital given the existence of human diamine oxidase and vascular adhesion protein-1, which have distinct amine substrate preferences and are associated with different metabolic processes.
Physiological Roles of Hydrogen Sulfide and Polysulfides.
Kimura, Kodaira, Japan. In Handb Exp Pharmacol, 2014
Recently, a novel pathway for the production of H2S from D-cysteine was identified, involving D-amino acid oxidase (DAO) together with 3MST.
Bacterial d-amino acid oxidases: Recent findings and future perspectives.
Kera et al., Nagaoka, Japan. In Bioengineered, 2014
D-Amino acid oxidase (DAO) is a flavin enzyme that catalyzes the oxidative deamination of d-amino acids.
Protective role of D-amino acid oxidase against Staphylococcus aureus infection.
Maeda et al., Kumamoto, Japan. In Infect Immun, 2012
results suggest that DAO, together with myeloperoxidase, may play an important role in antibacterial systems in mammals
Src-mediated phosphorylation of mammalian Abp1 (DBNL) regulates podosome rosette formation in transformed fibroblasts.
Huttenlocher et al., Madison, United States. In J Cell Sci, 2012
study identifies a role for the actin binding protein mAbp1 in the formation of podosome rosettes and regulation of invasive cell migration
D-amino acid oxidase controls motoneuron degeneration through D-serine.
Aiso et al., Tokyo, Japan. In Proc Natl Acad Sci U S A, 2012
DAO has a pivotal role in motoneuron degeneration through D-serine regulation, with inactivity of DAO being a common feature between the mSOD1 ALS mouse model and mutant DAO-associated familial ALS.
Genetic vulnerability to psychosis and cortical function: epistatic effects between DAAO and G72.
McGuire et al., London, United Kingdom. In Curr Pharm Des, 2011
A significant 3 way interaction between G72, DAAO and diagnosis is detected in the right middle temporal gyrus (after family-wise error correction), accounting for 8.5% of the individual variance in activation.
Plasma diamine oxidase activity is a useful biomarker for evaluating gastrointestinal tract toxicities during chemotherapy with oral fluorouracil anti-cancer drugs in patients with gastric cancer.
Hanazaki et al., Kōchi, Japan. In Oncology, 2011
Low diamine oxidase activity is associated with gastrointestinal tract toxicities during chemotherapy with oral fluorouracil anti-cancer drugs in patients with gastric cancer.(
A conditional marker gene allowing both positive and negative selection in plants.
Näsholm et al., In Nat Biotechnol, 2004
We present a marker gene, dao1, encoding D-amino acid oxidase (DAAO, EC that can be used for either positive or negative selection, depending on the substrate.
Environmentally safe production of 7-aminodeacetoxycephalosporanic acid (7-ADCA) using recombinant strains of Acremonium chrysogenum.
Barredo et al., León, Spain. In Nat Biotechnol, 2000
DAOC deacylation is carried out by two final enzymatic bioconversions catalyzed by D-amino acid oxidase (DAO) and glutaryl acylase (GLA) yielding 7-ADCA.
D-valine as a selective agent for normal human and rodent epithelial cells in culture.
Migeon et al., In Cell, 1975
In this medium, D-valine is substituted for L-valine; and only those cells containing D-amino acid oxidase can convert the D-amino acid into its essential L-enantiomer.
REED, In Science, 1965
The relative rate of oxidation of putrescine to Delta(1)-pyrroline compared to that of tryptamine by these extracts and the inhibition of both reactions by beta-hydroxyethylhydrazine suggest that diamine oxidase is inhibited.
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