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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Diacylglycerol kinase, iota

This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on DGKiota
SNP variations in the 7q33 region containing DGKI are associated with dyslexia in the Finnish and German populations.
Peyrard-Janvid et al., Huddinge, Sweden. In Behav Genet, 2011
Here, we report results from a fine-mapping approach involving linkage and association analysis in Finnish and German dyslexic cohorts. We restrict a candidate region to 0.3 Mb on chromosome 7q33.
Cloning and characterization of diacylglycerol kinase iota splice variants in rat brain.
Goto et al., Yamagata, Japan. In J Biol Chem, 2004
novel splice variants, which contain either insertion 1 (71 bp) or insertion 2 (19 bp) or both in the carboxyl-terminal portion
Differential expression of diacylglycerol kinase iota and L18A mRNAs in the brains of alcohol-preferring AA and alcohol-avoiding ANA rats.
Heilig et al., Huddinge, Sweden. In Mol Psychiatry, 2001
Diacylglycerol kinase iota is exclusively found in the brain and is expressed in a distinct regional pattern. Differential expression of splice variants in the cortex of alcohol accepting (AA) and alcohol non-accepting (ANA) rat lines.
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