Diagnostic performance of the "MESACUP anti-Skin profile TEST".
Budapest, Hungary. In Eur J Dermatol, Feb 2016
UNASSIGNED: The "MESACUP anti-Skin profile TEST" test is a new, commercially available ELISA kit to detect circulating IgG autoantibodies against desmoglein 1, desmoglein 3, BP180, BP230, and type VII collagen, both simultaneously and more rapidly than previous assays.
Pemphigus in the Arab world.
Cairo, Egypt. In J Dermatol, 2015
The presence of anti-desmoglein 1 antibodies in the sera of normal Tunisians and the presence of anti-desmoglein 3 in normal Egyptians' sera suggested that environmental factors played a role in the disease pathogenesis in those areas.
Rituximab therapy improves recalcitrant Pemphigus vulgaris.
Tehrān, Iran. In Excli J, 2014
Pemphigus disease activity index (PDAI), anti-desmoglein 1 and anti-desmoglein 3 antibody titers, and percent of CD20 positive cells were measured at baseline, 10 ± 1, and 22 ± 2 weeks after rituximab therapy.
Pemphigus herpetiformis: from first description until now.
Lübeck, Germany. In J Am Acad Dermatol, 2014
The target autoantigen is usually desmoglein 1 (or less frequently desmoglein 3), although recently it has become increasingly obvious that patients with pemphigus herpetiformis also demonstrate autoantibodies against desmocollin.
Desmoglein as a target in skin disease and beyond.
Tokyo, Japan. In J Invest Dermatol, 2012
The identification of desmogleins 1 and 3, desmosomal adhesion glycoproteins, as targets in pemphigus, a fatal autoimmune blistering disease of the skin and mucous membranes, provided the first link between desmosomes, desmogleins, and human diseases.