Signaling in the plant cytosol: cysteine or sulfide?
Sevilla, Spain. In Amino Acids, Oct 2015
Another member of the OASTL family is DES1, a novel L-cysteine desulfhydrase that catalyzes the desulfuration of Cys to produce sulfide, thus acting in a manner opposite to that of OAS-A1.
Allosteric activation of DegS, a stress sensor PDZ protease.
Cambridge, United States. In Cell, 2007
When protein folding is compromised in the periplasm of E. coli, the C termini of outer-membrane proteins (OMPs) bind to the PDZ domains of the trimeric DegS protease and activate cleavage of RseA, a transmembrane transcriptional regulator.
A PDZ switch for a cellular stress response.
Heidelberg, Germany. In Cell, 2004
The accumulation of misfolded porins in the periplasm of bacteria triggers a proteolytic cascade, initiated by activation of DegS, a member of the family of HtrA proteases.