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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Opioid receptor, delta 1

delta-opioid receptor, OprD, OPRD1
Top mentioned proteins: HAD, Enkephalin, CAN, V1a, ACID
Papers on delta-opioid receptor
A two-centre evaluation of RAPIDEC® CARBA NP for carbapenemase detection in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter spp.
New
Woodford et al., Stockholm, Sweden. In J Antimicrob Chemother, Feb 2016
The exceptions were one Klebsiella oxytoca, which was later found to produce GES-5 carbapenemase, one Pseudomonas aeruginosa with OprD loss and increased efflux, and one Enterobacter cloacae with impermeability.
Tumor Targeting and Pharmacokinetics of a Near-Infrared Fluorescent-Labeled δ-Opioid Receptor Antagonist Agent, Dmt-Tic-Cy5.
New
Morse et al., Tucson, United States. In Mol Pharm, Feb 2016
Herein, we investigated the pharmacokinetics (PK) and cellular uptake of Dmt-Tic-Cy5, a delta-opioid receptor (δOR) antagonist-fluorescent dye conjugate, as a tumor-targeting molecular imaging agent.
Searching for evidence of genetic mediation of opioid withdrawal by opioid receptor gene polymorphisms.
New
Comer et al., New York City, United States. In Am J Addict, Jan 2016
The total withdrawal severity score (based on the COWS) from this procedure was correlated with genotype information for variants of OPRM1 (rs1799971; rs6848893), OPRD1 (rs10753331; rs2234918; rs581111; rs678849; rs1042114), and OPRK1 (rs6473797; rs963549).
Emerging treatments in neurogastroenterology: eluxadoline - a new therapeutic option for diarrhea-predominant IBS.
Review
New
Lacy, United States. In Neurogastroenterol Motil, Jan 2016
This unmet need led to the development of eluxadoline, a mu-opioid receptor agonist/delta-opioid receptor antagonist/kappa-receptor agonist.
Mutational inactivation of OprD in carbapenem-resistant Pseudomonas aeruginosa isolates from Korean hospitals.
New
Lee et al., Taegu, South Korea. In J Microbiol, Jan 2016
Mutations in the oprD gene and a related decrease in gene expression were found in 21 and 5 isolates, respectively.
Antagonism of the met5-enkephalin-opioid growth factor receptor-signaling axis promotes MSC to differentiate into osteoblasts.
New
Margulies et al., In J Orthop Res, Jan 2016
The opioid growth factor receptor (OGFR) is a non-canonical opioid receptor that binds naloxone with high affinity while the native opioid growth factor, met5-enkephalin (met5), binds both the OGFR and the canonical delta opioid receptor (OPRD).
The role of opioidergic genes in the treatment outcome of drug addiction pharmacotherapy: A systematic review.
Review
Nielsen et al., Houston, United States. In Am J Addict, 2015
RESULTS AND CONCLUSIONS: The genetic variability of μ-, δ- and κ-opioid receptors genes OPRM1, OPRD1, and OPRK1 modulates the efficacy of opioid antagonist treatments such as naltrexone and methadone, as well as the cocaine vaccine.
Profile of ceftolozane/tazobactam and its potential in the treatment of complicated intra-abdominal infections.
Review
Skalweit, Cleveland, United States. In Drug Des Devel Ther, 2014
Ceftolozane is a uniquely potent antipseudomonal cephalosporin because of its high affinity for the penicillin-binding proteins of Pseudomonas aeruginosa, its low affinity for the intrinsic Class C β-lactamases of P. aeruginosa, its ability to enter P. aeruginosa through the outer membrane without the utilization of OprD protein, and the fact that it is not a substrate of the often upregulated MexAB/OprM efflux system of P. aeruginosa.
A review of the role of genetic testing in pain medicine.
Review
Faynboym et al., Indianapolis, United States. In Pain Physician, 2014
METHODS: This article discusses the specific pain implications of genetic variations in CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A7, OPRM1, OPRK1, OPRD1, COMT, GABA, UGT, MC1R, GCH1, ABCB1, P-glycoprotein, 5HTR1A, 5HTR2A, MTHFR, CACNA2D2, and 5-HTTLPR.
Optimization and characterization of an opioid kappa receptor (OPRK1) antagonist
Review
Rosen et al., Bethesda, United States. In Unknown Journal, 2013
The opioid receptors are a subfamily of the family A G protein-coupled opioid receptor superfamily and consist of mu (OPRM1), delta (OPRD1), and kappa (OPRK1), all of which activate inhibitory G proteins.
Cortical opioid markers in schizophrenia and across postnatal development.
GeneRIF
Lewis et al., Pittsburgh, United States. In Cereb Cortex, 2012
no differences in DOR mRNA levels were seen in schizophrenia.
ßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands.
GeneRIF
Allouche et al., Caen, France. In Cell Signal, 2012
ssarrestin1 is exclusively involved in human delta-opioid receptor desensitization
Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization.
GeneRIF
Petäjä-Repo et al., Oulu, Finland. In J Biol Chem, 2012
Cys-27 variant of human delta-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization.
Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons.
GeneRIF
Devi et al., New York City, United States. In Plos One, 2011
between CBR and delta opioid receptor
Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking.
GeneRIF
Hiltunen et al., Kuopio, Finland. In Mol Cell Biol, 2011
data suggest that an increased constitutive internalization and/or concurrent signaling of the delta-opioid receptor-Cys27 variant affects APP processing through altered endocytic trafficking of APP
Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.
Impact
von Zastrow et al., Pittsburgh, United States. In Cell, 2010
Here, in live cells, we visualize the sorting of a prototypical sequence-dependent recycling receptor, the beta-2 adrenergic receptor, from bulk recycling proteins and the degrading delta-opioid receptor.
Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation.
Impact
Pei et al., Shanghai, China. In Nat Med, 2006
Similar effects were observed after activation of delta-opioid receptor.
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription.
Impact
Ma et al., Shanghai, China. In Cell, 2006
Here, we show that stimulation of delta-opioid receptor, a member of the GPCR family, induces nuclear translocation of beta-arrestin 1 (betaarr1), which was previously known as a cytosolic regulator and scaffold of GPCR signaling.
A neuropeptide courier for delta-opioid receptors?
Impact
Basbaum et al., San Francisco, United States. In Cell, 2005
The delta-opioid receptor and the precursor protein of a neuropeptide, substance P, are colocalized in the large dense-core vesicles of pain-sensing neurons.
Kappa- and delta-opioid receptor agonists differentially inhibit striatal dopamine and acetylcholine release.
Impact
Frankhuyzen et al., In Nature, 1984
At least three different families of endogenous opioid peptides, the enkephalins, endorphins and dynorphins, are present in the mammalian central nervous system (CNS).
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