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Secretion regulating guanine nucleotide exchange factor

DelGEF, deafness locus associated putative guanine nucleotide exchange factor
Top mentioned proteins: RAN, Sec5, ACID, CAN, RCC1
Papers on DelGEF
Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
Shi et al., Hefei, China. In Biochemistry, 2005
Furthermore, Kti11p/Dph3 was found to physically interact with core-Elongator, ribosomal proteins, eEF-2, two other proteins required for diphthamide modification on eEF-2, and DelGEF.
Characterisation of an evolutionary conserved protein interacting with the putative guanine nucleotide exchange factor DelGEF and modulating secretion.
Ponstingl et al., Heidelberg, Germany. In Exp Cell Res, 2004
A human cDNA library was screened for proteins interacting with the deafness locus putative guanine nucleotide exchange factor (DelGEF) using a yeast two-hybrid system.
DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.
GeneRIF
Ponstingl et al., Heidelberg, Germany. In Febs Lett, 2003
DelGEF binds to the human homologue of Sec5 and modulates secretion.
DelGEF, an RCC1-related protein encoded by a gene on chromosome 11p14 critical for two forms of hereditary deafness.
Ponstingl et al., Heidelberg, Germany. In Febs Lett, 1999
We have cloned a human cDNA, DELGEF (deafness locus associated putative guanine nucleotide exchange factor), derived from a 225 kb genomic sequence of chromosome 11p14, critical for the Usher 1C syndrome and for DFNB18, a locus for non-syndromic sensorineural deafness.
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