Defensin-based anti-infective strategies.
Bonn, Germany. In Int J Med Microbiol, 2014
Cationic and amphiphilic peptides are widely distributed in eukaryotic organisms and constitute a first line of host defense against invading pathogens.
IL-22 increases the innate immunity of tissues.
Berlin, Germany. In Immunity, 2004
In these cells, IL-22 activated STAT3 and directly and transcriptionally increased the expression of beta-Defensin 2 and beta-Defensin 3. High levels of IL-22 were associated with strongly upregulated beta-Defensin expression in skin from patients with T cell-mediated dermatoses.