SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival.
Helsinki, Finland. In Oncotarget, Dec 2015
Based on in silico functional analyses and literature, we speculate that the rs5996080 and rs7973914 loci may affect the BAFFR and TNFR1/TNFR3 receptors and breast cancer survival, possibly by disturbing both the canonical and non-canonical NF-κB pathways or their dynamics, whereas, rs17243893-rs57890595 interaction on survival may be mediated through TRAF2-TRAIL-R4 interplay.
Inhibition of apoptosis in periodontitis.
Adelaide, Australia. In J Dent Res, 2010
Higher levels of TRAIL and the TRAIL decoy receptor, TRAIL R4, were expressed by leukocytes in inflamed human periodontal tissues.
Trail and kidney disease.
Madrid, Spain. In Front Biosci, 2008
TRAIL may modulate cell survival and proliferation through interaction with two different receptors, TRAIL-R1 and TRAIL-R2, and the actions of TRAIL are regulated by three decoy receptors, TRAIL-R3, TRAIL-R4 and osteoprotegerin.