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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

NSL1, MIND kinetochore complex component, homolog

DC8
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, ACID, CD16, V1a, DC13
Papers on DC8
Diverse functional outcomes of Plasmodium falciparum ligation of EPCR: potential implications for malarial pathogenesis.
New
Ho et al., Calgary, Canada. In Cell Microbiol, Dec 2015
In this study, we examined the adhesion of DC8- and DC13-expressing parasite lines to endothelial cells from different microvasculature, and the consequences of EPCR engagement on endothelial cell function.
Controlled and Targeted Drug Delivery by a UV-responsive Liposome for Overcoming Chemo-resistance in Non-Hodgkin Lymphoma.
New
Zhang et al., Shanghai, China. In Chem Biol Drug Des, Oct 2015
In this study, we successfully fabricated a CD20-targeting immuno-liposome based on 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine (DC-8,9PC), which can form intermolecular cross-linking through the diacetylenic group by ultraviolet irradiation.
Statistical Analysis of Electrical Properties of Octanemonothiol versus Octanedithol in PEDOT:PSS-Electrode Molecular Junctions.
New
Lee et al., In J Nanosci Nanotechnol, Aug 2015
UNLABELLED: We fabricated a large number of octanemonothiol (C8) and octanedithol (DC8) molecular electronic devices with PEDOT: PSS (3,4-ethylenedioxythiophene) interlayer and performed a statistical analysis on the electronic properties of these devices.
Airborne measurements of organosulfates over the continental U.S.
New
Diskin et al., Boulder, United States. In J Geophys Res Atmos, May 2015
In this study, we report two organosulfates, an isoprene-derived isoprene epoxydiols (IEPOX) (2,3-epoxy-2-methyl-1,4-butanediol) sulfate and a glycolic acid (GA) sulfate, measured using the NOAA Particle Analysis Laser Mass Spectrometer (PALMS) on board the NASA DC8 aircraft over the continental U.S. during the Deep Convective Clouds and Chemistry Experiment (DC3) and the Studies of Emissions and Atmospheric Composition, Clouds, and Climate Coupling by Regional Surveys (SEAC4RS).
Mother-of-pearl cloud particle size and composition from aircraft-based photography of coloration and lidar measurements.
New
Yang et al., In Appl Opt, Mar 2015
During a Stratospheric Aerosol and Gas (SAGE)-III Ozone Loss and Validation Experiment (SOLVE)-II science flight on 4 February 2003, a mother-of-pearl cloud over Iceland was underflown by the NASA DC-8 and measured with the lidars onboard.
Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding.
Gamain et al., Paris, France. In Malar J, 2014
A restricted sub-set of var genes encoding for PfEMP1s possessing the domain cassettes DC8 and DC13 were found to bind to the endothelial protein C receptor (EPCR).
Differential Plasmodium falciparum surface antigen expression among children with Malarial Retinopathy.
Bull et al., Kilifi, Kenya. In Sci Rep, 2014
We found no evidence for an elevation of DC8 or DC13 PfEMP1 expression in children with retinopathy.
Cytoadherence phenotype of Plasmodium falciparum-infected erythrocytes is associated with specific pfemp-1 expression in parasites from children with cerebral malaria.
Tahar et al., Paris, France. In Malar J, 2013
METHODS: Cytoadherence phenotypes of IEs to CD36, ICAM-1, CSPG and the transcription patterns of A, B, var2csa, var3, var gene groups and domain cassettes DC8 and DC13 were assessed in parasites from children with CM and uncomplicated malaria (UM) to determine if cytoadherence is related to a specific transcription profile of pfemp-1 variants.
Expression and diagnostic values of calretinin and CK5/6 in cholangiocarcinoma.
Zhang et al., Philadelphia, United States. In Exp Hematol Oncol, 2013
The immunohistochemical study of Calretinin (DC8), WT1 (6F-H2), Lymphatic Endothelial Marker (D2-40), CK5/6 (D5/16 B4) and CK19 (b170) was done on formalin fixed paraffin embedded sections for 2-3 blocks of each case.
Potentiating antilymphoma efficacy of chemotherapy using a liposome for integration of CD20 targeting, ultra-violet irradiation polymerizing, and controlled drug delivery.
Deng et al., Shanghai, China. In Nanoscale Res Lett, 2013
In this study, we finely fabricated a rituximab Fab fragment-decorated liposome based on 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine (DC8,9PC), which can form intermolecular cross-linking through the diacetylenic group by ultra-violet (UV) irradiation.
Severe malaria is associated with parasite binding to endothelial protein C receptor.
Impact
Theander et al., Copenhagen, Denmark. In Nature, 2013
Here we identify endothelial protein C receptor (EPCR), which mediates the cytoprotective effects of activated protein C, as the endothelial receptor for DC8 and DC13 PfEMP1.
Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes.
GeneRIF
Yanagida et al., Kyoto, Japan. In J Cell Biol, 2010
The hMis14, which contains a tripartite-binding domain for HP1 and two other kinetochore proteins, hMis13 and blinkin, is a cornerstone for the assembly of the inner centromere and kinetochore.
Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS.
GeneRIF
Ostvold et al., Oslo, Norway. In Biochim Biophys Acta, 2007
The NLS1 signal is highly conserved between the species investigated, and fits the description of being a classical bipartitie NSL.
Human 6-sulfo LacNAc-expressing dendritic cells are principal producers of early interleukin-12 and are controlled by erythrocytes.
Impact
Rieber et al., Dresden, Germany. In Immunity, 2006
These so-called slanDC are characterized by the 6-sulfo LacNAc modification of PSGL-1, which is identified by the mAb M-DC8.
A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.
Impact
Yanagida et al., Kyoto, Japan. In Nat Cell Biol, 2004
Four other human proteins of unknown function (c20orf172, DC8, PMF1 and KIAA1570) correspond to yeast Mis12-Mtw1 complex components and are shown to be required for chromosome segregation in HeLa cells using RNA interference (RNAi).
6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells.
Impact
Rieber et al., Dresden, Germany. In Immunity, 2002
The monoclonal antibody M-DC8 defines a major subset of human blood dendritic cells (DCs).
Survival at high altitudes: wheel-well passengers.
Review
Sahiar et al., Oklahoma City, United States. In Aviat Space Environ Med, 1996
Three Douglas DC-8 and four Boeing 707 aircraft, plus a Caravelle, an unknown jet, and a piston airliner were involved.
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