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D site albumin promoter binding protein

Dbp, D site-binding protein, D site albumin promoter binding protein
transcriptional activator; binds to the D site of the albumin promoter [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CLOCK, Tic, period 2, CRY1, Serum albumin
Papers on Dbp
RBP4 functions as a hepatokine in the regulation of glucose metabolism by the circadian clock in mice.
New
Liu et al., Shanghai, China. In Diabetologia, Feb 2016
Aryl hydrocarbon receptor nuclear translocator-like (also known as BMAL1) and its target D site-binding protein (DBP) are both pivotal transcription factors of the circadian core clock.
Alterations of hepatic metabolism in chronic kidney disease via D-box binding protein aggravate the renal dysfunction.
New
Ohdo et al., Japan. In J Biol Chem, Feb 2016
In addition, D-box binding protein (DBP), which controls the expression of several CYP genes, was significantly decreased in these mice.
New transcription factors involved with postnatal ventral prostate gland development in male Wistar rats during the first week.
New
Carvalho et al., Campinas, Brazil. In Life Sci, Jan 2016
KEY FINDINGS: 16 TFs were studied and we found an increased expression of Eya2, Lhrh and Znf142, invariable levels of Znf703 and Dbp, and decreased expression of 11 others at postnatal development day 3 and 6 as compared to day zero.
Mitomycin C modulates the circadian oscillation of clock gene period 2 expression through attenuating the glucocorticoid signaling in mouse fibroblasts.
New
Kubota et al., Ōita, Japan. In Biochem Biophys Res Commun, Dec 2015
Following MMC treatment, Bmal1 mRNA levels was significantly decreased, whereas Dbp, Per1, and Rev-erbα mRNA levels were significantly increased in the mouse fibroblast cell line NIH3T3 cells.
Short-term circadian disruption impairs bile acid and lipid homeostasis in mice.
New
Chiang et al., United States. In Cell Mol Gastroenterol Hepatol, Dec 2015
ChIP assay revealed HNF4α and Dbp occupancies were suppressed at the Cyp7a1 promoter in sleep-disrupted mice.
Pgc-1α and Nr4a1 Are Target Genes of Circadian Melatonin and Dopamine Release in Murine Retina.
New
Spessert et al., Mainz, Germany. In Invest Ophthalmol Vis Sci, Sep 2015
The aim of the present study was to screen transcriptional regulators important for retinal physiology and/or pathology (Dbp, Egr-1, Fos, Nr1d1, Nr2e3, Nr4a1, Pgc-1α, Rorβ) for circadian regulation and dependence on melatonin signaling/MT1 receptors or dopamine signaling/D4 receptors.
Transcriptome-wide Changes in Coral Gene Expression at Noon and Midnight Under Field Conditions.
New
Palumbi et al., Pacific Grove, United States. In Biol Bull, Jun 2015
The largest changes were in a set of transcription factors strongly associated with day-night gene regulation in other animals, including cryptochromes, thyrotroph embryonic factor, and D site-binding protein.
Potential Biomarkers for Radiation-Induced Renal Toxicity following 177Lu-Octreotate Administration in Mice.
Forssell-Aronsson et al., Göteborg, Sweden. In Plos One, 2014
The Cdkn1a, C3, Dbp, Lcn2, and Per2 genes displayed a distinct dose-dependent regulation, with increased expression level with increasing absorbed dose.
Twist1 Is a TNF-Inducible Inhibitor of Clock Mediated Activation of Period Genes.
Fontana et al., Zürich, Switzerland. In Plos One, 2014
Tumor necrosis factor (TNF) and Interleukin (IL)-1β inhibit the expression of clock genes including Period (Per) genes and the PAR-bZip clock-controlled gene D-site albumin promoter-binding protein (Dbp).
Bacterial bile salt hydrolase in host metabolism: Potential for influencing gastrointestinal microbe-host crosstalk.
Review
Gahan et al., Cork, Ireland. In Gut Microbes, 2013
Key mediators of cholesterol homeostasis (Abcg5/8), gut homeostasis (RegIIIγ) and circadian rhythm (Dbp) were influenced by elevated BSH in our study.
Loss of coiled-coil domain containing 80 negatively modulates glucose homeostasis in diet-induced obese mice.
GeneRIF
Gimeno et al., Boston, United States. In Endocrinology, 2012
In Ccdc80(-/-) mice, expression of the core clock member Arntl/Bmal1 was reduced whereas that of the oscillating transcription factors Dbp and Tef was increased in all tissues examined.
Cellular DBP and E4BP4 proteins are critical for determining the period length of the circadian oscillator.
GeneRIF
Hashimoto et al., Tsukuba, Japan. In Febs Lett, 2011
Data show that knockdown of DBP, D-box positive regulator, led to a short-period phenotype, and overexpression of DBP produced a long-period rhythm, while knockdown and overexpression of E4BP4, D-box negative regulator, had the opposite effect of DBP.
Circadian transcriptional factor DBP regulates expression of Kiss1 in the anteroventral periventricular nucleus.
GeneRIF
Adachi et al., Saitama, Japan. In Mol Cell Endocrinol, 2011
Dbp and estrogen regulate the expression of Kiss1 in the anteroventral periventricular nucleus
Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight, and type 2 diabetic.
GeneRIF
Johnston et al., United Kingdom. In Diabetes, 2011
Lean individuals exhibited significant (P < 0.05) temporal changes of core clock (PER1, PER2, PER3, CRY2, BMAL1, and DBP) and metabolic (REVERBalpha, RIP140, and PGC1alpha) genes.
Impairment of peripheral circadian clocks precedes metabolic abnormalities in ob/ob mice.
GeneRIF
Fujimura et al., Tochigi, Japan. In Endocrinology, 2011
The daily mRNA expression profiles of the clock and clock-controlled genes Clock, Bmal1, Cry1, Per1, Per2, and Dbp were substantially dampened in the liver and adipose tissue of 10-wk-old ob/ob mice.
[Assessment by logistic model of hemodynamic changes during general anesthesia].
Review
Hanaoka et al., Wilmington, United States. In Masui, 2008
The time courses of systolic (sBP) and diastolic blood pressure (dBP) and heart rate (HR) are expressed as sigmoidal curve.
Sickness behaviour pushed too far--the basis of the syndrome seen in severe protozoal, bacterial and viral diseases and post-trauma.
Review
Alleva et al., Canberra, Australia. In Malar J, 2007
It is thus proposed that the pattern of pathology that comprises much of the systemic inflammatory syndrome occurs when one of the usually advantageous roles of pro-inflammatory cytokines--generating sickness behaviour by moderately repressing genes (Dbp, Tef, Hlf, Per1, Per2 and Per3, and the nuclear receptor Rev-erbalpha) that control circadian rhythm--becomes excessive.
Evidence-based management for preeclampsia.
Review
Magee et al., Vancouver, Canada. In Front Biosci, 2006
(4) Initiate antihypertensive drug treatment immediately if sBP >160 mmHg or dBP more than 110 mmHg, or if sBP 140-159 mmHg and/or dBP 85-109 mmHg (prepregnancy renal disease or diabetes).
Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions.
Impact
GeneRIF
Schibler et al., Genève, Switzerland. In Nat Genet, 2006
Dbp transcription cycle is paralleled by binding of BMAL1 and CLOCK to multiple extra- and intragenic E boxes.
Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation.
Review
Impact
Borlak et al., Hannover, Germany. In Pharmacol Rev, 2004
Now we summarize the role of basic region/leucine zipper protein family members and particularly the albumin D site-binding protein (DBP) and the CAAT/enhancer-binding proteins (C/EBPs) for their importance in liver-specific gene expression and their role in liver function and development.
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