Common genetic variants on 1p13.2 associate with risk of autism.
Changsha, China. In Mol Psychiatry, 2014
× 10(-8)), non-synonymous rs6537835 (P=3.26 × 10(-8)) and rs1877455 (P=8.70 × 10(-8)), and related haplotypes, AMPD1-NRAS-CSDE1, TRIM33 and TRIM33-BCAS2, associated with autism; all were mapped to a previously reported linkage region (1p13.2) with autism.
Crucial role for endoplasmic reticulum stress during megakaryocyte maturation.
Le Kremlin-Bicêtre, France. In Arterioscler Thromb Vasc Biol, 2013
APPROACH AND RESULTS: Investigation of ER stress and maturation markers in different models of human thrombopoiesis (CHRF, DAMI, MEG-01 cell lines, and hematopoietic stem cells: CD34(+)) as well as in immature pathological platelets clearly indicated that ER stress occurs transiently during thrombopoiesis.