Ghosh et al., Calcutta, India. In Fems Yeast Res, 2013
Furthermore, in the absence of Iml3p, the two-hybrid interaction between Ctf19p (a member of the Ctf19 complex) and Dam1p (a member of the outer kinetochore DASH complex) was disrupted and the localization of Dam1p at the kinetochore was also compromised.
Basrai et al., Bethesda, United States. In Mol Biol Cell, 2013
Consistent with these results, we observe that a phosphomimetic cse4-4SD mutant suppresses the temperature-sensitive growth of ipl1-2 and Ipl1 substrate mutants dam1 spc34 and ndc80, which are defective for chromosome biorientation.
Dent et al., Anderson, United States. In Cell, 2011
Paf1 complex and Rad6-Bre1-mediated ubiquitination of H2BK123 are required for Dam1 methylation at the kinetochore and therefore inhibit Ipl1-mediated phosphorylation, revealing unexpected functions for these proteins in mitosis.
Berman et al., Minneapolis, United States. In Curr Biol, 2011
The Dam1 complex is required for viability because its function as a processivity factor for kinetochore-microtubule binding is more critical when chromosome segregation is dependent upon a single kinetochore-microtubule.
Barnes et al., Berkeley, United States. In Cell, 2002
Our systematic mutational analysis of the Ipl1p phosphorylation sites demonstrated that the essential microtubule binding protein Dam1p is a key Ipl1p target for regulating kinetochore-microtubule attachments in vivo.