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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Caspase recruitment domain family, member 8

Dakar, Cardinal
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010] (from NCBI)
Top mentioned proteins: AGE, HAD, OUT, CAN, MEN
Papers using Dakar antibodies
Three cases of PICU sedation with isoflurane delivered by the ‘AnaConDa’
Sirtl Clemens et al., In Journal of Clinical Monitoring and Computing, 2004
... The syringe pump (Ivac®, Cardinal Health—Alaris Products, Dublin, Ohio, USA) adjusted for Becton Dickinson Plastipak syringes with a high ...
Papers on Dakar
Dynamics of Vector-Host Interactions in Avian Communities in Four Eastern Equine Encephalitis Virus Foci in the Northeastern U.S.
Andreadis et al., Corvallis, United States. In Plos Negl Trop Dis, Jan 2016
These included: American Robin, Tufted Titmouse, Common Grackle, Wood Thrush, Chipping Sparrow, Black-capped Chickadee, Northern Cardinal, and Warbling Vireo.
Ghrelin and gastroparesis as early predictors of clinical outcomes in acute pancreatitis.
Petrov et al., Auckland, New Zealand. In Pancreatology, Jan 2016
The aim of the present study was to investigate the predictive value of the Gastroparesis Cardinal Symptom Index and serum ghrelin in the development of clinically meaningful outcomes in patients with acute pancreatitis.
Regression of Atherosclerosis: The Journey From the Liver to the Plaque and Back.
Fisher, New York City, United States. In Arterioscler Thromb Vasc Biol, Jan 2016
UNASSIGNED: Cardinal events in atherogenesis are the retention of apolipoprotein B-containing lipoproteins in the arterial wall and the reaction of macrophages to these particles.
A Regional Climate Mode Discovered in the North Atlantic: Dakar Niño/Niña.
Yamagata et al., Yokohama, Japan. In Sci Rep, Dec 2015
The coupled warm (cold) event is named Dakar Niño (Niña).
Cost of hospitalization by the Activity Based Costing method in the neonatal department of Principal Hospital of Dakar.
Agbétra et al., Lomé, Togo. In Med Sante Trop, Dec 2015
UNASSIGNED: To determine the cost of hospitalization per day in the neonatal department of Principal Hospital of Dakar.
Recent advances in biomarkers for Parkinson's disease focusing on biochemicals, omics and neuroimaging.
Pu et al., In Clin Chem Lab Med, Oct 2015
Cardinal symptoms including tremors, muscle rigidity, drooping posture, drooping, walking difficulty, and autonomic symptoms appear when a significant number of nigrostriatal dopaminergic neurons have already been destroyed.
Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic.
Sall et al., Paris, France. In Nature, Sep 2015
In March 2014, when the first cases were detected in Conakry, the Institut Pasteur of Dakar, Senegal, deployed a mobile laboratory in Donka hospital to provide diagnostic services to the greater Conakry urban area and other regions of Guinea.
IVUmed: a nonprofit model for surgical training in low-resource countries.
deVries et al., Dakar, Senegal. In Ann Glob Health, Mar 2015
Program partners, such as Hopital General de Grand Yoff in Dakar, Senegal, have advanced from little urological subspecialty availability to having the capacity to treat a wide range of conditions while also teaching surgeons from Senegal and neighboring countries.
Vasculopathy and pulmonary hypertension in sickle cell disease.
Gladwin et al., Pittsburgh, United States. In Am J Physiol Lung Cell Mol Physiol, Mar 2015
Cardinal features include severe painful crises and episodic acute lung injury, called acute chest syndrome.
Therapeutic applications of ghrelin agonists in the treatment of gastroparesis.
Wo et al., Indianapolis, United States. In Curr Gastroenterol Rep, Feb 2015
RM-131 reduced total Gastroparesis Cardinal Symptom Index-Daily Diary (GCSI-DD) and composite scores among type 1 diabetics.
MALDI-TOF Mass Spectrometry: A Powerful Tool for Clinical Microbiology at Hôpital Principal de Dakar, Senegal (West Africa).
Fenollar et al., Dakar, Senegal. In Plos One, 2014
To evaluate the utility of MALDI-TOF MS in tropical Africa in collaboration with local teams, we installed an apparatus in the Hôpital Principal de Dakar (Senegal), performed routine identification of isolates, and confirmed or completed their identification in France.
Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial.
Pasricha et al., Baltimore, United States. In Jama, 2014
Inclusion criteria included delayed gastric emptying and moderate to severe symptom scores using the Gastroparesis Cardinal Symptom Index (GCSI).
Association study of CARD8 (p.C10X) and NLRP3 (p.Q705K) variants with rheumatoid arthritis in French and Tunisian populations.
Maalej et al., Sfax, Tunisia. In Int J Immunogenet, 2012
Variations in the CARD8 and NLRP3 genes are not associated with rheumatoid arthritis in the French as well general Tunisian population.
Polymorphisms in inflammasome' genes and susceptibility to HIV-1 infection.
Duarte et al., São Paulo, Brazil. In J Acquir Immune Defic Syndr, 2012
Twelve single nucleotide polymorphisms within NLRP1, NLRP3, NLRC4, CARD8, CASP1, and IL1B genes were analyzed in 150 HIV-1-infected Brazilian subjects.
Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms.
Jones et al., Dunedin, New Zealand. In Atherosclerosis, 2011
analysis of interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms
CASP8 -652 6N del and CASP8 IVS12-19G>A gene polymorphisms and susceptibility/prognosis of ESCC: a case control study in northern Indian population.
Mittal et al., Lucknow, India. In J Surg Oncol, 2011
Caspase8 polymorphism IVS12-19 G>A but not CASP8 -652 6N del polymorphism may modulate risk of esophageal squamous cell carcinoma and its survival outcome in northern Indian population.
CARD8 and NLRP1 undergo autoproteolytic processing through a ZU5-like domain.
Reed et al., Los Angeles, United States. In Plos One, 2010
results identify a function for the FIIND and show that CARD8 and NLRP1 are ZU5-UPA domain-containing autoproteolytic proteins, thus suggesting a novel mechanism for regulating innate immune responses
Marfan's syndrome.
Dietz et al., Baltimore, United States. In Lancet, 2006
Marfan's syndrome is a systemic disorder of connective tissue caused by mutations in the extracellular matrix protein fibrillin 1. Cardinal manifestations include proximal aortic aneurysm, dislocation of the ocular lens, and long-bone overgrowth.
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
Tschopp et al., Lausanne, Switzerland. In Immunity, 2004
Here, we report that NALP2 and NALP3 associate with ASC, the CARD-containing protein Cardinal, and caspase-1 (but not caspase-5), thereby forming an inflammasome with high proIL-1beta-processing activity.
Slower heterosexual spread of HIV-2 than HIV-1.
Sankalé et al., Boston, United States. In Lancet, 1994
Between February 1985 and February 1993 in Dakar, Senegal, the Social Hygiene Clinic screened 1452 registered female prostitutes (5608 samples) for sexually transmitted diseases, including HIV-1 and HIV-2.
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